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Neurology International, Volume 17, Issue 2

February 2025 - 17 articles

Cover Story: Migraine with aura involves cortical spreading depression, a wave of neuronal depolarization triggered by ion channel dysfunction, calcium surges, and excess glutamate. Despite its prevalence, MwA’s pathophysiology is incompletely understood. fMRI reveals visual cortex hyperactivation during auras and hypoactivity interictally, suggesting chronic excitability shifts. Genetic variants implicate calcium signaling, while advanced neuroimaging shows persistent network dysfunction. Distinct visual cortex activation patterns differentiate MwA from other headaches, suggesting diagnostic biomarker potential. View this paper
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Articles (17)

  • Brief Report
  • Open Access
1,111 Views
9 Pages

Introduction: Serum metabolome changes after acute ischemic stroke (AIS), but the significance of this is poorly understood. We evaluated whether this change is associated with AIS outcomes in patients with large vessel occlusion (LVO). To improve va...

  • Article
  • Open Access
1 Citations
1,606 Views
10 Pages

Etiology and Mortality of Nonconvulsive Status Epilepticus

  • Firdevs Ezgi Uçan Tokuç,
  • Emine Görgülü,
  • Fatma Genç,
  • Meltem Korucuk,
  • Abidin Erdal and
  • Yasemin Biçer Gömceli

Objectives: Nonconvulsive status epilepticus (NCSE) is a disease with a high mortality rate and a very diverse etiology. The disease prognosis is related to the etiology. We aimed to investigate the etiology, mortality rates, and factors affecting mo...

  • Case Report
  • Open Access
1,092 Views
8 Pages

Background: Metachromatic leukodystrophy (MLD) is a rare autosomal recessive disorder that causes demyelination of both the central (CNS) and peripheral nervous systems (PNS). Objective: This study aims to report a unique MLD case presenting with cra...

  • Article
  • Open Access
2 Citations
1,727 Views
11 Pages

Background/Objectives: Intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) are severe forms of stroke with high morbidity and mortality rates. HMG-CoA reductase inhibitors, commonly referred to as statins, known for their lipid-lowering...

  • Review
  • Open Access
15 Citations
5,830 Views
33 Pages

Alzheimer’s and Parkinson’s are the most common neurodegenerative diseases (NDDs). The development of aberrant protein aggregates and the progressive and permanent loss of neurons are the major characteristic features of these disorders....

  • Article
  • Open Access
2,027 Views
12 Pages

Cardiac CT in Large Vessel Occlusion Stroke for the Evaluation of Non-Thrombotic and Non-Atrial-Fibrillation-Related Embolic Causes

  • Karim Mostafa,
  • Cosima Wünsche,
  • Sarah Krutmann,
  • Carmen Wolf,
  • Schekeb Aludin,
  • Naomi Larsen,
  • Alexander Seiler,
  • Domagoj Schunk,
  • Olav Jansen and
  • Hatim Seoudy
  • + 1 author

Background: The purpose of this study is the evaluation of imaging findings of acute-phase cardiac CT (cCT) in stroke patients with large vessel occlusion (LVO) to identify potential cardioembolic sources (CES) in patients without intracardiac thromb...

  • Case Report
  • Open Access
1,866 Views
7 Pages

A Rare Case of Bickerstaff Encephalitis in Childhood: A Case Report

  • Luca Gregorio Giaccari,
  • Donatella Mastria,
  • Rosella Barbieri,
  • Rossella De Maglio,
  • Francesca Madaro,
  • Gianfranco Paiano,
  • Luciana Mascia,
  • Maria Caterina Pace,
  • Giuseppe Pulito and
  • Pasquale Sansone

Background: Bickerstaff brainstem encephalitis (BBE) is a rare autoimmune disease and approximately 74 cases have been reported in the literature, mostly in childhood. Methods: We reported this case report according to the CARE guidelines. Results: A...

  • Review
  • Open Access
2 Citations
3,472 Views
21 Pages

The Potential Role of Adipose-Derived Stem Cells in Regeneration of Peripheral Nerves

  • Sunil P. Mohan,
  • Sivan P. Priya,
  • Nada Tawfig,
  • Vivek Padmanabhan,
  • Rasha Babiker,
  • Arunkumar Palaniappan,
  • Srinivasan Prabhu,
  • Nallan CSK Chaitanya,
  • Muhammed Mustahsen Rahman and
  • Md Sofiqul Islam

Peripheral nerve injuries are common complications in surgical and dental practices, often resulting in functional deficiencies and reduced quality of life. Current treatment choices, such as autografts, have limitations, including donor site morbidi...

  • Case Report
  • Open Access
1,459 Views
8 Pages

Severe Headache and Deterioration of Vision in Left Eye in a Chronic Hemodialysis Patient Revealing a Brown Tumor of Sphenoid Sinus

  • Hicham Esselmani,
  • Abdelmohcine Aimrane,
  • Hicham Chatoui,
  • Omar El Hiba,
  • Mustapha Najimi and
  • Mohamed Merzouki

Background/Objectives: Brown tumors are rare bone lesions associated with hyperparathyroidism, particularly secondary hyperparathyroidism (SHPT), in chronic renal failure. While brown tumors commonly affect bones rich in marrow, the involvement of th...

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Neurol. Int. - ISSN 2035-8377