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Article

5 Citations

9,497 Views

14 Pages

Type XVIII Collagen Modulates Keratohyalin Granule Formation and Keratinization in Oral Mucosa

Ha Thi Thu Nguyen,
Mitsuaki Ono,
Emilio Satoshi Hara,
Taishi Komori,
Midori Edamatsu,
Tomoko Yonezawa,
Aya Kimura-Ono,
Kenji Maekawa,
Takuo Kuboki and
Toshitaka Oohashi

Int. J. Mol. Sci.2019, 20(19), 4739;https://doi.org/10.3390/ijms20194739

24 September 2019

Epithelial keratinization involves complex cellular modifications that provide protection against pathogens and chemical and mechanical injuries. In the oral cavity, keratinized mucosa is also crucial to maintain healthy periodontal or peri-implant t...

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Article

6,868 Views

16 Pages

Similar Ehlers–Danlos Syndrome Profiles Produced by Variants in Multiple Collagen Genes

Sahil S. Tonk and
Golder N. Wilson

DNA2025, 5(1), 11;https://doi.org/10.3390/dna5010011

25 February 2025

Background: Despite increased attention to double-jointedness or joint hypermobility as seen in connective tissue dysplasias like Ehlers–Danlos syndrome, improved clinical DNA correlations are needed to reduce decadal delays in diagnosis. Metho...

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Article

28 Citations

5,833 Views

15 Pages

Endostatin Stimulates Proliferation and Migration of Myofibroblasts Isolated from Myocardial Infarction Model Rats

Akira Sugiyama,
Yuka Hirano,
Muneyoshi Okada and
Hideyuki Yamawaki

Int. J. Mol. Sci.2018, 19(3), 741;https://doi.org/10.3390/ijms19030741

6 March 2018

Myofibroblasts contribute to the healing of infarcted areas after myocardial infarction through proliferation, migration, and production of extracellular matrix (ECM). Expression of endostatin, a cleaved fragment of type XVIII collagen, increases in...

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Article

5 Citations

3,879 Views

16 Pages

The Effect of Carnosine on UVA-Induced Changes in Intracellular Signaling of Human Skin Fibroblast Spheroids

Gilda Aiello,
Francesca Rescigno,
Marisa Meloni,
Beatrice Zoanni,
Giancarlo Aldini,
Marina Carini and
Alfonsina D’Amato

Antioxidants2023, 12(2), 300;https://doi.org/10.3390/antiox12020300

28 January 2023

Dermis fibroblasts are very sensitive to penetrating UVA radiation and induce photo-damage. To protect skin cells against this environmental damage, there is an urgent need for effective compounds, specifically targeting UVA-induced mitochondrial inj...

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Article

1 Citations

1,969 Views

21 Pages

CX3CR1–Fractalkine Dysregulation Affects Retinal GFAP Expression, Inflammatory Gene Induction, and LPS Response in a Mouse Model of Hypoxic Retinopathy

Colin Rorex,
Sandra M. Cardona,
Kaira A. Church,
Derek Rodriguez,
Difernando Vanegas,
Reina A. Saldivar,
Amira El-Sheikh,
Yufeng Wang,
Stefka Gyoneva and
Anne C. Cotleur
+ 1 author

Int. J. Mol. Sci.2025, 26(3), 1131;https://doi.org/10.3390/ijms26031131

28 January 2025

Diabetic retinopathy (DR) causes vision loss due to sustained inflammation and vascular damage. The vascular damage is evident by fibrinogen leakage, angiogenesis, and hypoxia. Neuronal regulation of microglia via the CX3CL1 (Fractalkine or FKN)-CX3C...

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