Relationship between Inflammatory Food Consumption and Age-Related Hearing Loss in a Prospective Observational Cohort: Results from the Salus in Apulia Study
by
Rodolfo Sardone 1,*,†
, Luisa Lampignano 1,*,†, Vito Guerra 2, Roberta Zupo 1, Rossella Donghia 2, Fabio Castellana 1, Petronilla Battista 3, Ilaria Bortone 1, Filippo Procino 1, Marco Castellana 1, Andrea Passantino 3, Roberta Rucco 1, Madia Lozupone 4, Davide Seripa 5, Francesco Panza 1, Giovanni De Pergola 6, Gianluigi Giannelli 1, Giancarlo Logroscino 4,7, Heiner Boeing 8 and Nicola Quaranta 9
Rodolfo Sardone 1,*,†, Luisa Lampignano 1,*,†, Vito Guerra 2, Roberta Zupo 1, Rossella Donghia 2, Fabio Castellana 1, Petronilla Battista 3, Ilaria Bortone 1, Filippo Procino 1, Marco Castellana 1, Andrea Passantino 3, Roberta Rucco 1, Madia Lozupone 4, Davide Seripa 5, Francesco Panza 1, Giovanni De Pergola 6, Gianluigi Giannelli 1, Giancarlo Logroscino 4,7, Heiner Boeing 8 and Nicola Quaranta 9
1
Frailty Phenotypes Research Unit, “Salus in Apulia Study”, National Institute of Gastroenterology “Saverio de Bellis”, Research Hospital, Castellana Grotte, 70013 Bari, Italy
2
Data Analysis Unit, National Institute of Gastroenterology “Saverio de Bellis”, Research Hospital, Castellana Grotte, 70013 Bari, Italy
3
Department of Cardiology and Cardiac Rehabilitation, Scientific Clinical Institutes Maugeri, IRCCS Institute of Bari, 70124 Bari, Italy
4
Center for Neurodegenerative Diseases and the Aging Brain, University of Bari Aldo Moro, 70100 Bari, Italy
5
Research Laboratory, Complex Structure of Geriatrics, Department of Medical Sciences, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy
6
Clinical Nutrition Unit, Medical Oncology, Department of Biomedical Science and Human Oncology, University of Bari Aldo Moro, School of Medicine, 70100 Bari, Italy
7
Department of Clinical Research in Neurology, “Pia Fondazione Cardinale G. Panico”, Tricase, 73039 Lecce, Italy
8
German Institute of Human Nutrition Potsdam-Rehbrücke, 14558 Nuthetal, Germany
9
Otolaryngology Unit, Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari Aldo Moro, 70100 Bari, Italy
*
Authors to whom correspondence should be addressed.
†
These authors have equal contribution.
Nutrients 2020, 12(2), 426; https://doi.org/10.3390/nu12020426
Received: 15 January 2020 / Revised: 3 February 2020 / Accepted: 5 February 2020 / Published: 7 February 2020
(This article belongs to the Section Nutritional Epidemiology)
Age related hearing loss (ARHL) affects about one third of the elderly population. It is suggested that the senescence of the hair cells could be modulated by inflammation. Thus, intake of anti- and pro-inflammatory foods is of high interest. Methods: From the MICOL study population, 734 participants were selected that participated in the 2013 to 2018 examination including hearing ability and from which past data collected in 2005/2008 was available. ARHL status was determined and compared cross-sectionally and retrospectively according to clinical and lifestyle data including food and micronutrient intake. Results: ARHL status was associated with higher age but not with education, smoking, relative weight (BMI), and clinical-chemical blood markers in the crossectional and retrospective analyses. Higher intake of fruit juices among ARHL-participants was seen cross-sectionally, and of sugary foods, high-caloric drinks, beer, and spirits retrospectively. No difference was found for the other 26 food groups and for dietary micronutrients with the exception of past vitamin A, which was higher among normal hearing subjects. Conclusions: Pro-inflammatory foods with a high-sugar content and also beer and spirits were found to be assocated with positive ARHL-status, but not anti-inflammatory foods. Diet could be a candidate for lifestyle advice for the prevention of ARHL.
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Keywords:
age-related hearing loss; presbycusis; population studies; diet; food; sugar; alcohol; inflammation
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MDPI and ACS Style
Sardone, R.; Lampignano, L.; Guerra, V.; Zupo, R.; Donghia, R.; Castellana, F.; Battista, P.; Bortone, I.; Procino, F.; Castellana, M.; Passantino, A.; Rucco, R.; Lozupone, M.; Seripa, D.; Panza, F.; De Pergola, G.; Giannelli, G.; Logroscino, G.; Boeing, H.; Quaranta, N. Relationship between Inflammatory Food Consumption and Age-Related Hearing Loss in a Prospective Observational Cohort: Results from the Salus in Apulia Study. Nutrients 2020, 12, 426.
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