Topical Collection "Programmed Cell Death and Apoptosis"

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A topical collection in International Journal of Molecular Sciences (ISSN 1422-0067). This collection belongs to the section "Molecular Pathology".

Editor

Collection Editor
Prof. Dr. Anthony Lemarié
Research Team: Tumor radioresistance, from signalling pathways to therapy Department of Experimental Therapeutics Inserm U1037 Toulouse Cancer Research Center (CRCT) & IUCT 2 av. Hubert Curien, 31100 Toulouse, FRANCE
E-Mail: anthony.lemarie@inserm.fr
Interests: cell death; apoptosis; cellular differentiation; cellular and mitochondrial metabolism; cellular and mitochondrial homoeostasis; oxidative stress; cancer; cancer stem cells; glioma; radiotherapy & radioresistance

Topical Collection Information

Dear Colleagues,

Apoptosis is considered as an essential physiological process in eukaryotes for development, tissue homeostasis, wound healing or immune response. Moreover, apoptosis appears as a key player in physiopathological deregulations, since sustained apoptotic cell death characterizes ischemic and degenerative diseases as well as toxicological responses and since impaired cell death confers to cells and tissues a hyperproliferative phenotype as observed in cancer cells or autoimmune diseases. This collection is dedicated to bring to light some recent developments in the cell death area and to further present some comprehensive reviews on specific “hot” spots in the apoptotic field. In particular, it is of major interest to present the different types of programmed cell death, such as apoptosis, autophagic cell death, necroptosis and secondary necrosis, mitotic catastrophe or senescence and to depict their specific mechanisms and crossovers. The physiopathological context of each process is of particular importance. In addition, the different upstream early events leading to cell death signalling remain to be fully deciphered, notably the role of oxidative stress, ionic homeostasis, metabolic stress signals (e.g. hypoxia), DNA damages and microRNAs.
Concerning apoptosis, several aspects have to be addressed as the dependency on the caspase proteases, the involvement of extrinsic (death receptors) and intrinsic (mitochondrial) pathways and the role of the endoplasmic reticulum pathway. Finally, it would be of great interest to focus on the pro-survival vs pro-apoptotic regulation in tumour cells and during anticancer treatments (either chemo or radiotherapy), particularly towards several emerging targets such as cancer stem cells or circulating cancer cells.
Research articles, review articles as well as communications are invited.

Prof. Dr. Anthony Lemarié
Collection Editor

Manuscript Submission Information

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Keywords

  • cell death
  • apoptosis
  • cellular differentiation
  • cellular and mitochondrial metabolism
  • cellular and mitochondrial homoeostasis
  • oxidative stress
  • cancer
  • cancer stem cells
  • glioma
  • radiotherapy & radioresistance

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Published Papers (50 papers)

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2014  ( 28 papers )


2013  ( 8 papers )


2012  ( 14 papers )


2014
by , ,  and
Int. J. Mol. Sci. 2014, 15(10), 18762-18775; doi:10.3390/ijms151018762
Received: 3 June 2014; in revised form: 2 September 2014 / Accepted: 11 September 2014 / Published: 17 October 2014
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by ,  and
Int. J. Mol. Sci. 2014, 15(10), 18557-18573; doi:10.3390/ijms151018557
Received: 27 August 2014; in revised form: 30 September 2014 / Accepted: 2 October 2014 / Published: 14 October 2014
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Int. J. Mol. Sci. 2014, 15(10), 17974-17999; doi:10.3390/ijms151017974
Received: 11 June 2014; in revised form: 11 September 2014 / Accepted: 23 September 2014 / Published: 8 October 2014
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Int. J. Mol. Sci. 2014, 15(8), 14298-14312; doi:10.3390/ijms150814298
Received: 31 May 2014; in revised form: 14 July 2014 / Accepted: 23 July 2014 / Published: 15 August 2014
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by , , , , ,  and
Int. J. Mol. Sci. 2014, 15(8), 13833-13848; doi:10.3390/ijms150813833
Received: 12 May 2014; in revised form: 25 July 2014 / Accepted: 26 July 2014 / Published: 11 August 2014
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by , ,  and
Int. J. Mol. Sci. 2014, 15(6), 10034-10051; doi:10.3390/ijms150610034
Received: 3 April 2014; in revised form: 17 April 2014 / Accepted: 19 May 2014 / Published: 5 June 2014
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by , , ,  and
Int. J. Mol. Sci. 2014, 15(5), 8335-8351; doi:10.3390/ijms15058335
Received: 24 February 2014; in revised form: 18 April 2014 / Accepted: 18 April 2014 / Published: 12 May 2014
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by , , , , ,  and
Int. J. Mol. Sci. 2014, 15(4), 6625-6640; doi:10.3390/ijms15046625
Received: 29 January 2014; in revised form: 9 April 2014 / Accepted: 9 April 2014 / Published: 17 April 2014
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by , , ,  and
Int. J. Mol. Sci. 2014, 15(4), 6657-6673; doi:10.3390/ijms15046657
Received: 24 January 2014; in revised form: 4 April 2014 / Accepted: 8 April 2014 / Published: 17 April 2014
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by , , ,  and
Int. J. Mol. Sci. 2014, 15(4), 5988-6001; doi:10.3390/ijms15045988
Received: 12 November 2013; in revised form: 5 March 2014 / Accepted: 24 March 2014 / Published: 9 April 2014
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by , ,  and
Int. J. Mol. Sci. 2014, 15(4), 5596-5622; doi:10.3390/ijms15045596
Received: 27 January 2014; in revised form: 4 March 2014 / Accepted: 17 March 2014 / Published: 1 April 2014
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by , , , ,  and
Int. J. Mol. Sci. 2014, 15(4), 5388-5409; doi:10.3390/ijms15045388
Received: 7 February 2014; in revised form: 7 March 2014 / Accepted: 20 March 2014 / Published: 27 March 2014
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by , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(4), 5304-5322; doi:10.3390/ijms15045304
Received: 14 November 2013; in revised form: 7 February 2014 / Accepted: 14 March 2014 / Published: 26 March 2014
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by  and
Int. J. Mol. Sci. 2014, 15(3), 4977-4993; doi:10.3390/ijms15034977
Received: 3 February 2014; in revised form: 27 February 2014 / Accepted: 12 March 2014 / Published: 20 March 2014
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by , , ,  and
Int. J. Mol. Sci. 2014, 15(3), 4356-4392; doi:10.3390/ijms15034356
Received: 20 December 2013; in revised form: 7 February 2014 / Accepted: 21 February 2014 / Published: 12 March 2014
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by , , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(3), 4318-4332; doi:10.3390/ijms15034318
Received: 22 December 2013; in revised form: 10 February 2014 / Accepted: 26 February 2014 / Published: 11 March 2014
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by ,  and
Int. J. Mol. Sci. 2014, 15(3), 3952-3969; doi:10.3390/ijms15033952
Received: 17 January 2014; in revised form: 20 February 2014 / Accepted: 26 February 2014 / Published: 5 March 2014
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by , , ,  and
Int. J. Mol. Sci. 2014, 15(3), 3746-3767; doi:10.3390/ijms15033746
Received: 23 December 2013; in revised form: 10 February 2014 / Accepted: 19 February 2014 / Published: 3 March 2014
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by , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(3), 3816-3833; doi:10.3390/ijms15033816
Received: 12 December 2013; in revised form: 30 January 2014 / Accepted: 6 February 2014 / Published: 3 March 2014
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by  and
Int. J. Mol. Sci. 2014, 15(3), 3403-3431; doi:10.3390/ijms15033403
Received: 18 December 2013; in revised form: 22 January 2014 / Accepted: 14 February 2014 / Published: 25 February 2014
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by , ,  and
Int. J. Mol. Sci. 2014, 15(2), 3145-3153; doi:10.3390/ijms15023145
Received: 6 January 2014; in revised form: 10 February 2014 / Accepted: 13 February 2014 / Published: 21 February 2014
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by , , , ,  and
Int. J. Mol. Sci. 2014, 15(2), 2660-2671; doi:10.3390/ijms15022660
Received: 8 November 2013; in revised form: 3 January 2014 / Accepted: 13 February 2014 / Published: 17 February 2014
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by ,  and
Int. J. Mol. Sci. 2014, 15(2), 2672-2694; doi:10.3390/ijms15022672
Received: 25 December 2013; in revised form: 10 February 2014 / Accepted: 11 February 2014 / Published: 17 February 2014
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by ,  and
Int. J. Mol. Sci. 2014, 15(2), 2494-2516; doi:10.3390/ijms15022494
Received: 30 December 2013; in revised form: 31 January 2014 / Accepted: 7 February 2014 / Published: 13 February 2014
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by , , , , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(2), 2172-2190; doi:10.3390/ijms15022172
Received: 17 November 2013; in revised form: 25 December 2013 / Accepted: 23 January 2014 / Published: 29 January 2014
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by , , , , ,  and
Int. J. Mol. Sci. 2014, 15(2), 1983-2002; doi:10.3390/ijms15021983
Received: 23 October 2013; in revised form: 20 January 2014 / Accepted: 22 January 2014 / Published: 27 January 2014
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by , , , ,  and
Int. J. Mol. Sci. 2014, 15(1), 1538-1553; doi:10.3390/ijms15011538
Received: 9 December 2013; in revised form: 21 December 2013 / Accepted: 13 January 2014 / Published: 21 January 2014
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by , , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(1), 484-503; doi:10.3390/ijms15010484
Received: 10 October 2013; in revised form: 12 December 2013 / Accepted: 16 December 2013 / Published: 2 January 2014
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2013
by ,  and
Int. J. Mol. Sci. 2013, 14(12), 24656-24669; doi:10.3390/ijms141224656
Received: 1 September 2013; in revised form: 5 December 2013 / Accepted: 9 December 2013 / Published: 18 December 2013
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by , , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(12), 24742-24754; doi:10.3390/ijms141224742
Received: 24 September 2013; in revised form: 3 November 2013 / Accepted: 4 November 2013 / Published: 18 December 2013
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by , , , ,  and
Int. J. Mol. Sci. 2013, 14(12), 23441-23453; doi:10.3390/ijms141223441
Received: 21 September 2013; in revised form: 12 November 2013 / Accepted: 19 November 2013 / Published: 28 November 2013
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by , , , ,  and
Int. J. Mol. Sci. 2013, 14(12), 23274-23288; doi:10.3390/ijms141223274
Received: 22 September 2013; in revised form: 8 November 2013 / Accepted: 13 November 2013 / Published: 26 November 2013
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by , ,  and
Int. J. Mol. Sci. 2013, 14(11), 22782-22795; doi:10.3390/ijms141122782
Received: 24 September 2013; in revised form: 11 November 2013 / Accepted: 11 November 2013 / Published: 19 November 2013
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by , , ,  and
Int. J. Mol. Sci. 2013, 14(11), 22483-22498; doi:10.3390/ijms141122483
Received: 26 August 2013; in revised form: 18 October 2013 / Accepted: 1 November 2013 / Published: 14 November 2013
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by ,  and
Int. J. Mol. Sci. 2013, 14(10), 20139-20156; doi:10.3390/ijms141020139
Received: 1 July 2013; in revised form: 26 September 2013 / Accepted: 26 September 2013 / Published: 9 October 2013
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by , , , , ,  and
Int. J. Mol. Sci. 2013, 14(3), 6074-6089; doi:10.3390/ijms14036074
Received: 14 January 2013; in revised form: 3 February 2013 / Accepted: 28 February 2013 / Published: 15 March 2013
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2012
by , ,  and
Int. J. Mol. Sci. 2013, 14(1), 177-190; doi:10.3390/ijms14010177
Received: 30 July 2012; in revised form: 6 November 2012 / Accepted: 10 December 2012 / Published: 21 December 2012
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by , , ,  and
Int. J. Mol. Sci. 2012, 13(12), 16472-16488; doi:10.3390/ijms131216472
Received: 22 October 2012; in revised form: 23 November 2012 / Accepted: 27 November 2012 / Published: 4 December 2012
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by ,  and
Int. J. Mol. Sci. 2012, 13(11), 13911-13925; doi:10.3390/ijms131113911
Received: 24 September 2012; in revised form: 25 October 2012 / Accepted: 25 October 2012 / Published: 29 October 2012
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by , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(9), 11923-11940; doi:10.3390/ijms130911923
Received: 28 June 2012; in revised form: 5 September 2012 / Accepted: 11 September 2012 / Published: 20 September 2012
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by , , ,  and
Int. J. Mol. Sci. 2012, 13(8), 9877-9892; doi:10.3390/ijms13089877
Received: 1 June 2012; in revised form: 6 July 2012 / Accepted: 26 July 2012 / Published: 8 August 2012
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by , , , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(8), 9627-9641; doi:10.3390/ijms13089627
Received: 30 May 2012; in revised form: 15 July 2012 / Accepted: 25 July 2012 / Published: 2 August 2012
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by , ,  and
Int. J. Mol. Sci. 2012, 13(8), 9649-9672; doi:10.3390/ijms13089649
Received: 18 June 2012; in revised form: 23 July 2012 / Accepted: 24 July 2012 / Published: 2 August 2012
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by , ,  and
Int. J. Mol. Sci. 2012, 13(8), 9545-9571; doi:10.3390/ijms13089545
Received: 8 June 2012; in revised form: 13 July 2012 / Accepted: 17 July 2012 / Published: 30 July 2012
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by , ,  and
Int. J. Mol. Sci. 2012, 13(7), 9363-9379; doi:10.3390/ijms13079363
Received: 30 May 2012; in revised form: 18 July 2012 / Accepted: 19 July 2012 / Published: 24 July 2012
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by , , , , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(7), 9069-9080; doi:10.3390/ijms13079069
Received: 24 May 2012; in revised form: 3 July 2012 / Accepted: 4 July 2012 / Published: 20 July 2012
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by , , ,  and
Int. J. Mol. Sci. 2012, 13(7), 8834-8852; doi:10.3390/ijms13078834
Received: 1 June 2012; in revised form: 30 June 2012 / Accepted: 4 July 2012 / Published: 16 July 2012
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by ,  and
Int. J. Mol. Sci. 2012, 13(7), 7886-7901; doi:10.3390/ijms13077886
Received: 1 June 2012; in revised form: 18 June 2012 / Accepted: 20 June 2012 / Published: 25 June 2012
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by , , , , ,  and
Int. J. Mol. Sci. 2012, 13(6), 6548-6560; doi:10.3390/ijms13066548
Received: 17 April 2012; in revised form: 21 May 2012 / Accepted: 22 May 2012 / Published: 29 May 2012
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by , , , , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(5), 6246-6265; doi:10.3390/ijms13056246
Received: 13 March 2012; in revised form: 9 May 2012 / Accepted: 11 May 2012 / Published: 21 May 2012
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Last update: 7 August 2014

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert