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N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, Russia
Author to whom correspondence should be addressed.
Academic Editor: R. Alan Aitken
Molbank 2022, 2022(2), M1389;
Received: 2 June 2022 / Revised: 16 June 2022 / Accepted: 16 June 2022 / Published: 17 June 2022
(This article belongs to the Section Organic Synthesis)
Functionally substituted 1,2-benzisoxazoles are very important and promising heterocycles with various pharmacological activities. Benzoxazoles containing reactive 3-chloromethyl and 5-amino groups are practically unexplored derivatives in this series. In this communication, the simple method for the synthesis of N-[3-(chloromethyl)-1,2-benzisoxazol-5-yl]acetamide which is an interesting precursor for the preparation of a series of 3,5-disubstituted benzoxazoles was described. The structure of the synthesized compound was established by elemental analysis, high-resolution mass spectrometry, 1H, 13C NMR and IR spectroscopy, and mass spectrometry. View Full-Text
Keywords: 1,2-benzisoxazoles; synthesis; N-[3-(chloromethyl)-1,2-benzisoxazol-5-yl]acetamide; ring closure 1,2-benzisoxazoles; synthesis; N-[3-(chloromethyl)-1,2-benzisoxazol-5-yl]acetamide; ring closure
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MDPI and ACS Style

Khodot, E.N.; Rakitin, O.A. N-[3-(Chloromethyl)-1,2-benzisoxazol-5-yl]acetamide. Molbank 2022, 2022, M1389.

AMA Style

Khodot EN, Rakitin OA. N-[3-(Chloromethyl)-1,2-benzisoxazol-5-yl]acetamide. Molbank. 2022; 2022(2):M1389.

Chicago/Turabian Style

Khodot, Evgeniy N., and Oleg A. Rakitin. 2022. "N-[3-(Chloromethyl)-1,2-benzisoxazol-5-yl]acetamide" Molbank 2022, no. 2: M1389.

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