- Article
Monapinone Coupling Enzyme Produces Non-Natural Heterodimers
- Satoshi Ohte,
- Masayuki Toyoda,
- Keisuke Kobayashi,
- Isao Fujii,
- Taichi Ohshiro and
- Hiroshi Tomoda
The monapinone coupling enzyme (MCE), a fungal multicopper oxidase, catalyzes the regioselective C–C coupling between tricyclic monapinone A (the primary substrate) and other monapinones (secondary substrates) to produce atropisomeric biaryl homo- or...

