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2,2′-(1,4-Phenylene)bis(7-nitro-1H-benzimidazole 3-oxide)

Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, CT 06269-3060, USA
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Author to whom correspondence should be addressed.
Academic Editor: Luke R. Odell
Molbank 2021, 2021(4), M1297; https://doi.org/10.3390/M1297
Received: 9 November 2021 / Revised: 19 November 2021 / Accepted: 19 November 2021 / Published: 22 November 2021
(This article belongs to the Section Organic Synthesis)
Bis(benzimidazol-2-yl-3-oxide)benzene derivatives have potential applications as energetic or photoactive materials. By using a two-step one-pot approach employing microwave heating as a tool, 2,2′-(1,4-phenylene)bis(7-nitro-1H-benzimidazole 3-oxide) (1) has been prepared in 94% yield. In the first step an SNAr reaction is performed using p-xylylenediamine as the central building block. Without isolating the intermediate, a base-mediated cyclization reaction follows in the second step. The product was isolated in analytically pure form by means of a pH-controlled precipitation. View Full-Text
Keywords: benzimidazole; benzimidazole N-oxide; microwave heating; two-step one-pot; precipitation benzimidazole; benzimidazole N-oxide; microwave heating; two-step one-pot; precipitation
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MDPI and ACS Style

Politano, F.; Gran-Magano, A.K.; Leadbeater, N.E. 2,2′-(1,4-Phenylene)bis(7-nitro-1H-benzimidazole 3-oxide). Molbank 2021, 2021, M1297. https://doi.org/10.3390/M1297

AMA Style

Politano F, Gran-Magano AK, Leadbeater NE. 2,2′-(1,4-Phenylene)bis(7-nitro-1H-benzimidazole 3-oxide). Molbank. 2021; 2021(4):M1297. https://doi.org/10.3390/M1297

Chicago/Turabian Style

Politano, Fabrizio, Ana K. Gran-Magano, and Nicholas E. Leadbeater 2021. "2,2′-(1,4-Phenylene)bis(7-nitro-1H-benzimidazole 3-oxide)" Molbank 2021, no. 4: M1297. https://doi.org/10.3390/M1297

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