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Micromachines 2019, 10(1), 31; https://doi.org/10.3390/mi10010031

Wireless Electrochemical Detection on a Microfluidic Compact Disc (CD) and Evaluation of Redox-Amplification during Flow

1
Department of Mechanical and Aerospace Engineering, University of California Irvine, Irvine, CA 92697, USA
2
Department of Biomedical Engineering, University of California Irvine, Irvine, CA 92697, USA
3
School of Engineering and Sciences, Tecnologico de Monterrey, Monterrey 64849, NL, Mexico
*
Author to whom correspondence should be addressed.
Received: 9 November 2018 / Revised: 2 January 2019 / Accepted: 3 January 2019 / Published: 7 January 2019
(This article belongs to the Special Issue Electrochemical (Bio)sensors for Biomarkers Analysis)
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Abstract

Novel biomarkers and lower limits of detection enable improved diagnostics. In this paper we analyze the influence of flow on the lower limit of electrochemical detection on a microfluidic Compact Disc (CD). Implementing wireless transfer of data reduces noise during measurements and allows for real time sensing, demonstrated with the ferri-ferroyanide redox-couple in single and dual mode cyclic voltammetry. The impact of flow on redox-amplification and electrode integration for the lowest limit of detection are discussed. View Full-Text
Keywords: redox-amplification; CD microfluidics; wireless sensing; bioassay platform; collection efficiency; limit of detection; noise mitigation redox-amplification; CD microfluidics; wireless sensing; bioassay platform; collection efficiency; limit of detection; noise mitigation
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Bauer, M.; Bartoli, J.; Martinez-Chapa, S.O.; Madou, M. Wireless Electrochemical Detection on a Microfluidic Compact Disc (CD) and Evaluation of Redox-Amplification during Flow. Micromachines 2019, 10, 31.

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