- Article
A Single Nucleotide Polymorphism Translates into a Radical Amino Acid Substitution at the Ligand-Binding Site in Fasciola hepatica Carboxylesterase B
- Estefan Miranda-Miranda,
- Silvana Scarcella,
- Enrique Reynaud,
- Verónica Narváez-Padilla,
- Gisela Neira,
- Roberto Mera-y-Sierra,
- Hugo Aguilar-Díaz and
- Raquel Cossio-Bayugar
Fasciola hepatica anthelmintic resistance may be associated with the catalytic activity of xenobiotic metabolizing enzymes. The gene expression of one of these enzymes, identified as carboxylesterase B (CestB), was previously described as inducible i...

