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Viruses, Volume 9, Issue 4

April 2017 - 31 articles

Cover Story: The Ty1 restriction factor p22 is encoded by internally initiated Ty1i RNA. It contains two functional initiation codons embedded within a distinct structural domain. Mutational analyses suggest that the p22 level decreases when this RNA domain is destabilized at the secondary or tertiary structural levels. Also, our data support the idea that Gag itself and possibly other cellular proteins interact with the AUG-containing structural motif of Ty1i RNA to modulate its stability and translation. View this paper
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Articles (31)

  • Article
  • Open Access
23 Citations
6,763 Views
17 Pages

Replication and Oncolytic Activity of an Avian Orthoreovirus in Human Hepatocellular Carcinoma Cells

  • Robert A. Kozak,
  • Larissa Hattin,
  • Mia J. Biondi,
  • Juan C. Corredor,
  • Scott Walsh,
  • Max Xue-Zhong,
  • Justin Manuel,
  • Ian D. McGilvray,
  • Jason Morgenstern and
  • Evan Lusty
  • + 6 authors

24 April 2017

Oncolytic viruses are cancer therapeutics with promising outcomes in pre-clinical and clinical settings. Animal viruses have the possibility to avoid pre-existing immunity in humans, while being safe and immunostimulatory. We isolated an avian orthor...

  • Article
  • Open Access
59 Citations
8,715 Views
19 Pages

Deep Sequencing Analysis of RNAs from Citrus Plants Grown in a Citrus Sudden Death-Affected Area Reveals Diverse Known and Putative Novel Viruses

  • Emilyn E. Matsumura,
  • Helvecio D. Coletta-Filho,
  • Shahideh Nouri,
  • Bryce W. Falk,
  • Luca Nerva,
  • Tiago S. Oliveira,
  • Silvia O. Dorta and
  • Marcos A. Machado

24 April 2017

Citrus sudden death (CSD) has caused the death of approximately four million orange trees in a very important citrus region in Brazil. Although its etiology is still not completely clear, symptoms and distribution of affected plants indicate a viral...

  • Feature Paper
  • Review
  • Open Access
37 Citations
8,239 Views
23 Pages

Chloroviruses Have a Sweet Tooth

  • James L. Van Etten,
  • Irina Agarkova,
  • David D. Dunigan,
  • Michela Tonetti,
  • Christina De Castro and
  • Garry A. Duncan

22 April 2017

Chloroviruses are large double-stranded DNA (dsDNA) viruses that infect certain isolates of chlorella-like green algae. They contain up to approximately 400 protein-encoding genes and 16 transfer RNA (tRNA) genes. This review summarizes the unexpecte...

  • Conference Report
  • Open Access
4 Citations
6,490 Views
10 Pages

“French Phage Network”—Second Meeting Report

  • Clara Torres-Barceló,
  • Oliver Kaltz,
  • Rémy Froissart,
  • Sylvain Gandon,
  • Nicolas Ginet and
  • Mireille Ansaldi

21 April 2017

The study of bacteriophages (viruses of bacteria) includes a variety of approaches, such as structural biology, genetics, ecology, and evolution, with increasingly important implications for therapeutic and industrial uses. Researchers working with p...

  • Review
  • Open Access
221 Citations
30,003 Views
25 Pages

Classical Swine Fever—An Updated Review

  • Sandra Blome,
  • Christoph Staubach,
  • Julia Henke,
  • Jolene Carlson and
  • Martin Beer

21 April 2017

Classical swine fever (CSF) remains one of the most important transboundary viral diseases of swine worldwide. The causative agent is CSF virus, a small, enveloped RNA virus of the genus Pestivirus. Based on partial sequences, three genotypes can be...

  • Review
  • Open Access
50 Citations
9,341 Views
13 Pages

Porcine Circoviruses and Xenotransplantation

  • Joachim Denner and
  • Annette Mankertz

20 April 2017

Allotransplantation and xenotransplantation may be associated with the transmission of pathogens from the donor to the recipient. Whereas in the case of allotransplantation the transmitted microorganisms and their pathogenic effect are well character...

  • Article
  • Open Access
28 Citations
7,398 Views
18 Pages

Seasonal Dynamics of Haptophytes and dsDNA Algal Viruses Suggest Complex Virus-Host Relationship

  • Torill Vik Johannessen,
  • Aud Larsen,
  • Gunnar Bratbak,
  • António Pagarete,
  • Bente Edvardsen,
  • Elianne D. Egge and
  • Ruth-Anne Sandaa

20 April 2017

Viruses influence the ecology and diversity of phytoplankton in the ocean. Most studies of phytoplankton host–virus interactions have focused on bloom-forming species like Emiliania huxleyi or Phaeocystis spp. The role of viruses infecting phytoplank...

  • Review
  • Open Access
34 Citations
9,179 Views
13 Pages

20 April 2017

Human papillomavirus (HPV)-induced neoplasms have long been considered to originate from viral infection of the basal cell layer of the squamous mucosa. However, this paradigm has been recently undermined by accumulating data supporting the critical...

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Viruses - ISSN 1999-4915