Sleep Polygenic Risk Score Is Associated with Cognitive Changes over Time
Abstract
:1. Introduction
2. Methods
3. Statistical Analysis
4. Results
5. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Characteristics | |
---|---|
Age, years Mean (SD) | 73.1 (5) |
Sex, women N (%) | 1184 (60.5) |
Education, years Mean (SD) | 8.4 (4.9) |
Cognitive domains | |
Memory, Mean (SD) | −0.1342 (0.94031) |
Executive, Mean (SD) | −0.1400 (0.78494) |
Visuo-spatial, Mean (SD) | −0.1963 (0.92621) |
Language, Mean (SD) | −0.0976 (0.90150) |
Attention/Speed, Mean (SD) | −0.1840 (1.14814) |
Duration of follow-up, years Mean (SD) | 3.1 (0.9) |
Total | 1376 |
Cognitive Ability | Β * | p |
---|---|---|
Memory | −551.69 | 0.173 |
−759.8 | 0.083 | |
Executive | −269.87 | 0.417 |
−161.71 | 0.655 | |
Visuo-spatial | −1305.22 | 0.018 |
−1273.59 | 0.031 | |
Language | 30.947 | 0.936 |
68.92 | 0.868 | |
Attention/Speed | 1253.22 | 0.058 |
1184.24 | 0.086 |
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Tsapanou, A.; Mourtzi, N.; Charisis, S.; Hatzimanolis, A.; Ntanasi, E.; Kosmidis, M.H.; Yannakoulia, M.; Hadjigeorgiou, G.; Dardiotis, E.; Sakka, P.; et al. Sleep Polygenic Risk Score Is Associated with Cognitive Changes over Time. Genes 2022, 13, 63. https://doi.org/10.3390/genes13010063
Tsapanou A, Mourtzi N, Charisis S, Hatzimanolis A, Ntanasi E, Kosmidis MH, Yannakoulia M, Hadjigeorgiou G, Dardiotis E, Sakka P, et al. Sleep Polygenic Risk Score Is Associated with Cognitive Changes over Time. Genes. 2022; 13(1):63. https://doi.org/10.3390/genes13010063
Chicago/Turabian StyleTsapanou, Angeliki, Niki Mourtzi, Sokratis Charisis, Alex Hatzimanolis, Eva Ntanasi, Mary H. Kosmidis, Mary Yannakoulia, Georgios Hadjigeorgiou, Efthimios Dardiotis, Paraskevi Sakka, and et al. 2022. "Sleep Polygenic Risk Score Is Associated with Cognitive Changes over Time" Genes 13, no. 1: 63. https://doi.org/10.3390/genes13010063
APA StyleTsapanou, A., Mourtzi, N., Charisis, S., Hatzimanolis, A., Ntanasi, E., Kosmidis, M. H., Yannakoulia, M., Hadjigeorgiou, G., Dardiotis, E., Sakka, P., Stern, Y., & Scarmeas, N. (2022). Sleep Polygenic Risk Score Is Associated with Cognitive Changes over Time. Genes, 13(1), 63. https://doi.org/10.3390/genes13010063