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Molecules 2016, 21(8), 1075;

Steroidal Saponins from the Rhizomes of Anemarrhena asphodeloides

Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, China
Author to whom correspondence should be addressed.
Academic Editors: Nancy D. Turner and Isabel C. F. R. Ferreira
Received: 19 May 2016 / Revised: 28 July 2016 / Accepted: 1 August 2016 / Published: 17 August 2016
(This article belongs to the Collection Bioactive Compounds)
Full-Text   |   PDF [997 KB, uploaded 17 August 2016]   |  


Four new steroid saponins 14 were isolated from the rhizomes of Anemarrhena asphodeloides (Asparagaceae), as well as four known saponins: anemarsaponin B (5) timosaponin D (6), timosaponin E1 (7) anemarsaponin B II (8). Their structures were established through UV and NMR as well as MS data. All the compounds were evaluated for cytotoxicity against HepG2 and SGC7901 human cancer lines. Compounds 3 and 7 displayed medium antiproliferative activities on HepG2 and SGC7901 cells, with IC50 values of 43.90 and 57.90 μM, respectively. View Full-Text
Keywords: Asparagaceae; furostanol saponin; spirostanol saponin; MTT; cytotoxicity Asparagaceae; furostanol saponin; spirostanol saponin; MTT; cytotoxicity

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Yang, B.-Y.; Zhang, J.; Liu, Y.; Kuang, H.-X. Steroidal Saponins from the Rhizomes of Anemarrhena asphodeloides. Molecules 2016, 21, 1075.

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