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International Journal of Molecular Sciences, Volume 11, Issue 2

February 2010 - 24 articles

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Articles (24)

  • Communication
  • Open Access
11 Citations
14,305 Views
10 Pages

Mutagenicity of New Lead Compounds to Treat Sickle Cell Disease Symptoms in a Salmonella/Microsome Assay

  • Jean Leandro Dos Santos,
  • Eliana A. Varanda,
  • Lídia Moreira Lima and
  • Chung Man Chin

25 February 2010

A series of phthalimide derivatives planned as drugs candidates to treat the symptoms of sickle cell anemia were evaluated in a mutagenicity test using strains of Salmonella typhimurium TA100 and TA102, without and with addition of S9 mixture, with t...

  • Article
  • Open Access
50 Citations
23,501 Views
17 Pages

24 February 2010

Functionalization of porous solids plays an important role in many areas, including heterogeneous catalysis and enzyme immobilization. In this study, large-pore ordered mesoporous SBA-15 molecular sieves were synthesized with tetraethyl orthosilicate...

  • Article
  • Open Access
12 Citations
11,087 Views
8 Pages

Lipid Vesicle Aggregation Induced by Cooling

  • Frank B. Howard and
  • Ira W. Levin

21 February 2010

Lipid bilayer fusion is a complex process requiring several intermediate steps. Initially, the two bilayers are brought into close contact following removal of intervening water layers and overcoming electrostatic repulsions between opposing bilayer...

  • Article
  • Open Access
2 Citations
11,324 Views
9 Pages

Bacterial Expression of Mouse Argonaute 2 for Functional and Mutational Studies

  • Vincenzo Salvatore,
  • Nicoletta Potenza,
  • Umberto Papa,
  • Valentina Nobile and
  • Aniello Russo

12 February 2010

RNA interference (RNAi) is a post-transcriptional gene-silencing process that occurs in many eukaryotic organisms upon intracellular exposure to double-stranded RNA. Argonaute 2 (Ago2) protein is the catalytic engine of mammalian RNAi. It contains a...

  • Article
  • Open Access
51 Citations
12,786 Views
12 Pages

Temporal and Spatial Regulation of miR-320 in the Uterus during Embryo Implantation in the Rat

  • Hong-Fei Xia,
  • Xiao-Hua Jin,
  • Pei-Pei Song,
  • Yi Cui,
  • Chun-Mei Liu and
  • Xu Ma

11 February 2010

The implantation process is complex, requiring reciprocal interactions between implantation-competent blastocysts and the receptive uterus. There were reports to show that some microRNAs (miRNAs) may play a key role during embryo implantation in mous...

  • Article
  • Open Access
11 Citations
9,246 Views
14 Pages

11 February 2010

2-Bromopropane (2-BP), an alternative to ozone-depleting solvents, is used as a cleaning solvent. Here, we examined the cytotoxic effects of 2-bromopropane (2-BP) on mouse embryos at the blastocyst stage, subsequent embryonic attachment and outgrowth...

  • Review
  • Open Access
23 Citations
14,415 Views
15 Pages

Molecular Design and Functional Control of Novel Self-Oscillating Polymers

  • Yusuke Hara,
  • Shingo Maeda,
  • Shuji Hashimoto and
  • Ryo Yoshida

10 February 2010

If we could realize an autonomous polymer system driven under biological conditions by a tailor-made molecular design, human beings could create unprecedented biomimetic functions and materials such as heartbeats, autonomous peristaltic pumps, etc. I...

  • Review
  • Open Access
10 Citations
15,213 Views
16 Pages

9 February 2010

Functionalizing of single molecules on surfaces has manifested great potential for bottom-up construction of complex devices on a molecular scale. We discuss the growth mechanism for the initial layers of polycyclic aromatic hydrocarbons on metal sur...

  • Article
  • Open Access
11 Citations
16,602 Views
19 Pages

9 February 2010

Separation of polyphenolic phytochemical compounds from their mixtures with sugars is necessary to produce an added-value sugar-reduced extract with high biological activity from fruit juice processing industry waste streams. The separation character...

  • Review
  • Open Access
51 Citations
15,615 Views
13 Pages

9 February 2010

Phenolic esters have attracted considerable interest due to the potential they offer for peroxidase catalysed cross-linking of cell wall polysaccharides. Particularly, feruloyl residues undergo radical coupling reactions that result in cross-linking...

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Int. J. Mol. Sci. - ISSN 1422-0067