Pharmaceutics, Volume 13, Issue 11 (November 2021) – 244 articles
Hyaluronan-cholesterol nanogels (NHs) have been revealed to be effective ocular permeation enhancers. Owing to their bioadhesive properties, NHs firmly interact with the superficial corneal epithelium, without penetrating the stroma, thus modifying the transcorneal penetration of loaded therapeutics, as well as hydrophilic and hydrophobic therapeutics.
Therefore, NHs formulations can improve the ocular bioavailability of the instilled drugs, thus driving the application of HA-based NHs in the treatment of eye diseases. View this paper
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