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Biomedical Applications of Hyaluronic Acid-Based Nanomaterials in Hyperthermic Cancer Therapy

1
Department of Biomedical Sciences, Biomolecular Theranostics (BiT) Lab, Chonnam National University Medical School, Hwasun 58128, Korea
2
Department of Radiology, Biomolecular Theranostics (BiT) Lab, Chonnam National University Medical School, Hwasun 58128, Korea
*
Author to whom correspondence should be addressed.
Pharmaceutics 2019, 11(7), 306; https://doi.org/10.3390/pharmaceutics11070306
Received: 8 May 2019 / Revised: 18 June 2019 / Accepted: 24 June 2019 / Published: 1 July 2019
(This article belongs to the Special Issue Hyaluronic Acid for Biomedical Applications)
Hyaluronic acid (HA) is a non-sulfated polysaccharide polymer with the properties of biodegradability, biocompatibility, and non-toxicity. Additionally, HA specifically binds to certain receptors that are over-expressed in cancer cells. To maximize the effect of drug delivery and cancer treatment, diverse types of nanomaterials have been developed. HA-based nanomaterials, including micelles, polymersomes, hydrogels, and nanoparticles, play a critical role in efficient drug delivery and cancer treatment. Hyperthermic cancer treatment using HA-based nanomaterials has attracted attention as an efficient cancer treatment approach. In this paper, the biomedical applications of HA-based nanomaterials in hyperthermic cancer treatment and combined therapies are summarized. HA-based nanomaterials may become a representative platform in hyperthermic cancer treatment. View Full-Text
Keywords: hyaluronic acid (HA); nanomaterials; cancer; hyperthermia; photothermal therapy (PTT); magnetic hyperthermia therapy (MHT); combined cancer treatment hyaluronic acid (HA); nanomaterials; cancer; hyperthermia; photothermal therapy (PTT); magnetic hyperthermia therapy (MHT); combined cancer treatment
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Kim, S.; Moon, M.; Poilil Surendran, S.; Jeong, Y.Y. Biomedical Applications of Hyaluronic Acid-Based Nanomaterials in Hyperthermic Cancer Therapy. Pharmaceutics 2019, 11, 306.

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