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Open AccessCommunication

Dysbiosis and Prematurity: Is There a Role for Probiotics?

Neonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and Human Oncology, “Aldo Moro” University of Bari, P.zza Giulio Cesare 11, 70124 Bari, Italy
Authors to whom correspondence should be addressed.
Maria Elisabetta Baldassarre and Antonio Di Mauro equally contributed to this work.
Nutrients 2019, 11(6), 1273;
Received: 10 April 2019 / Revised: 7 May 2019 / Accepted: 20 May 2019 / Published: 5 June 2019
(This article belongs to the Special Issue New Insights in Preterm Nutrition)
Healthy microbiota is a critical mediator in maintaining health and it is supposed that dysbiosis could have a role in the pathogenesis of a number of diseases. Evidence supports the hypothesis that maternal dysbiosis could act as a trigger for preterm birth; aberrant colonization of preterm infant gut might have a role in feeding intolerance and pathogenesis of necrotizing enterocolitis. Despite several clinical trials and meta-analyses, it is still not clear if modulation of maternal and neonatal microbiota with probiotic supplementation decreases the risk of preterm birth and its complications. View Full-Text
Keywords: “Dysbiosis” [MeSH]; “Premature Birth” [MeSH]; “Infant; Premature” [MeSH]; “Probiotics” [MeSH] “Dysbiosis” [MeSH]; “Premature Birth” [MeSH]; “Infant; Premature” [MeSH]; “Probiotics” [MeSH]
MDPI and ACS Style

Baldassarre, M.E.; Di Mauro, A.; Capozza, M.; Rizzo, V.; Schettini, F.; Panza, R.; Laforgia, N. Dysbiosis and Prematurity: Is There a Role for Probiotics? Nutrients 2019, 11, 1273.

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