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Review

Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review

1
Department of Pharmacognosy, Faculty of Pharmacy, University of Szeged, Eötvös u. 6, 6720 Szeged, Hungary
2
Department of Horticultural Science, Faculty of Agriculture, Shahid Chamran University of Ahvaz, Ahvaz 61357-43311, Iran
3
Interdisciplinary Centre for Natural Products, University of Szeged, Eötvös u. 6, 6720 Szeged, Hungary
*
Authors to whom correspondence should be addressed.
Pharmaceuticals 2020, 13(8), 175; https://doi.org/10.3390/ph13080175
Received: 30 June 2020 / Revised: 22 July 2020 / Accepted: 29 July 2020 / Published: 31 July 2020
(This article belongs to the Special Issue Medicinal Plants 2020)
The rare genus Ducrosia (Apiaceae family) consists of six species, which are mainly native to Asia, specifically to Iran and Iraq. The aerial parts of D. anethifolia, as the most common species, have been traditionally consumed to relieve headache, backache and colic pain, and have also been used as an anxiolytic, an antidepressant, and for treating insomnia. The antispasmodic and carminative effects of D. assadii, and the analgesic activity of D. flabellifolia, along with the insecticidal activities and use as a remedy of skin infections of D. ismaelis, have been previously documented. Among the 49 non-volatile secondary metabolites identified from D. anethifolia and D. ismaelis, 17 linear furanocoumarins and 8 flavonoids have been characterized. The essential oil compositions of four species, including D. anethifolia, D. assadii, D. flabellifolia and D. ismaelis, have been analyzed, whereby aldehyde hydrocarbons, including decanal (10.1–74.0%) and dodecanal (7.2–33.41%), and α-pinene (4.0–70.3%), were identified as the main aroma constituents. From the species of the genus, the bioactivities of D. anethifolia, as well as D. ismaelis, D. assadii and D. flabellifolia, have been previously investigated. Except one clinical trial, all the pharmacological data are derived from preclinical tests, predominantly focusing on antimicrobial, antioxidant, antiproliferative and cytotoxic activities in vitro, and neuroprotective, antidiabetic and analgesic effects in vivo. Considering the vast ethnobotanical uses of the plants in Iranian folk medicine, the phytochemical and pharmacological analysis of un-investigated species might be promising. Furthermore, due to extensive consumption of the Ducrosia genus, more scientific data are needed to support the safety and efficacy of these plants. View Full-Text
Keywords: Ducrosia genus; folk medicine; phytoconstituents; non-volatile compounds; VOC; bioactivity Ducrosia genus; folk medicine; phytoconstituents; non-volatile compounds; VOC; bioactivity
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MDPI and ACS Style

Mottaghipisheh, J.; Boveiri Dehsheikh, A.; Mahmoodi Sourestani, M.; Kiss, T.; Hohmann, J.; Csupor, D. Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review. Pharmaceuticals 2020, 13, 175. https://doi.org/10.3390/ph13080175

AMA Style

Mottaghipisheh J, Boveiri Dehsheikh A, Mahmoodi Sourestani M, Kiss T, Hohmann J, Csupor D. Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review. Pharmaceuticals. 2020; 13(8):175. https://doi.org/10.3390/ph13080175

Chicago/Turabian Style

Mottaghipisheh, Javad, Anahita Boveiri Dehsheikh, Mohammad Mahmoodi Sourestani, Tivadar Kiss, Judit Hohmann, and Dezső Csupor. 2020. "Ducrosia spp., Rare Plants with Promising Phytochemical and Pharmacological Characteristics: An Updated Review" Pharmaceuticals 13, no. 8: 175. https://doi.org/10.3390/ph13080175

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