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Molecules 2018, 23(9), 2169; https://doi.org/10.3390/molecules23092169

Inclusion of Fructooligosaccharide and Resistant Maltodextrin in High Fat Diets Promotes Simultaneous Improvements on Body Fat Reduction and Fecal Parameters

1
Department of Food Science and Biotechnology, National Chung Hsing University, 145 Xingda Road, Taichung 40227, Taiwan
2
Syngen Biotech Co., Ltd., Building A, No. 154, Kaiyuan Rd., Sinying, Tainan 73055, Taiwan
*
Author to whom correspondence should be addressed.
Academic Editors: Min-Hsiung Pan and Filomena Conforti
Received: 6 August 2018 / Revised: 23 August 2018 / Accepted: 27 August 2018 / Published: 28 August 2018
(This article belongs to the Special Issue Natural Bioactives in Anti-Obesity Therapy)
Full-Text   |   PDF [209 KB, uploaded 28 August 2018]

Abstract

This study investigated the effects of incorporating a mixture of fructooligosaccharide (FOS) and resistant maltodextrin (RMD) at a ratio of 1:2 on body fat accumulation and fecal bacterial parameters in rats. Our results indicated that high dietary fat consumption might effectively (p < 0.05) increase body fat, but consequently inducing a significantly (p < 0.05) higher growth of C. perfringens and retarded growth (p < 0.05) of the Bifidobacterium spp. in the large intestine. As compared with the high fat control, an incorporation of the FOS and RMD mixture at a high dose (0.97 and 1.94 g/kg body weight, respectively) could result in a significant (p < 0.05) reduction in feed efficiency (−16%), total visceral fat (−17.4%), non-visceral fat levels (−20.3%), and total body fat (−19.2%). Furthermore, feeding the FOS and RMD mixture at a high dose was capable to counter the above undesirable impacts by reducing the C. perfringens count (−14.8%) and increasing the total Bifidobacterium count (134.4%) and total fecal short chain fatty acids (195.4%). A supplementation of adequate amount of FOS and RMD might confer a concreted solution to the obesity and deteriorated fecal bacteria profiles due to high fat consumption. View Full-Text
Keywords: body fat; fecal bacteria; fecal parameters; fructooligosaccharide; resistant maltodextrin body fat; fecal bacteria; fecal parameters; fructooligosaccharide; resistant maltodextrin
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Kao, W.-M.; Chang, C.-R.; Chang, T.-J.; Li, S.-Y.; Chen, W.-J.; Chau, C.-F. Inclusion of Fructooligosaccharide and Resistant Maltodextrin in High Fat Diets Promotes Simultaneous Improvements on Body Fat Reduction and Fecal Parameters. Molecules 2018, 23, 2169.

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