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Molecules 2017, 22(5), 828;

New Glycosides from the Fruits of Nicandra physaloides

Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, China
Authors to whom correspondence should be addressed.
Academic Editor: Isabel C. F. R. Ferreira
Received: 9 April 2017 / Revised: 16 May 2017 / Accepted: 16 May 2017 / Published: 17 May 2017
(This article belongs to the Collection Bioactive Compounds)
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Three new glycosides (13) and 15 known ones (418) were isolated and identified from the fruits of Nicandra physaloides. The structures of these compounds were established by 1D and 2D NMR spectra and HR-ESI-MS. The compounds (418) were the first time isolated from the Nicandra genus and they (except 8, 10, 14) exhibited inhibitions on the NO release of LPS-induced RAW 264.7 cells with IC50 values from 26.9 to 47.5 μM. View Full-Text
Keywords: Nicandra physaloides; phenyl-glycosides; fat glycosides; RAW 264.7; inflammation Nicandra physaloides; phenyl-glycosides; fat glycosides; RAW 264.7; inflammation

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Liu, Y.; Jiang, H.-B.; Xu, Z.-P.; Cheng, Y.-G.; Lv, S.-W.; Yang, B.-Y.; Guo, H.-W.; Kuang, H.-X. New Glycosides from the Fruits of Nicandra physaloides. Molecules 2017, 22, 828.

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