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Review

Insights into Nanomedicine for Head and Neck Cancer Diagnosis and Treatment

by 1,2,3, 4,5 and 1,2,6,7,*
1
Center for Marine Sciences (CCMar), Gambelas Campus, University of Algarve, 8005-139 Faro, Portugal
2
Faculty of Sciences and Technology (FCT), Gambelas Campus, University of Algarve, 8005-139 Faro, Portugal
3
Faculty of Medicine and Biomedical Sciences (FMCB), Gambelas Campus, University of Algarve, 8005-139 Faro, Portugal
4
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Largo do Paço, 4700-000 Braga, Portugal
5
ICVS/3B’s, PT Government Associate Laboratory, Largo do Paço, 4700-000 Braga, Portugal
6
IBB—Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Técnico, University of Lisbon, 1049-001 Lisboa, Portugal
7
Associate Laboratory i4HB—Institute for Health and Bioeconomy at Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal
*
Author to whom correspondence should be addressed.
Academic Editor: Yury A. Skorik
Materials 2022, 15(6), 2086; https://doi.org/10.3390/ma15062086
Received: 30 December 2021 / Revised: 21 January 2022 / Accepted: 1 March 2022 / Published: 11 March 2022
(This article belongs to the Special Issue Polymer-Based Nanoparticles for Drug Delivery Applications)
Head and neck cancers rank sixth among the most common cancers today, and the survival rate has remained virtually unchanged over the past 25 years, due to late diagnosis and ineffective treatments. They have two main risk factors, tobacco and alcohol, and human papillomavirus infection is a secondary risk factor. These cancers affect areas of the body that are fundamental for the five senses. Therefore, it is necessary to treat them effectively and non-invasively as early as possible, in order to do not compromise vital functions, which is not always possible with conventional treatments (chemotherapy or radiotherapy). In this sense, nanomedicine plays a key role in the treatment and diagnosis of head and neck cancers. Nanomedicine involves using nanocarriers to deliver drugs to sites of action and reducing the necessary doses and possible side effects. The main purpose of this review is to give an overview of the applications of nanocarrier systems to the diagnosis and treatment of head and neck cancer. Herein, several types of delivery strategies, radiation enhancement, inside-out hyperthermia, and theragnostic approaches are addressed. View Full-Text
Keywords: head and neck cancer; nanomedicine; drug delivery; nanocarrier; hyperthermia; target therapeutic; theragnostic head and neck cancer; nanomedicine; drug delivery; nanocarrier; hyperthermia; target therapeutic; theragnostic
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MDPI and ACS Style

Viegas, C.; Pereira, D.S.M.; Fonte, P. Insights into Nanomedicine for Head and Neck Cancer Diagnosis and Treatment. Materials 2022, 15, 2086. https://doi.org/10.3390/ma15062086

AMA Style

Viegas C, Pereira DSM, Fonte P. Insights into Nanomedicine for Head and Neck Cancer Diagnosis and Treatment. Materials. 2022; 15(6):2086. https://doi.org/10.3390/ma15062086

Chicago/Turabian Style

Viegas, Cláudia, Daniela S.M. Pereira, and Pedro Fonte. 2022. "Insights into Nanomedicine for Head and Neck Cancer Diagnosis and Treatment" Materials 15, no. 6: 2086. https://doi.org/10.3390/ma15062086

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