Search Results (1,555)

Optimising spraying operations in coffee cultivation can enhance both application efficiency and effectiveness. However, no studies have specifically assessed droplet deposition on leaves adjacent to the spray application band—fraction of droplet deposition referred to as ‘transfer’ in this study. Therefore, this study aimed to quantify droplet deposition and transfer resulting from different application rates and nozzle types in coffee trees. The experiment was conducted in a factorial design including three application rates (200, 400, and 600 L ha⁻¹) and two nozzle types (hollow cone and flat fan), with four replicates. Deposition was quantified at multiple positions: two application sides (left and right), three sections of the plant (upper, middle, and lower), and two branch positions (inner and outer). Thus, all measurements across sides, plant sections, and branch positions were nested, resulting in correlated data that were analysed using linear mixed-effects models (lme4 package), with parameters estimated using the restricted maximum likelihood method. The flat fan nozzle achieved the highest reference deposition, particularly on outer canopy thirds, while spray transfer (~29% of total deposition) was mainly driven by operational factors. Hollow cone nozzles at 200 L ha⁻¹ minimized transfer while maintaining adequate deposition. Optimizing applications requires maximizing reference deposition and minimizing transfer, which can be achieved through operational adjustments, airflow management, and complementary strategies such as adjuvants, electrostatic spraying, or tunnel sprayers. Full article

This study presents the evaluation of the photometric performance and energy-saving potential of light-coloured pavement mixtures (LCPMs) in road lighting applications, along with their effects on surface friction, macrotexture, and specularity. The application of LCPMs in tunnels can enhance road surface illumination, thereby improving driver visibility, increasing road safety and comfort, and reducing energy consumption per kilometre. While such surface treatments enable more efficient and cost-effective lighting, maintaining an optimal balance in surface performance poses many challenges due to the impact on concurrent targets in terms of friction, macrotexture, noise contribution, and specularity. Indeed, issues related to friction performance, macrotexture characteristics, and the concurring energy-saving potential of LCPMs remain insufficiently explored. To this end, investigations were conducted to assess the energy-saving potential of light-coloured surface treatments and to evaluate the photometric, frictional, and macrotexture properties of different densely graded LCPMs. A new method was set up and implemented to compare different surface treatments. The results indicate that light-coloured surface treatments increased the average luminance coefficient (up to 0.2406), with glass-containing mixtures offering greater potential for improved surface texture, friction, and energy-efficient road lighting. Full article

Multilayer heterostructures of [(BiFeO₃)_m/(SrTiO₃)_n]_p were synthesized on ITO-coated quartz substrates via pulsed laser deposition, with varying thickness ratios (r = n/m) and periodicities (p = 1–3). Structural, electrical, and piezoelectric properties were systematically investigated using X-ray diffraction, AFM, and PFM. The BiFeO₃ layers crystallized in a distorted rhombohedral phase (R3c), free of secondary phases. Compared to single-layer BiFeO₃ films, the multilayers exhibited markedly lower leakage current densities and enhanced piezoelectric response. Electrical conduction transitioned from space-charge-limited current at low fields (E < 100 kV/cm) to Fowler–Nordheim tunneling at high fields (E > 100 kV/cm). Optimal performance was achieved for r = 0.30, p = 1, with minimal leakage (J = 8.64 A/cm² at E = 400 kV/cm) and a peak piezoelectric coefficient (d₃₃ = 55.55 pm/V). The lowest coercive field (Ec = 238 kV/cm) occurred in the configuration r = 0.45, p = 3. Saturated hysteresis loops confirmed stable ferroelectric domains. These findings demonstrate that manipulating layer geometry in [(BiFeO₃)_m/(SrTiO₃)_n]_p stacks significantly enhances functional properties, offering a viable path toward efficient, lead-free piezoelectric nanodevices. Full article

Background/Objectives: This study was designed to investigate the potential clinical, biochemical, haematological, and pathological associations of carpal tunnel syndrome through a multidisciplinary approach encompassing the fields of internal medicine, gastroenterology, and neurology. Methods: The study group (CTS-positive) comprised 265 patients who presented with dyspeptic complaints and underwent upper gastrointestinal endoscopy, gastric antrum biopsy, electromyography, and comprehensive biochemical and haematological analyses. A control group of 265 patients with similar symptoms but without CTS was selected for comparison. A comparative analysis was conducted on clinical findings, gastric biopsy results, and biochemical and haematological parameters. Results: There were no significant differences in age, gender distribution, or gastric biopsy findings (Helicobacter pylori, intestinal metaplasia, atrophy, and dysplasia) between the CTS-positive and CTS-negative groups. However, significant biochemical differences were identified, including elevated calcium and reduced magnesium levels in CTS-positive patients. Haematological evaluations revealed higher lymphocyte, eosinophil, basophil, erythrocyte, haemoglobin, and haematocrit levels, along with reduced neutrophil-to-lymphocyte ratios and red blood cell distribution widths in the CTS-positive group. Further analysis in the form of correlation and logistic regression analyses provided further confirmation of the association of elevated calcium, haemoglobin, and lymphocyte levels with increased risk of CTS. Conclusions: This multidisciplinary study identifies significant associations between CTS and specific biochemical and haematological parameters, notably calcium-magnesium imbalance and erythrocyte indices. These findings suggest underlying biological interactions that may guide future diagnostic and therapeutic strategies for patients with carpal tunnel syndrome. Full article

Hydrogen bonding, a prevalent molecular interaction in nature, is crucial in biological and chemical processes. The emergence of single-molecule techniques has enhanced our microscopic understanding of hydrogen bonding. However, it is still challenging to track the dynamic behaviour of hydrogen bonding in solution, particularly under physiological conditions where interactions are significantly weakened. Here, we present a nanoscale-confined, functionalised quantum mechanical tunnelling (QMT) probe that enables continuous monitoring of electrical fingerprints of single-molecule hydrogen bonding interactions for over tens of minutes in diverse solvents, including polar physiological solutions, which reveal reproducible multi-level conductance distributions. Moreover, the functionalised QMT probes have successfully discriminated between L(+)- and D(−)-tartaric acid enantiomers by resolving the conductance difference. This work uncovers dynamic single-molecule hydrogen bonding processes within confined nanoscale spaces under physiological conditions, establishing a new paradigm for probing molecular hydrogen-bonding networks in supramolecular chemistry and biology. Full article

Urban deep excavations conducted near operational tunnels necessitate stringent deformation control. This study investigates the Baiyun Station excavation by employing a three-dimensional finite-element model based on the Hardening Soil Small-strain (HSS) constitutive law, calibrated using Phase I field monitoring data on wall deflection, ground settlement, and tunnel displacement. Material parameters for the HSS model derived from the prior Phase I numerical simulation were held fixed and used to simulate the Phase II excavation, with peak errors of less than 5.8% for wall deflection and less than 2.9% for ground settlement. The model was subsequently applied to evaluate the impacts of Phase II excavation. The key contribution of this study is a monitoring-driven HSS modeling framework that integrates staged excavation simulation with field-based calibration, enabling quantitative assessment of tunnel responses—including settlement troughs, bow-shaped wall deflection patterns, and the distance-decay characteristics of lining displacement—to support structural safety evaluations and protective design measures. The results demonstrate that the predicted deformations and lining stresses in adjacent power and metro tunnels remain within permissible limits, offering practical guidance for excavation control in densely populated urban areas. Full article

Fruit production is a high environmental impact sector, requiring sustainable strategies that reduce greenhouse gas (GHG) emissions, improve resource efficiency, and maintain fruit quality. This study assessed the environmental performance of innovative substrates with biodegradable additives and organic binders in tunnel-grown raspberry production. The functional unit was 1 kg of marketable fruit, and the experiment was conducted in Karwia, Poland. GHG emissions were calculated for eight substrate variants following ISO 14040 and 14041 guidelines. The baseline was coconut fiber, while modified variants included the additions of sunflower husk biochar and/or a wood-industry isolate, representing sustainable strategies in soilless cultivation. Emissions ranged from 0.728 to 1.226 kg CO₂ eq/kg of raspberries, with the control showing the highest values. All modified substrates (produced based on a mixture of biochar and isolate) reduced emissions, with the most efficient variant achieving nearly a 40% decrease. Water use efficiency was decisive, as consumption declined from 2744 m³/ha (control) to 1838 m³/ha in improved variants. Substrate air–water properties proved critical for both environmental and economic outcomes. The findings confirm that substrate modification constitutes an effective, sustainable strategy for raspberry production under high tunnels, supporting climate-smart horticulture and resource-efficient food systems. Full article

Due to their high carrier mobility, thermal conductivity, and exceptional foldability, transition metal dichalcogenides (TMDs) present promising prospects in the realm of flexible semiconductor devices. Concurrently, tunneling field-effect transistors (TFETs) have garnered significant attention owing to their low energy consumption. This study investigates a TMD van der Waals heterojunction (VdWH) TFET, specifically by fabricating MoS₂ field-effect transistors (FETs), WSe₂ FETs, and MoS₂/WSe₂ VdWH TFETs. The N-type characteristics of the MoS₂ and P-type characteristics of WSe₂ are established through an analysis of the electrical characteristics of the respective FETs. Finally, we analyze the energy band and electrical characteristics of the MoS₂/WSe₂ VdWH TFET, which exhibits a drain current switching ratio of 10⁵. This study provides valuable insights for the development of novel low-power devices. Full article

Background: The consequences of median nerve compression at the carpal tunnel level require a precise diagnostic evaluation before a frequently applied surgical intervention. Positive Tinel or Phalen signs are not always related to abnormal results in electroneurographic examinations of sensory and motor nerve fibers, which are intended to confirm final diagnoses, thereby confusing both surgeons and neurophysiologists. In the face of contradictory data, this study aims to reinvestigate these correlations in a randomly chosen population of patients with a primary diagnosis of carpal tunnel syndrome (CTS). Methods: Seventy-five randomly chosen patients with clinically detected CTS underwent neurophysiological studies of median nerve sensory (SNAP) and motor (CMAP) fibers conduction at the wrist. Both the median and ulnar nerves were assessed to reduce the risk of misinterpretation related to anatomical variations. Results: This study provides evidence on the relatively high utility of Phalen’s test in the early clinical detection of CTS within a general population of patients, whose positive results moderately correlate (rho = −0.327) with abnormalities in amplitudes rather than the distal latency parameters of SNAP recordings. The axonal injury type is more distinct than slowing-down impulses at the wrist following compression of the sensory nerve fibers in the early course of CTS. Positive Tinel’s test results are useful in diagnosing CTS patients with advanced axonal and demyelinating changes in the motor fibers at the wrist, which weakly correlate with prolonged latency and decreased amplitude in SNAP recordings (rho = −0.214 and rho = −0.235, respectively), but not with abnormalities in recordings of both amplitudes and latencies in CMAP electroneurography. Conclusions: The correlations between clinical signs and neurophysiological findings in CTS indicate that provocative tests, such as Phalen’s and Tinel’s, have limited diagnostic value, demonstrating only weak-to-moderate associations with neural conduction parameters. A positive Tinel’s sign should be regarded mainly as a marker of severe or chronic sensory impairment, often accompanied by motor fibers involvement in advanced pathological stages, rather than as an indicator of motor damage alone. Nerve conduction studies remain essential for confirming CTS, assessing its severity, and guiding treatment decisions, including surgical qualification. The presented correlation of clinical and functional neurophysiological results in CTS diagnosis allows us not only to specify the source and severity of the pathology of the median nerve fibers but also may influence the personalization of physiotherapeutic and surgical treatments. Full article

Shotcrete used in underground structures like tunnels is susceptible to sulfate and chloride erosion. In order to systematically study the deterioration law and mechanism of the durability of high-performance shotcrete under a salt erosion environment, the durability test of high-performance shotcrete was carried out by an indoor long-term immersion test using a clear water solution, Na₂SO₄ solution, and Na₂SO₄ and NaCl mixed solution as erosion mediums. A comparative study was conducted on the effects of different curing time, erosion time, erosion medium, and erosion direction on the physical and mechanical properties and SO₄²⁻ content. The microstructure was analyzed to reveal the time evolution process and mechanism of the durability of high-performance shotcrete under coupled erosion. The results show the following: (1) The mass change rate of high-performance shotcrete under the action of coupling erosion increases first, then decreases, and then increases. The compressive strength of the surface perpendicular to the jet direction is better than that of the surface along the vertical jet direction. (2) The diffusion depth of SO₄²⁻ along the injection direction is larger, and the content of SO₄²⁻ is larger at the same depth. The existence of Cl⁻ delays the diffusion of SO₄²⁻ to a certain extent. (3) In the early stage of erosion, the corrosion expansion products generated by the external SO₄²⁻ entering the concrete will fill the original pores and cracks, which improves the durability of the concrete. In the late stages of erosion, the accumulation of corrosion products increases, which accelerates the deterioration of its durability. Full article

The greater wax moth Galleria mellonella (Lepidoptera: Galleriinae) represents a ubiquitous apicultural pest that poses significant threats to global beekeeping industries. The larvae damage honeybee colonies by consuming wax combs and tunneling through brood frames, consequently destroying critical hive infrastructure including brood-rearing areas, honey storage cells, and pollen reserves. Larval feeding behavior is critically dependent on chemosensory input for host recognition and food selection. In this study, we conducted a transcriptome analysis of larval heads and bodies in G. mellonella. We identified a total of 25 chemosensory genes: 9 odorant binding proteins (OBPs), 1 chemosensory protein (CSP), 5 odorant receptors (ORs), 4 gustatory receptors (GRs), 4 ionotropic receptors (IRs) and 2 sensory neuron membrane proteins (SNMPs). TPM normalization was employed to assess differential expression patterns of chemosensory genes between heads and bodies. Nine putative chemosensory genes were detected as differentially expressed, suggesting their potential functional roles. Subsequently, we quantified expression dynamics via reverse transcription quantitative PCR in major chemosensory tissues (larval heads, adult male and female antennae), revealing adult antennal-biased expression for most chemosensory genes in G. mellonella. Notably, two novel candidates (GmelOBP22 and GmelSNMP3) exhibited particularly high expression in larval heads, suggesting their crucial functional roles in larval development and survival. These findings enhance our understanding of the chemosensory mechanisms in G. mellonella larvae and establish a critical foundation for future functional investigations into its olfactory mechanisms. Full article

Background: Carpal tunnel syndrome is a common entrapment neuropathy of the upper limb that has a significant clinical and socioeconomic impact. Sonographic short-axis measurement of the median nerve cross-sectional area is a well-established complement to clinical examination and neurography. This study aimed to evaluate the correlation between the median nerve diameter ratio, distal motor latency, and sensory nerve conduction velocity. Methods: A total of 74 patients (94 hands and 93 evaluations) with carpal tunnel syndrome were examined. Ultrasound was performed using a Siemens Acuson X300 with a 10 MHz linear probe. Median nerve diameters proximal and within the carpal tunnel were measured in a longitudinal scan. The carpal tunnel ratio (proximal diameter/intratunnel diameter) was then calculated and correlated with distal motor latency. Results: No significant correlation was found between distal motor latency and the carpal tunnel ratio (r = 0.018, p = 0.8655). However, a weak, non-significant positive correlation was observed between sensory nerve conduction velocity and carpal tunnel ratio (r = 0.238, p = 0.326). Conclusions: Ultrasound cannot replace electrodiagnostic testing. In this cohort, no statistically significant association was observed between the carpal tunnel ratio and distal motor latency. While our findings do not support the use of this ultrasound parameter as a standalone diagnostic measure, sonographic assessment of the median nerve may still provide complementary information in selected clinical contexts. Full article

Accurately identifying surrounding rock failure modes and designing matching support systems are critical to the safety of deep-earth and underground space engineering. We develop a graded classification scheme based on the rock strength-to-stress ratio and the Stress Reduction Factor (SRF) to quantify failure types and guide support design. Within the convergence–confinement method (CCM) framework, we establish analytical models for shotcrete, rock bolts, steel arches, and composite support systems, enabling parameterized calculations of stiffness, load-bearing capacity, and equilibrium conditions. We conduct single-factor sensitivity analyses to reveal how the Geological Strength Index (GSI), burial depth (H), and equivalent tunnel radius (R₀) govern the evolution of surrounding rock pressure and deformation. We propose targeted reinforcement strategies that address large-deformation and high-stress instabilities in practice by linking observed or predicted failure modes to specific support schemes. A large-deformation case study verifies that the proposed parameterized design method accurately predicts the equilibrium support pressure and radial deformation, and the designed support scheme markedly reduces convergence. Accordingly, this study provides a practical tool for tunnel support parameter design and an analytical platform for safe, reliable, and efficient decision making for initial support. Full article

Objectives: This study aimed to evaluate the relationship between the median nerve cross-sectional area (CSA, mm²) and clinical findings, blood test results, and electrodiagnostic (EDX) measurements in patients with carpal tunnel syndrome (CTS). Methods: This cross-sectional study included 62 patients (111 hands). The median nerve CSA was assessed using ultrasound (US). The clinical assessment included symptom duration, symptom severity, the Boston Carpal Tunnel Questionnaire (BCTQ), and physical examination. Patient-level analyses used the CSA of the most symptomatic hand for clinical and laboratory variables (n = 62 patients). Hand-level EDX analyses accounted for within-patient clustering by reporting right and left hands separately. Associations were summarized with Spearman’s ρ and 95% confidence intervals (CIs); multiplicity was addressed using Benjamini–Hochberg false discovery rate (FDR). EDX units: latency ms, amplitude mV/µV, and velocity m/s. Results: CSA was not associated with global symptom burden (Visual Analog Scale; BCTQ). No laboratory marker remained significant after FDR across the full panel. By contrast, CSA correlated with EDX impairment at the hand level with low-to-moderate effect sizes; for example, distal motor latency was positively associated with CSA on the right (ρ = 0.557, 95% CI 0.334–0.733) and left (ρ = 0.318, 95% CI 0.022–0.578). CSA also correlated positively with CTS EDX severity (right: ρ = 0.449, 95% CI 0.223–0.646; left: ρ = 0.354, 95% CI 0.071–0.609). Conclusions: Ultrasonographic CSA was associated with electrophysiologic impairment and was not associated with overall symptom burden; laboratory signals did not survive FDR control. Accordingly, CSA may serve as a complementary morphologic adjunct to clinical assessment and EDX, with limited utility as a stand-alone severity metric. Full article

The construction of urban underground space develops very fast, and tunnel intersection construction has become a common practice, attracting significant attention due to the associated deformation responses and risk control challenges. To systematically review the research landscape and cutting-edge developments in this field, this study conducts a comprehensive analysis based on 744 publications (1994–2025) from the Web of Science Core Collection using bibliometric methods. Firstly, through visual analyses of annual publication trends, journal distributions, and keyword co-occurrences, the study reveals the evolution and research hotspots of the past three decades. Subsequently, three core dimensions are explored in depth: deformation mechanisms and patterns, deformation analysis methods for ground and existing structures, and ground control and reinforcement techniques. The review highlights the following: (1) Research focus has shifted from single construction scenarios to the complex interactions among multiple tunnels, yet the cumulative deformation effects caused by repeated soil disturbances during sequential excavation remain inadequately understood. (2) The bidirectional coupling between existing tunnels and surrounding soil has become a major research focus and challenge. Particularly in the presence of high-stiffness structures, the “free-field” assumption in the commonly used two-stage method is being questioned, necessitating the development of more refined computational theories. (3) Optimization of construction schemes under complex conditions is key to disturbance control, but current research still lacks systematic multi-objective optimization approaches. In addition, this paper analyzes the current research status and future directions to enhance the deformation perception capability and control technologies in tunnel construction influence zones, thereby further improving the safety and intelligence level of tunnel construction. Full article