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Journal of Xenobiotics, Volume 12, Issue 2

June 2022 - 6 articles

Cover Story: Nanocellulose is an innovative nanomaterial with enormous potential for use in a wide array of industrial and biomedical applications, and with fast-growing economic value. However, its expanding production is raising concerns about the potential health effects of unintentional human exposure. This study assessed the potential cytotoxic and genotoxic effects of two fibrillar and one crystalline micro-/nanocellulose in two mammalian cell lines (MG-63 and V79 cells). Cytotoxicity was analyzed via MTT and clonogenic assays, and genotoxicity via micronucleus assay. All nanocelluloses revealed cytotoxicity and genotoxicity, although at different concentrations, which may be related to their physicochemical differences, to differences in their cellular uptake, and to the DNA damage response of cell models. View this paper
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Articles (6)

  • Article
  • Open Access
13 Citations
3,969 Views
14 Pages

10 June 2022

Δ9-tetrahydrocannabinol (THC) is one of the primary ingredients of cannabis plants and is responsible for the psychoactive properties of cannabis. While cannabidiol (CBD), the non-psychoactive compound from cannabis, has been shown to stimulate...

  • Article
  • Open Access
15 Citations
8,555 Views
9 Pages

Vitamin B12 Deficiency and Clinical Neuropathy with Metformin Use in Type 2 Diabetes

  • Malik Dilaver Farooq,
  • Farooq Ahmad Tak,
  • Fauzia Ara,
  • Samia Rashid and
  • Irfan Ahmad Mir

31 May 2022

Introduction: Type 2 diabetes (T2DM), which is more prevalent (more than 90% of all diabetes cases) and the main driver of the diabetes epidemic, now affects 5.9% of the world’s adult population, with almost 80% of the total in developing count...

  • Article
  • Open Access
14 Citations
4,847 Views
13 Pages

9 May 2022

Ecotoxicity investigations of plastic nanoparticles (NPs) should pay more attention to their ability to pass barriers, accumulate, and initiate toxicity in cells. The purpose of this study was to develop a simple size exclusion chromatography (SEC) m...

  • Article
  • Open Access
12 Citations
4,647 Views
18 Pages

Genotoxicity of Three Micro/Nanocelluloses with Different Physicochemical Characteristics in MG-63 and V79 Cells

  • Célia Ventura,
  • Catarina Marques,
  • João Cadete,
  • Madalena Vilar,
  • Jorge F. S. Pedrosa,
  • Fátima Pinto,
  • Susete Nogueira Fernandes,
  • Rafaela Raupp da Rosa,
  • Maria Helena Godinho and
  • Paulo J. T. Ferreira
  • + 2 authors

21 April 2022

(1) Background: Nanocellulose is an innovative engineered nanomaterial with an enormous potential for use in a wide array of industrial and biomedical applications and with fast growing economic value. The expanding production of nanocellulose is lea...

  • Article
  • Open Access
31 Citations
4,245 Views
17 Pages

Toxicity Assessment and Control of Early Blight and Stem Rot of Solanum tuberosum L. by Mancozeb-Loaded Chitosan–Gum Acacia Nanocomposites

  • Ravinder Kumar,
  • Joginder Singh Duhan,
  • Anju Manuja,
  • Pawan Kaur,
  • Balvinder Kumar and
  • Pardeep Kumar Sadh

14 April 2022

Biopolymers such as chitosan and gum acacia are used for nanotechnological applications due to their biosafety and ecofriendly nature. The commercial fungicide mancozeb (M) was loaded into chitosan–gum acacia (CSGA) polymers to form nanocomposi...

  • Review
  • Open Access
6 Citations
4,516 Views
10 Pages

25 March 2022

The endocrine disruptors are mostly small organic molecules developed for numerous and very diverse industrial applications. They essentially act through nuclear receptors with small and hydrophobic endogenous ligands. Nevertheless, potential adverse...

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J. Xenobiot. - ISSN 2039-4713