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International Journal of Molecular Sciences, Volume 9, Issue 5

May 2008 - 17 articles

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Articles (17)

  • Article
  • Open Access
16 Citations
11,475 Views
12 Pages

Concerted Solvent Processes for Common Sulfonyl Chloride Precursors used in the Synthesis of Sulfonamide-based Drugs

  • Malcolm J. D’Souza,
  • Lamia Yaakoubd,
  • Stacey L. Mlynarski and
  • Dennis N. Kevill

Specific rates of solvolysis in hydroxylic solvents available for the solvolysis of 2-thiophenesulfonyl chloride and phenylmethanesulfonyl chloride are supplemented by determining the values in fluoroalcohol-containing solvents. The data sets are the...

  • Article
  • Open Access
41 Citations
12,048 Views
8 Pages

For possible future use in Photodynamic Therapy (PDT) and/or Photothermal Therapy (PTT) of cancer and screening of cancer cells a new type of ionic liquid photosensitizer –Cholinium-Purpurin-18 (Chol-Pu-18) – was synthesized and small gold (Au) nanop...

  • Article
  • Open Access
6 Citations
10,031 Views
33 Pages

Remarks on Muscle Contraction Mechanism

  • Toshio Mitsui and
  • Hiroyuki Ohshima

Muscle contraction mechanism is discussed by reforming the model described in an article by Mitsui (Adv. Biophys. 1999, 36, 107-158). A simple thermodynamic relationship is presented, which indicates that there is an inconsistency in the power stroke...

  • Article
  • Open Access
12 Citations
9,820 Views
8 Pages

Headspace Solid Phase Micro Extraction Gas Chromatographic Determination of Fenthion in Human Serum

  • Konstantinos M. Kasiotis,
  • Helen Souki,
  • Angelos N. Tsakirakis,
  • Haris Carageorgiou,
  • Spiridon A. Theotokatos,
  • Serkos A. Haroutounian and
  • Kyriaki Machera

A simple and effective analytical procedure was developed for the determination of fenthion residues in human serum samples. The sample treatment was performed using the headspace solid-phase micro extraction with polyacrylate fiber, which has the ad...

  • Review
  • Open Access
216 Citations
18,254 Views
21 Pages

The lignocellulose in forage crops represents a second generation of biomass feedstock for conversion into energy-related end products. Some of the most extensively studied species for cellulosic feedstock production include forages such as switchgra...

  • Review
  • Open Access
39 Citations
15,015 Views
18 Pages

Sublethal RNA Oxidation as a Mechanism for Neurodegenerative Disease

  • Rudy J. Castellani,
  • Akihiko Nunomura,
  • Raj K. Rolston,
  • Paula I. Moreira,
  • Atsushi Takeda,
  • George Perry and
  • Mark A. Smith

Although cellular RNA is subjected to the same oxidative insults as DNA and other cellular macromolecules, oxidative damage to RNA has not been a major focus in investigations of the biological consequences of free radical damage. In fact, because it...

  • Article
  • Open Access
139 Citations
16,222 Views
13 Pages

We report a new one phase method for the synthesis of uniform monodisperse crystalline Ag nanoparticles in aqueous systems that has been developed by using newly synthesized mono and dihydroxylated ionic liquids and cationic surfactants based on 1,3-...

  • Review
  • Open Access
73 Citations
17,385 Views
12 Pages

Red Wine Polyphenols for Cancer Prevention

  • Shan He,
  • Cuirong Sun and
  • Yuanjiang Pan

Conventional cancer therapies, the second leading cause of death worldwide, result in serious side effects and, at best, merely extend the patient's lifespan by a few years. Searching for effective prevention is of high priority in both basic and cli...

  • Review
  • Open Access
205 Citations
26,565 Views
10 Pages

Probiotics are live bacteria that could exert health beneficial effects upon consumption. In additional to their conventional use as gut modulators, probiotics are investigated for their role to prevent cancer. In-vivo and molecular studies have demo...

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Int. J. Mol. Sci. - ISSN 1422-0067