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Molecules 2018, 23(8), 1954; https://doi.org/10.3390/molecules23081954

Synthesis of Novel 1,4-Naphthoquinones Possessing Indole Scaffolds Using In(OTf)3 in Solvent-Free Conditions

1
College of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang 453003, Henan, China
2
School of Pharmacy, Xinxiang Medical University, Xinxiang 453003, Henan, China
*
Author to whom correspondence should be addressed.
Received: 11 July 2018 / Revised: 28 July 2018 / Accepted: 31 July 2018 / Published: 6 August 2018
(This article belongs to the Special Issue Multicomponent Reactions)
Full-Text   |   PDF [795 KB, uploaded 6 August 2018]   |  

Abstract

Novel 1,4-naphthoquinones possessing indole scaffolds were prepared by the reaction of 2-hydroxy-1,4-naphthoquinone-substituted salicylic aldehydes and indoles using In(OTf)3 as a catalyst. The method has the advantages of simple operation, mild reaction conditions, and friendly environment. View Full-Text
Keywords: 1,4-naphthoquinone; substituted salicylic aldehydes; indoles; solvent-free; green synthesis 1,4-naphthoquinone; substituted salicylic aldehydes; indoles; solvent-free; green synthesis
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Yang, X.; Wu, L. Synthesis of Novel 1,4-Naphthoquinones Possessing Indole Scaffolds Using In(OTf)3 in Solvent-Free Conditions. Molecules 2018, 23, 1954.

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