News and Updates on Probiotics

Topic Information

Dear Colleagues,

Probiotics are commonly recognized as functional microorganisms that are able to exert a positive effect on human health. Although both the mechanism of action and the effect of pathogens on human hosts have been extensively studied, the attention of the scientific community has only recently shifted towards the beneficial role played by microorganisms with probiotic features. Increasing evidence demonstrates that microorganisms with claimed probiotic properties could benefit human (in different age groups) and animal health by modulating the host’s metabolism, physiology, nutrition, and immune functions. In addition, based on the available literature, probiotics have emerged as agents that are able not only to maintain a healthy status but also to prevent and treat dysbiosis. The Topic “News and Updates of Probiotics" aims at increasing knowledge about probiotic functions; molecular mechanisms of the host-microbe interactions that enable beneficial outcomes; identification, characterization, and the mechanisms of action of bioactive molecules produced by probiotics; and the development of innovative strategies for the prevention and treatment of diseases and dysbiosis. This Topic plans to publish original basic research articles, clinical studies, reviews, and perspectives that contribute to understanding probiotics, their mechanisms of action, health benefits, and applications in various fields. Potential topics include (but are not limited to) the following:

• Isolation, identification, and characterization of new probiotic strains;
• Studying the mechanisms of action by which probiotics exert health-promoting effects on the host, including interactions with microbiota, modulation of the immune function, and production of bioactive compounds;
• Clinical trials and epidemiological studies investigating the health effects of probiotics in the prevention and treatment of various dysbiosis and pathologic conditions as well as in improving animal health, growth performance, and disease resistance;
• Development of probiotic-containing foods, beverages, and dietary supplements for human and animal consumption;
• Development of probiotics for soil and plant health.

Dr. Alessandra Pino
Dr. Mutamed Ayyash
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Applied Microbiology applmicrobiol	-	2.8	2021	13.3 Days	CHF 1200	Submit
Fermentation fermentation	3.3	5.7	2015	15.5 Days	CHF 2100	Submit
Foods foods	5.1	8.7	2012	14.9 Days	CHF 2900	Submit
Microbiology Research microbiolres	2.2	2.8	2010	20.7 Days	CHF 1600	Submit
Microorganisms microorganisms	4.2	7.7	2013	15.2 Days	CHF 2700	Submit
Nutrients nutrients	5.0	9.1	2009	12.9 Days	CHF 2900	Submit

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Published Papers (1 paper)

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All Applied Microbiology Fermentation Foods Microbiology Research Microorganisms Nutrients

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19 pages, 1446 KiB  

Open AccessReview

Postbiotics Derived from Lactic Acid Bacteria Fermentation: Therapeutic Potential in the Treatment of Muscular Complications in Inflammatory Bowel Disease

by Emili Bruna Toso Bueno, Kimberlly de Oliveira Silva, Maria Eduarda Ferraz Mendes, Lívia Batista de Oliveira, Felipe Prado de Menezes, Anna Cardoso Imperador, Lucimeire Fernandes Correia and Lizziane Kretli Winkelstroter

Fermentation 2025, 11(7), 362; https://doi.org/10.3390/fermentation11070362 - 23 Jun 2025

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Abstract

Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gastrointestinal tract, which can result in several muscular complications, including sarcopenia, the loss of muscle mass, and impaired muscle function. Recently, postbiotics derived from lactic bacteria, such as Lactobacillus and Bifidobacterium, [...] Read more.

Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gastrointestinal tract, which can result in several muscular complications, including sarcopenia, the loss of muscle mass, and impaired muscle function. Recently, postbiotics derived from lactic bacteria, such as Lactobacillus and Bifidobacterium, have emerged as potential therapeutic modulators for these complications. Postbiotics are bioactive metabolites, such as short-chain fatty acids (SCFAs), antimicrobial peptides, and other compounds produced by microorganisms during fermentation, which have anti-inflammatory, antioxidant, and metabolic regulatory effects. These metabolites are important due to their potential to positively influence muscle health in patients with IBD, mainly by reducing systemic and local inflammation, improving gut microbiota, and modulating muscle metabolism. Studies suggest that these postbiotics may help minimize muscle degradation and promote muscle tissue regeneration, assisting in the prevention or management of IBD-associated sarcopenia. Despite the promising results, challenges remain, such as variability in postbiotic production and the need for further clinical studies to establish clear therapeutic guidelines. This review article explores the mechanisms of action of postbiotics derived from lactic acid bacteria and their potential applications in the treatment of muscle complications in patients with IBD, highlighting future therapeutic perspectives. Full article

(This article belongs to the Topic News and Updates on Probiotics)

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