Next Article in Journal
New Molecular Insights into the Inhibition of Dipeptidyl Peptidase-4 by Natural Cyclic Peptide Oxytocin
Previous Article in Journal
Soft Microwave Pretreatment to Extract P-Hydroxycinnamic Acids from Grass Stalks
Open AccessReview

Recent Advances in the Discovery of Novel Antiprotozoal Agents

College of Pharmacy, Gachon University, 191 Hambakmoe-ro, Yeonsu-gu, Incheon 21936, Korea
*
Author to whom correspondence should be addressed.
Authors contributed equally to this work.
Molecules 2019, 24(21), 3886; https://doi.org/10.3390/molecules24213886
Received: 3 October 2019 / Revised: 15 October 2019 / Accepted: 23 October 2019 / Published: 28 October 2019
(This article belongs to the Section Medicinal Chemistry)
Parasitic diseases have serious health, social, and economic impacts, especially in the tropical regions of the world. Diseases caused by protozoan parasites are responsible for considerable mortality and morbidity, affecting more than 500 million people worldwide. Globally, the burden of protozoan diseases is increasing and is been exacerbated because of a lack of effective medication due to the drug resistance and toxicity of current antiprotozoal agents. These limitations have prompted many researchers to search for new drugs against protozoan parasites. In this review, we have compiled the latest information (2012–2017) on the structures and pharmacological activities of newly developed organic compounds against five major protozoan diseases, giardiasis, leishmaniasis, malaria, trichomoniasis, and trypanosomiasis, with the aim of showing recent advances in the discovery of new antiprotozoal drugs. View Full-Text
Keywords: protozoan diseases; parasitic; giardiasis; leishmaniasis; malaria; trichomoniasis; trypanosomiasis protozoan diseases; parasitic; giardiasis; leishmaniasis; malaria; trichomoniasis; trypanosomiasis
Show Figures

Graphical abstract

MDPI and ACS Style

Lee, S.-M.; Kim, M.-S.; Hayat, F.; Shin, D. Recent Advances in the Discovery of Novel Antiprotozoal Agents. Molecules 2019, 24, 3886. https://doi.org/10.3390/molecules24213886

AMA Style

Lee S-M, Kim M-S, Hayat F, Shin D. Recent Advances in the Discovery of Novel Antiprotozoal Agents. Molecules. 2019; 24(21):3886. https://doi.org/10.3390/molecules24213886

Chicago/Turabian Style

Lee, Seong-Min; Kim, Min-Sun; Hayat, Faisal; Shin, Dongyun. 2019. "Recent Advances in the Discovery of Novel Antiprotozoal Agents" Molecules 24, no. 21: 3886. https://doi.org/10.3390/molecules24213886

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop