Next Article in Journal
Micrandilactone C, a Nortriterpenoid Isolated from Roots of Schisandra chinensis, Ameliorates Huntington’s Disease by Inhibiting Microglial STAT3 Pathways
Next Article in Special Issue
Transcriptome-Powered Pluripotent Stem Cell Differentiation for Regenerative Medicine
Previous Article in Journal
Context-Dependent Role of Glucocorticoid Receptor Alpha and Beta in Breast Cancer Cell Behaviour
Previous Article in Special Issue
Olfactory Regeneration with Nasally Administered Murine Adipose-Derived Stem Cells in Olfactory Epithelium Damaged Mice
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Cells
Volume 12
Issue 5
10.3390/cells12050785
cells-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Various AAV Serotypes and Their Applications in Gene Therapy: An Overview

by
Shaza S. Issa
1,
Alisa A. Shaimardanova
2,
Valeriya V. Solovyeva
2 and
Albert A. Rizvanov
2,*
1
Department of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia
2
Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia
*
Author to whom correspondence should be addressed.
Cells 2023, 12(5), 785; https://doi.org/10.3390/cells12050785
Submission received: 29 December 2022 / Revised: 22 February 2023 / Accepted: 26 February 2023 / Published: 1 March 2023
(This article belongs to the Special Issue Gene and Cell Therapy in Regenerative Medicine)
Browse Figure
Review Reports Versions Notes

Abstract

Despite scientific discoveries in the field of gene and cell therapy, some diseases still have no effective treatment. Advances in genetic engineering methods have enabled the development of effective gene therapy methods for various diseases based on adeno-associated viruses (AAVs). Today, many AAV-based gene therapy medications are being investigated in preclinical and clinical trials, and new ones are appearing on the market. In this article, we present a review of AAV discovery, properties, different serotypes, and tropism, and a following detailed explanation of their uses in gene therapy for disease of different organs and systems.
Keywords: AAV; gene therapy approach; serotype; tropism; gene therapy medication AAV; gene therapy approach; serotype; tropism; gene therapy medication

Share and Cite

MDPI and ACS Style

Issa, S.S.; Shaimardanova, A.A.; Solovyeva, V.V.; Rizvanov, A.A. Various AAV Serotypes and Their Applications in Gene Therapy: An Overview. Cells 2023, 12, 785. https://doi.org/10.3390/cells12050785

AMA Style

Issa SS, Shaimardanova AA, Solovyeva VV, Rizvanov AA. Various AAV Serotypes and Their Applications in Gene Therapy: An Overview. Cells. 2023; 12(5):785. https://doi.org/10.3390/cells12050785

Chicago/Turabian Style

Issa, Shaza S., Alisa A. Shaimardanova, Valeriya V. Solovyeva, and Albert A. Rizvanov. 2023. "Various AAV Serotypes and Their Applications in Gene Therapy: An Overview" Cells 12, no. 5: 785. https://doi.org/10.3390/cells12050785

APA Style

Issa, S. S., Shaimardanova, A. A., Solovyeva, V. V., & Rizvanov, A. A. (2023). Various AAV Serotypes and Their Applications in Gene Therapy: An Overview. Cells, 12(5), 785. https://doi.org/10.3390/cells12050785

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop