Phenolic Compounds from the Rhizomes of Smilax china L. and Their Anti-Inflammatory Activity
AbstractA new triflavanoid, kandelin B-5 (1), was isolated from the rhizomes of Smilax china L., together with six known phenylpropanoid substituted flavan-3-ols (2–7), nine flavonoids (8–16), two stilbenoids (17, 18), and two other compounds (19, 20). The structure of compound 1 was determined on the basis of 1D, 2D NMR and HR-ESI-MS data, as well as chemical method. Compounds 2–5, 8–12, 15, 17, and 19 were evaluated for anti-inflammatory activity. Only compounds 10, 15 and 17 showed slightly IL-1β expression inhibitory activities on LPS induced THP-1 cells, with inhibition rate of 15.8%, 37.3%, and 35.8%, respectively, at concentration of 50 μg/mL. View Full-Text
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Zhong, C.; Hu, D.; Hou, L.-B.; Song, L.-Y.; Zhang, Y.-J.; Xie, Y.; Tian, L.-W. Phenolic Compounds from the Rhizomes of Smilax china L. and Their Anti-Inflammatory Activity. Molecules 2017, 22, 515.
Zhong C, Hu D, Hou L-B, Song L-Y, Zhang Y-J, Xie Y, Tian L-W. Phenolic Compounds from the Rhizomes of Smilax china L. and Their Anti-Inflammatory Activity. Molecules. 2017; 22(4):515.Chicago/Turabian Style
Zhong, Cheng; Hu, Deng; Hou, Lian-Bing; Song, Lu-Yao; Zhang, Ying-Jun; Xie, Yang; Tian, Li-Wen. 2017. "Phenolic Compounds from the Rhizomes of Smilax china L. and Their Anti-Inflammatory Activity." Molecules 22, no. 4: 515.
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