Advances in Ovarian Cancer Research: From Biology to Therapeutics
Topic Information
Dear Colleagues,
Recently, substantial progress has been made in treating ovarian cancer, predominantly based on the identification of new molecular targets. For example, PARP inhibitors have been successful largely due to their efficacy in cancers that harbor BRCA mutations or evidence of deficiency in the homologous recombination DNA repair pathway. This collection of articles will address the biological discoveries leading to the next breakthroughs in ovarian cancer research and treatment. Authors are encouraged to submit research studies with translational potential, especially those that include novel biomarkers for treatment effects. This Topic thus provides a framework for integrating discoveries at the bench and the bedside.
Dr. Christina M. Annunziata
Prof. Dr. Adam R. Karpf
Topic Editors
Keywords
- ovarian cancer
- translational research
- biomarkers
- genetics
- epigenetics
- clinical trials
- tumor biology
- drug discovery
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