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Article

Gold—Polyoxoborates Nanocomposite Prohibits Adsorption of Bacteriophages on Inner Surfaces of Polypropylene Labware and Protects Samples from Bacterial and Yeast Infections

Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Dann Turner
Viruses 2021, 13(7), 1206; https://doi.org/10.3390/v13071206
Received: 31 May 2021 / Revised: 15 June 2021 / Accepted: 18 June 2021 / Published: 23 June 2021
(This article belongs to the Special Issue Advances in Bacteriophage Biology)
Bacteriophages (phages) are a specific type of viruses that infect bacteria. Because of growing antibiotic resistance among bacterial strains, phage-based therapies are becoming more and more attractive. The critical problem is the storage of bacteriophages. Recently, it was found that bacteriophages might adsorb on the surfaces of plastic containers, effectively decreasing the titer of phage suspensions. Here, we showed that a BOA nanocomposite (gold nanoparticles embedded in polyoxoborate matrix) deposited onto the inner walls of the containers stabilizes phage suspensions against uncontrolled adsorption and titer decrease. Additionally, BOA provides antibacterial and antifungal protection. The application of BOA assures safe and sterile means for the storage of bacteriophages. View Full-Text
Keywords: bacteriophages; nanocomposite; surface coatings; antibacterial; antifungal; nanoparticles bacteriophages; nanocomposite; surface coatings; antibacterial; antifungal; nanoparticles
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MDPI and ACS Style

Wdowiak, M.; Ochirbat, E.; Paczesny, J. Gold—Polyoxoborates Nanocomposite Prohibits Adsorption of Bacteriophages on Inner Surfaces of Polypropylene Labware and Protects Samples from Bacterial and Yeast Infections. Viruses 2021, 13, 1206. https://doi.org/10.3390/v13071206

AMA Style

Wdowiak M, Ochirbat E, Paczesny J. Gold—Polyoxoborates Nanocomposite Prohibits Adsorption of Bacteriophages on Inner Surfaces of Polypropylene Labware and Protects Samples from Bacterial and Yeast Infections. Viruses. 2021; 13(7):1206. https://doi.org/10.3390/v13071206

Chicago/Turabian Style

Wdowiak, Mateusz, Enkhlin Ochirbat, and Jan Paczesny. 2021. "Gold—Polyoxoborates Nanocomposite Prohibits Adsorption of Bacteriophages on Inner Surfaces of Polypropylene Labware and Protects Samples from Bacterial and Yeast Infections" Viruses 13, no. 7: 1206. https://doi.org/10.3390/v13071206

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