Next Article in Journal
Stability of Principal Hydrolysable Tannins from Trapa taiwanensis Hulls
Next Article in Special Issue
Effect of Selected Stilbenoids on Human Fecal Microbiota
Previous Article in Journal
Highly Efficient Synthesis of Substituted 3,4-Dihydropyrimidin-2-(1H)-ones (DHPMs) Catalyzed by Hf(OTf)4: Mechanistic Insights into Reaction Pathways under Metal Lewis Acid Catalysis and Solvent-Free Conditions
Previous Article in Special Issue
New Frontiers on the Metabolism, Bioavailability and Health Effects of Phenolic Compounds
Open AccessReview

Roles of Phenolic Compounds in the Reduction of Risk Factors of Cardiovascular Diseases

1
Thematic Task Force on Healthy Aging, CUECH Research Network, Universidad de Valparaíso, Angamos 655, Reñaca, Viña del Mar 2520000, Chile
2
Interdisciplinary Center for Health Studies, CIESAL, Faculty of Medicine, Universidad de Valparaíso, Angamos 655, Reñaca, Viña del Mar 2520000, Chile
3
Thrombosis Research Center, Department of Clinical Biochemistry and Immunohematology, Faculty of Health Sciences, Research Center for Aging, Universidad de Talca, 2 Norte 685, Talca 3460000, Chile
4
Escuela de Nutrición y Dietética, Facultad de Ciencias de la Salud, Universidad de Talca, Talca 3460000, Chile
*
Author to whom correspondence should be addressed.
Academic Editors: Pedro Mena and Rafael Llorach Asunción
Molecules 2019, 24(2), 366; https://doi.org/10.3390/molecules24020366
Received: 13 December 2018 / Revised: 9 January 2019 / Accepted: 12 January 2019 / Published: 21 January 2019
The population is now living longer during the period classified as “elderly” (60 years and older), exhibiting multimorbidity associated to the lengthening of the average life span. The dietary intake of phenolic compounds (PC) may affect the physiology, disease development and progression during the aging process, reducing risk factors of age related diseases. The aim of this review is to briefly describe some of the possible effects of a series of PC on the reduction of risk factors of the onset of cardiovascular diseases, considering their potential mechanisms of action. The main actions described for PC are associated with reduced platelet activity, anti-inflammatory effects, and the protection from oxidation to reduce LDL and the generation of advanced glycation end products. Preclinical and clinical evidence of the physiological effects of various PC is presented, as well as the health claims approved by regulatory agencies. View Full-Text
Keywords: phenolic compounds; aging; cardiovascular disease; platelets; oxidative stress; atherothrombosis; age related diseases; health claims phenolic compounds; aging; cardiovascular disease; platelets; oxidative stress; atherothrombosis; age related diseases; health claims
MDPI and ACS Style

Lutz, M.; Fuentes, E.; Ávila, F.; Alarcón, M.; Palomo, I. Roles of Phenolic Compounds in the Reduction of Risk Factors of Cardiovascular Diseases. Molecules 2019, 24, 366.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop