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Entropy, Volume 19, Issue 3 (March 2017)
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Cover Story (view full-size image) Free energy transduction can be obtained when external oscillating fields couple to internal [...] Read more. Free energy transduction can be obtained when external oscillating fields couple to internal conformational fluctuations contributing to the maintenance of a non-equilibrium state. This would explain the high efficiencies observed in the mechanisms of electrochemical signaling in living cells. The use of structure-based theoretical approaches allows assessing how fluctuation-driven transport occurs in confined systems such as protein channels with unprecedented detail. View this paper