1-Benzyl-2-Phenylbenzimidazole (BPB), a Benzimidazole Derivative, Induces Cell Apoptosis in Human Chondrosarcoma through Intrinsic and Extrinsic Pathways

¹ Central Laboratory, Shin Kong Wu Ho-Su Memorial Hospital, No.95, Wunchang Road, Shihlin District, Taipei City 111, Taiwan ² Graduate Institute of Pharmaceutical Chemistry, China Medical University, No.91 Hsueh-Shih Road, Taichung 40402, Taiwan ³ Department of Biotechnology, College of Health Science, Asia University, No.500, Lioufeng Road, Wufeng, Taichung 41354, Taiwan ⁴ Department of Orthopedic Surgery, Taichung Hospital, Department of Health, No.199, Sec. 1, San-Min Road, Taichung 402, Taiwan ⁵ Graduate Institute of Biotechnology, National Chung Hsing University, No.250 Kuo Kuang Road, Taichung 402, Taiwan ⁶ School of Chinese Medicine, China Medical University, No.91 Hsueh-Shih Road, Taichung 404, Taiwan ⁷ Department of Pharmacology, School of Medicine, China Medical University, No.91 Hsueh-Shih Road, Taichung 40402, Taiwan ⁸ Graduate Institute of Basic Medical Science, China Medical University, No.91 Hsueh-Shih Road, Taichung 404, Taiwan ^† These authors contributed equally to this work.