Search Results (493)

During tendon healing, collagen III expression precedes that of collagen I. The collagen I-to-III ratio at a certain time point post-laceration serves as an indicator of the healing status. Consequently, it is crucial to understand how different therapeutic approaches to support tendon healing affect the collagen I-to-III ratio in the extracellular matrix of a healing tendon, particularly across distinct anatomical zones. We compared the impact of a platelet-derived growth factor-BB (PDGF-BB) treatment via controlled release from coaxially electrospun DegraPol^® (Ab medica, Cerro Maggiore, Italy) hollow-fiber mesh with a treatment by the vehicle alone (no PDGF-BB) in the rabbit Achilles tendon full transection model and provide data on the collagen I-to-III ratio 3 weeks post-operation. For this purpose, we compared a dual-color Herovici staining to two single IHC labeling, for collagen I and collagen III, respectively. Herovici staining (HV) was expected to offer a more precise approach (pink-to-blue histogram) than the two separately labeled IHC stainings, both with chromogenic DAB labeling (red-to-green histogram), despite an anticipated positive correlation of the data assessed by these methods. Different zones were compared, i.e., native tendon tissue, reactive zone at interface to implant, hot zone within the core of the healing tendon and the zone within the scaffold, meaning the collagen deposited within the fibers of the implanted DegraPol^® tube, respectively. The analysis revealed that the ratios obtained via HV correlated weakly with the ratios obtained by IHC. Based on HV, PDGF-BB therapy led to higher collagen I-to-III ratios in all zones, except for the zone within the scaffold pores, while IHC did not reveal significant differences. Notably, collagen I-to-III ratios were not higher in immediate proximity, but rather distal from the PDGF-BB releasing implant, specifically in the core of the healing tendon tissue. Hence, a PDGF-BB therapy is suggestive of greater collagen maturation in specific zones of the healing tendon. Full article

Siliceous rocks of various colors and types are extensively developed within the Middle–Lower Ordovician carbonate along the Northwest Tarim Basin. Their genesis provides important insights into the evolution of basinal fluids and the associated diagenetic alterations of the carbonates. Based on petrographic, geochemical, fluid inclusion, and petrophysical analyses, this study investigates the origin of siliceous rocks within the Middle–Lower Ordovician carbonate formations (Penglaiba, Yingshan, and Dawangou formations) in the Kalpin area, Tarim Basin, and investigates the impact on hydrothermal reservoirs. The results reveal two distinct episodes of siliceous diagenetic fluids: The first during the Late Ordovician involved mixed hydrothermal fluids derived from deep magmatic–metamorphic sources, formation brines, and seawater. Characterized by high temperature and moderate salinity, it generated black chert dominated by cryptocrystalline to microcrystalline quartz through replacement processes. The second episode developed in the Middle–Late Devonian as a mixture of silicon-rich fluids from deep heat sources and basinal brines. In conditions of low temperature and high salinity, it generated gray-white siliceous rocks composed of micro- to fine crystalline quartz, spherulitic-fibrous chalcedony, and quartz cements via a combination of hydrothermal replacement and precipitation. A reservoir analysis reveals that the multi-layered black siliceous rocks possess significant reservoir potential amplified by the syndiagenetic tectonic fracturing. In contrast, the white siliceous rocks, despite superior petrophysical properties, are limited in scale as they predominantly infill late-stage fractures and vugs, mainly enhancing local flow conduits. Hydrothermal alteration in black siliceous rocks is more intense in dolostone host rocks than in limestone. Thus, thick (10–20 m), continuous black siliceous layers in dolostone and the surrounding medium-crystalline dolostone alteration zones, are promising exploration targets. This study elucidates the origins of Ordovician siliceous rocks and their implications for carbonate reservoir properties. The findings may offer valuable clues for deciphering the evolution and predicting the distribution of hydrothermal reservoirs, both within the basin and in other analogous regions worldwide. Full article

This study evaluates the feasibility of establishing a new strawberry cultivation zone in the Region of Florina, Northern Greece, as a strategy to support rural revitalization and agricultural diversification. Day-neutral strawberry genotypes were cultivated under net-house conditions at the University of Western Macedonia and assessed for physiological traits (SPAD index, chlorophyll fluorescence) and fruit quality (weight, color, firmness, °Brix, titratable acidity); while postharvest behavior was evaluated after seven days of cold storage. Statistical analysis identified genotypes with superior physiological performance and storability. Preliminary economic analysis suggests that their adoption could increase growers’ income by 20–30% compared to conventional varieties. The findings support the development of a strawberry production zone in Florina, with broader implications for sustainable agricultural intensification and rural development in underutilized European regions. Full article

Urban expansion causes increasing risks to archaeological heritage and yet few studies have systematically analyzed multi-site urban change using consistent temporal datasets and standardized methods. In this sense, this study addresses this gap by applying a multi-temporal urban change detection framework to the Memphis region, focusing on the Abu Gurab, Abusir and Saqqara sites. To conduct this research, high-resolution satellite imagery from 2004, 2008 and 2025 was processed using harmonized geospatial classification and overlay techniques to quantify built-up area growth and identify zones where modern development threatens key monuments to include the Sun Temples of Userkaf and Nyuserre, and the pyramids of Sahure, Neferirkare and Neferefre. A GIS- and remote sensing-based workflow, combining supervised classification, post-classification comparison and buffer zone analysis, enabled precise monitoring of urban encroachment. Additionally, high-resolution imagery and in situ inspections supported detailed decay mapping of select monuments, using grayscale normalization and false-color analysis to quantify surface deterioration objectively. This approach highlights the progressive impact of urbanization on archaeological structures and provides actionable data for archaeological sites management. Finally, the results contribute to heritage risk assessment, support evidence-based conservation planning, and inform urban planning strategies in line with Sustainable Development Goal 11.4 and the UNESCO Historic Urban Landscape Recommendation (HULR). Full article

Training system selection critically influences peach orchard productivity through its effects on canopy light environment, physiological responses, and fruit quality. This study evaluated two contrasting training systems: a 2D planar fruiting wall system (Four-Axis, 1020 trees ha⁻¹) versus a 3D Quad-V system (590 trees ha⁻¹) using two peach cultivars, fresh table ‘Platibelle’ and clingstone ‘Mirel’ in Central Macedonia, Greece. Comprehensive physiological measurements including leaf gas exchange, chlorophyll fluorescence, and fruit quality parameters were assessed across two canopy zones (lower 0–1.2 m vs. upper 1.8–3.3 m) during the 2023 and 2024 growing seasons. Results demonstrated that the 2D system achieved superior leaf area index (LAI), but lower light interception, leading to enhanced photosynthetic performance with 15–20% higher net photosynthetic rates and improved water-use efficiency compared to the 3D system. Notably, the photosynthetic apparatus of fruiting wall trees maintained significantly greater efficiency (6.26 μmol CO₂ m⁻² s⁻¹) in the lower canopy zone than in Quad-V trees (3.6 μmol CO₂ m⁻² s⁻¹), indicating a more uniform and functional light environment. The 2D system produced fruits with improved flesh firmness and color development in ‘Mirel’, while higher dry matter in ‘Platibelle’. Correlation analysis revealed that Four-Axis trees enhanced the interdependence among thermal, gas exchange, and compositional traits, reflecting a shift from morphology-driven to metabolically integrated canopy function. In terms of yield, fruiting walls achieved higher efficiency and total production (Mt ha⁻¹) in ‘Mirel’, supporting their adoption to enhance productivity and peach fruit quality in Mediterranean conditions. Full article

A lateral flow immunoassay (LFIA) utilizing two types of marker conjugates—magnetite nanoparticles (MNPs) with specific antibodies and gold nanoparticles (GNPs) with anti-species antibodies—was proposed and realized for the detection of the pesticide paraquat. In this assay, the MP conjugate is used to concentrate the target analyte from the tested sample and then to form labeled immune complexes at the test strip, while the GNP conjugate is then applied for the integration into the formed complexes in the binding zone. The magnetic preconcentration allows for working with large volumes of samples, and the following treatment by the GNP conjugate enhances the coloration by five times for reliable analyte revelation in lower concentrations. In the course of the assay implementation, its conditions have been optimized, and the efficiency of the paraquat determination in orange samples was confirmed. The achieved detection limits were 1.2–3.7 ng/mL for visual assessment and 0.12–0.48 ng/mL for the instrumental one, with paraquat detection rates ranging from 96% to 120%. The implementation of the assay in combination with the stage of magnetic concentration allows for the collection of paraquat from large volumes of samples and detects it in this way in concentrations up to two orders of magnitude smaller. Full article

Color in urban public spaces is often approached as an aesthetic issue, yet it also governs psychological responses, legibility and safety, place identity, and environmental performance. Despite three decades of research, planners and designers still lack measurable, audit-ready guidance that links color decisions to verifiable outcomes. This paper presents a systematic review that consolidates evidence from environmental psychology, architecture and urban design, cultural studies, and building and urban physics. Studies were screened for outdoor or outward-facing settings and for explicitly reported color variables and performance indicators. The findings are organized into four domains in which color operates as a system variable: psychological and physiological effects; cultural expression and place identity; functional zoning and wayfinding; and sustainability and environmental adaptation. Across these domains, the review identifies robust patterns—such as the central role of luminance and saturation in shaping affect, attention, and visibility—while highlighting where outcomes are strongly conditioned by cultural, climatic, and material context. On this basis, the paper proposes an Objective–Strategy–Metric–Validation (OSMV) framework that connects design objectives to color strategies, quantitative metrics (e.g., color difference, contrast, and reflectance measures), and procedures for simulation or field validation. Framed in this way, color emerges not as a decorative accessory but as a measurable design variable that can be integrated into performance-based planning, regulation, and multi-objective optimization of urban public spaces. Full article

Bangladesh generates approximately 3000 tons of plastic waste daily, and high mismanagement leads to substantial discharge into soils, rivers, and oceans. Limited research exists on plastic pollution along Cox’s Bazar in southeastern Bangladesh, with no studies spanning the entire coast; this study provides the first comprehensive assessment of the full coastline. This study investigates the abundance, types, and distribution of macro-, meso-, and microplastics in sediments from 23 stations covering Tourism, Active, and Less Active areas. Plastics were classified by size, shape, color, and polymer composition using stereomicroscopy and Fourier Transform Infrared Spectroscopy (FTIR), while spatial patterns of microplastic polymers were analyzed using Inverse Distance Weighted (IDW) interpolation. A total of 11,558 plastic particles were identified, with microplastics dominating (409.04 particles/m²), followed by mesoplastics (60.7 particles/m²) and macroplastics (32.8 particles/m²). Expanded polystyrene (EPS) and fragments were the most prevalent shapes, while transparent-white particles dominated in color. Polystyrene (PS), polypropylene (PP), and polyethylene (PE) comprised over 95% of polymers. IDW mapping highlighted Tourism, urban, and industrial zones as microplastic hotspots, with higher abundances in tourism areas. These findings provide a baseline for monitoring coastal plastic pollution and emphasize improved plastic management and recycling, contributing globally to understanding contamination in rapidly urbanizing, tourism-driven developing regions. Full article

Interior space quality in certified office buildings is key in supporting the health and well-being of occupants. Daylight, which regulates the human circadian rhythm and affects physiological processes and productivity, is crucial. This study’s objective was to determine how a building’s architecture and selected elements of its interior such as partitions and finishing material parameters affect sunlight distribution in workspaces and its biological effectiveness, as measured using Equivalent Melanopic Lux (EML). The environment’s impact on the non-visual potential of a space was also assessed (in relation to the M/P ratio). To achieve these objectives, we used a 3D model of an office building floor to simulate natural lighting in various configurations, for a cool temperate climate using Solemma’s ALFA 2025 software. This research was conducted using simulations only, with no in situ measurements. The study assessed melanopic light intensity for specific zones and workstation groups. The impact of ceiling colors and the five colors given to partitions of different heights located between desks was also determined. The study evaluated the relationship between photopic and melanopic intensity and found that, as the height of the partitions increased, especially with cloudy skies, the importance of these planes’ colors increased. Blues had a positive effect on the space’s non-visual potential, while oranges showed significant decreases in EML relative to lux, by up to 25%. This research underscores the importance of light’s non-visual impact and the consideration of these aspects at every design stage, especially interior design, to provide a comfortable work environment and its long-term benefits. We also proposed natural light exposition optimization strategies that can support proper circadian rhythm. Full article

As urbanization accelerates, children’s safety when crossing urban streets has become an increasingly prominent concern. However, current street designs and visual guidance facilities are largely configured around adult users and tend to overlook children’s distinct cognitive and perceptual characteristics. In this study, we used seven virtual reality (VR) street-crossing scenarios and combined questionnaires, eye tracking, and motion capture to evaluate how five types of visual guidance elements—Footprint (stop) markings and Traffic bollard, Color-Coded Arrows, Look left markings, Tactile Paving Patterns, and Stop line—affect children’s street-crossing behavior. The results show that Footprint (stop) markings and Traffic bollard clearly enhance children’s Stopping–Scanning Awareness, prompting them to slow down and briefly pause within the decision zone. The Look left markings provide only limited cues for Left–Right Scanning in both adults and children. Tactile Paving Patterns and Color-Coded Arrows effectively attract children’s visual attention, but may weaken their judgement of street-crossing risk. The Stop line strengthens the visual boundary and increases environmental monitoring awareness among all participants; however, this study did not observe a clear improvement in Gait variability. By extending theories of children’s traffic behavior, this study also highlights that some facilities labeled as “child-friendly” may be over-designed or cognitively misaligned with children’s actual perceptual and decision-making processes. These findings provide empirical evidence for optimizing street facilities and for developing related technical standards and public policies. Full article

Ocean color remote sensing is important for monitoring marine biogeochemical processes. The accuracy of remote sensing reflectance (R_rs), a fundamental data product, is critical yet challenged by the scale mismatch between in situ point measurements and satellite-based areal observations from pixels. This mismatch introduces uncertainty, notably from the non-uniform spatial response within a pixel—a potential error source at pixel boundaries that remains poorly quantified. To address this issue, we introduced the pixel-level spatial mismatch index (PSMI) to assess spatial representativeness errors induced by the pixel boundary effect (PBE). Using AERONET-OC (AErosol RObotic NETwork-Ocean Color) data alongside MODIS/Aqua and OLCI/Sentinel-3A observations, we showed that the PSMI effectively identified a systematic R_rs deviation peak when a site lay within a pixel’s edge attenuation zone. This phenomenon, observed across sensors with different resolutions (MODIS and OLCI), exhibited sensor- and band-dependent peak characteristics. We further proposed a quantitative framework called a Riemann Stieltjes integral-based index to measure the spatial concentration of this deviation peak, and a baseline method to objectively define the PBE window. Our analyses revealed that PBE not only acts as an independent error source but also interacts with atmospheric and geometric errors, forming new multifactor interactions that significantly modulate the overall uncertainty in R_rs products. Consequently, pixel-scale effects should be incorporated into future validation protocols, and the PSMI framework can provide an intrinsic tool for this purpose. Full article

Stenocereus fruits are appreciated for their flavor and color, and their cultivation is highly sustainable, as they grow in arid zones without the need for fertilizers or agrochemicals. However, their nutritional and bioactive composition remains underexplored. This study evaluated the physicochemical and nutritional properties, bioactive compound content, and antioxidant capacity (AOX) of Stenocereus thurberi (red, white, purple, and orange), Stenocereus martinezzi (red), and Stenocereus gummosus (red). All fruits exhibited low total soluble solids (12.6 ± 0.2–14.7 ± 0.3 °Brix), acidity (0.81 ± 0.03–1.12 ± 0.03%), and moderate dietary fiber content (3.71 ± 0.05–4.86 ± 0.09%). S. martinezzi stood out for its high levels of betalains (33.7 ± 0.65 mg/100 g_fw), vitamin E (84.7 ± 0.2 µg/100 g_fw), and vitamin C (147.6 ± 11.4 mg/100 g_fw). At the same time, potassium, magnesium, and calcium were the predominant minerals in all samples. S. gummosus showed the highest total soluble phenols (120.6 ± 2.2 mg/100 g_fw) and was also notable for its flavonoid content. Flavonoids, hydroxycinnamic, and hydroxybenzoic acids were detected in all fruits. Red fruits had the highest AOX levels, followed by white, orange, and purple varieties. In conclusion, these fruits are nutritious, low in sugars, and rich in bioactive compounds, suggesting their potential as functional foods, particularly beneficial for individuals with chronic degenerative diseases. Full article

From the perspective of children’s emotional behavior, this study constructs a multidimensional indicator framework—“spatial elements-spatial typologies-spatial color-emotion and behavior.” Integrating behavior mapping, we employ deep- and machine-learning models to quantify the pathways through which primary-school campus spaces shape children’s emotional and behavioral responses. The results indicate that: (1) individual external spatial elements exert a more pronounced influence on children’s emotions; (2) different spatial typologies show marked disparities in emotional activation, characterized by polarization and clustering at low levels, revealing common shortcomings in current campus construction; (3) the emotional effects of spatial color diverge systematically by gender and age, with differentiation intensifying as age increases; and (4) overlay analyses of behavior maps corroborate associations between external natural spaces, key internal functional zones, and children’s behavioral patterns and affective responses. Building on these findings, the study proposes targeted optimization strategies oriented toward children’s emotional experience and behavioral development, providing data-driven support for the affective design of primary-school campuses. Full article

Heat-treated wood is widely used for its eco-friendliness and aesthetic appeal. However, it is prone to fading under ultraviolet (UV) radiation, which diminishes its decorative effect and shortens its service life. To clarify the performance evolution and degradation mechanisms of heat-treated wood, Chinese fir, treated at 190 °C under vacuum, was subjected to artificial weathering, and the dynamic changes in surface appearance, chemical composition, and microstructure were monitored. The results show that after artificial weathering, both heat-treated and untreated wood exhibited similar surface color change trends, characterized by darkening, yellowing, and reddening, but heat treatment significantly inhibited surface color changes. After 372 h of weathering, the total color change of heat-treated wood (ΔE = 24.05) was smaller than that of the untreated wood (ΔE = 37.78), and its yellowness index (b* = 58.93%) was also far lower than the untreated group (b* = 119.85%). Additionally, the gloss of heat-treated Chinese fir increased by 17% during weathering. However, as weathering progressed, the protective effect of heat treatment on the appearance gradually weakened, and it could not prevent long-term structural breakdown. The improved color stability is closely linked to condensed lignin and unsaturated phenolic chromophores, while the preferential thermal decomposition of hemicelluloses creates “weathering-vulnerable zones”. This study provides both a theoretical basis for understanding the weathering behavior of heat-treated wood and practical guidance for optimizing wood protection technologies. Full article

Tourmalines from the Anjanabonoina pegmatite field, Central Madagascar, exhibit some of the most complex multi-color zoning patterns known. These tourmalines are also rare because of their unusual Ca- and Li-rich liddicoatite composition. Liddicoatite specimens crystallize in miarolitic pockets in pegmatites, which periodically break open and seal. Multivariate analysis of Laser-Induced Breakdown Spectroscopy (LIBS) spectra of an Anjanabonoina liddicoatite specimen allows evaluation of simultaneous changes in all elements during crystallization. LIBS is an optical emission technique in which photons emitted from a cooling laser plasma are diffracted and recorded as a spectrum. All elements present in the sample at concentrations above their inherent detection limits are represented by peaks in the spectrum. Principal Component Analysis of 123 LIBS spectra acquired in a core-to-rim traverse reveals six major compositional zones that suggest four stages of crystallization, the last three of which begin with the opening of the pocket and mixing of pegmatitic fluids with those from the metasedimentary host rocks. Full article