A Time to Kill: Targeting Apoptosis in Cancer
AbstractThe process of apoptosis is essential for maintaining the physiologic balance between cell death and cell growth. This complex process is executed by two major pathways that participate in activating an executioner mechanism leading to chromatin disintegration and nuclear fragmentation. Dysregulation of these pathways often contributes to cancer development and resistance to cancer therapy. Here, we review the most recent discoveries in apoptosis regulation and possible mechanisms for resensitizing tumor cells to therapy. View Full-Text
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Koff, J.L.; Ramachandiran, S.; Bernal-Mizrachi, L. A Time to Kill: Targeting Apoptosis in Cancer. Int. J. Mol. Sci. 2015, 16, 2942-2955.
Koff JL, Ramachandiran S, Bernal-Mizrachi L. A Time to Kill: Targeting Apoptosis in Cancer. International Journal of Molecular Sciences. 2015; 16(2):2942-2955.Chicago/Turabian Style
Koff, Jean L.; Ramachandiran, Sampath; Bernal-Mizrachi, Leon. 2015. "A Time to Kill: Targeting Apoptosis in Cancer." Int. J. Mol. Sci. 16, no. 2: 2942-2955.