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Cells, Volume 7, Issue 1

2018 January - 8 articles

Cover Story: Bioassays of various types require that multiple cell types and reagents are pitapatted, often in complex patterns. As the cells and reagents are suspended/dissolved in cell culture media of one color, one has no visual feedback while pipetting, and there are no audit trails left to verify the accuracy and precision of the assay’s implementation. Here, using biologically neutral colored media, we introduce a reagent tracking platform that fills this gap. View this paper
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Articles (8)

  • Feature Paper
  • Article
  • Open Access
19 Citations
6,223 Views
17 Pages

Fine Regulation of Neutrophil Oxidative Status and Apoptosis by Ceruloplasmin and Its Derivatives

  • Ekaterina A. Golenkina,
  • Galina M. Viryasova,
  • Svetlana I. Galkina,
  • Tatjana V. Gaponova,
  • Galina F. Sud’ina and
  • Alexey V. Sokolov

12 January 2018

Timely neutrophil apoptosis is an essential part of the resolution phase of acute inflammation. Ceruloplasmin, an acute-phase protein, which is the predominant copper-carrying protein in the blood, has been suggested to have a marked effect on neutro...

  • Article
  • Open Access
17 Citations
6,403 Views
13 Pages

Effect of shRNA Mediated Silencing of YB-1 Protein on the Expression of Matrix Collagenases in Malignant Melanoma Cell In Vitro

  • Wisam Nabeel Ibrahim,
  • Abd Almonem Doolaanea and
  • Mohammad Syaiful Bahari Bin Abdull Rasad

10 January 2018

Background and Objective: YB-1 is a transcription and oncogenic factor capable of binding to DNA and RNA performing versatile functions within normal and cancer cells. Some studies reported the binding of YB-1 with a collagenases gene promoter and in...

  • Feature Paper
  • Review
  • Open Access
16 Citations
9,034 Views
17 Pages

Multiscale and Multimodal Approaches to Study Autophagy in Model Plants

  • Jessica Marion,
  • Romain Le Bars,
  • Laetitia Besse,
  • Henri Batoko and
  • Béatrice Satiat-Jeunemaitre

9 January 2018

Autophagy is a catabolic process used by eukaryotic cells to maintain or restore cellular and organismal homeostasis. A better understanding of autophagy in plant biology could lead to an improvement of the recycling processes of plant cells and thus...

  • Review
  • Open Access
34 Citations
10,703 Views
9 Pages

Targeting FLT3 Mutations in Acute Myeloid Leukemia

  • Riad El Fakih,
  • Walid Rasheed,
  • Yousef Hawsawi,
  • Maamoun Alsermani and
  • Mona Hassanein

8 January 2018

The FMS-like tyrosine kinase 3 (FLT3) pathway has an important role in cellular proliferation, survival, and differentiation. Acute myeloid leukemia (AML) patients with mutated FLT3 have a large disease burden at presentation and a dismal prognosis....

  • Article
  • Open Access
6 Citations
6,836 Views
10 Pages

Reagent Tracker Dyes Permit Quality Control for Verifying Plating Accuracy in ELISPOT Tests

  • Alexander Lehmann,
  • Zoltan Megyesi,
  • Anna Przybyla and
  • Paul V. Lehmann

3 January 2018

ELISPOT assays enable the detection of the frequency of antigen-specific T cells in the blood by measuring the secretion of cytokines, or combinations of cytokines, in response to antigenic challenges of a defined population of PBMC. As such, these a...

  • Feature Paper
  • Review
  • Open Access
25 Citations
8,284 Views
10 Pages

27 December 2017

Red blood cells and platelets are anucleate blood components indispensable for oxygen delivery and hemostasis, respectively. Derivation of these blood elements from induced pluripotent stem (iPS) cells has the potential to develop blood donor-indepen...

  • Review
  • Open Access
75 Citations
12,906 Views
11 Pages

26 December 2017

Mitochondria function to generate ATP and also play important roles in cellular homeostasis, signaling, apoptosis, autophagy, and metabolism. The loss of mitochondrial function results in cell death and various types of diseases. Therefore, quality c...

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Cells - ISSN 2073-4409