Current Oncology, Volume 17, Issue 2

Historically, first-line treatment of non-small-cell lung cancer (NSCLC) has been based on giving a limited number of cycles of chemotherapy to achieve tumour response or stable disease. Patients are then observed without active therapy until disease...

Adjuvant therapies, including chemotherapy [...]

Background: Based on the TAX 327 phase iii trial, docetaxel-based chemotherapy is the standard first-line treatment for hormone-resistant prostate cancer (HRPC); however, there is some heterogeneity in the use of this agent in routine clinical practi...

Background: Sunitinib is approved for treatment of advanced renal cell carcinoma (RCC). Based on a clinical observation that patients receiving sunitinib developed macrocytosis, we undertook a study to further define this observation. Methods: In a r...

Colorectal carcinoma is the second most common cause of death in Canada. Because there is a precursor lesion (that is, the polyp), screening is critically important to prevent the disease through polyp removal—and failing that, to detect colorectal c...

I read the article by Drs. Rene, Cury, [...]

Objectives: Using primary and secondary data sources, we set out to estimate the Canadian wage loss from cancer for patients, caregivers, and parents from a patient and a societal perspective. Methods: First, a multiple-database literature search was...

specimens might be helpful in current practice and can aid in decision-making [...]

During the first three quarters of the twentieth century, radical mastectomy was an accepted and common procedure in the management of patients with earlystage cancer of the breast. After a lifetime of thinking about and working with patients with ea...

Hematopoietic stem-cell transplantation [...]