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Review

10 Citations

9,678 Views

28 Pages

Decoding Chiari Malformation and Syringomyelia: From Epidemiology and Genetics to Advanced Diagnosis and Management Strategies

Corneliu Toader,
Horia Ples,
Razvan-Adrian Covache-Busuioc,
Horia Petre Costin,
Bogdan-Gabriel Bratu,
David-Ioan Dumitrascu,
Luca Andrei Glavan and
Alexandru Vlad Ciurea

Brain Sci.2023, 13(12), 1658;https://doi.org/10.3390/brainsci13121658

30 November 2023

Chiari Malformation and Syringomyelia are neurosurgical entities that have been the subject of extensive research and clinical interest. Globally prevalent, these disorders vary demographically and have witnessed evolving temporal trends. Chiari Malf...

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Article

1,119 Views

17 Pages

Tandem Detethering: A Novel One-Stage Approach Combining Cervicothoracic Cord Release Followed by Filum Terminale Sectioning

Natalie Amaral-Nieves,
Emilija Sagaityte,
Belinda Shao,
Shailen Sampath,
Rahul Sastry,
Prakash Sampath,
Petra M. Klinge and
Deus Cielo

J. Clin. Med.2025, 14(20), 7169;https://doi.org/10.3390/jcm14207169

11 October 2025

Background/Objectives: We report a prospective series of five patients with symptomatic cervicothoracic spinal cord tethering from prior surgical interventions for acquired and congenital spinal pathologies. Each patient demonstrated incidental radio...

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Review

546 Views

14 Pages

Primary Intramedullary Spinal Melanocytomas: Case Report and Review of Clinical Features, Diagnosis, and Management

Gil Kimchi,
Samantha Varela,
Juan Pablo Zuluaga-Garcia,
Francisco Call-Orellana,
Esteban Ramirez Ferrer,
Romulo Augusto Andrade de Almeida,
Maria A. Gubbiotti,
Isabella C. Glitza,
Andrew J. Bishop and
Claudio E. Tatsui
+ 4 authors

J. Clin. Med.2025, 14(22), 8047;https://doi.org/10.3390/jcm14228047

13 November 2025

Objective: Intramedullary melanocytomas are extremely rare spinal cord tumors with distinct histopathological and imaging characteristics. This report reviews the literature on this pathology and presents a representative case study, highlighting asp...

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Review

998 Views

13 Pages

An FGFR1-Altered Intramedullary Thoracic Tumor with Unusual Clinicopathological Features: A Case Report and Literature Review

Sze Jet Aw,
Jian Yuan Goh,
Jonis M. Esguerra,
Timothy S. E. Tan,
Enrica E. K. Tan and
Sharon Y. Y. Low

Neuroglia2025, 6(4), 39;https://doi.org/10.3390/neuroglia6040039

4 October 2025

Background: Primary spinal gliomas are rare in the pediatric population. Separately, FGFR1 genomic aberrations are also uncommon in spinal cord tumors. We report a case of a previously well adolescent who presented with progressive symptoms secondary...

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Case Report

356 Views

14 Pages

Syringomyelia in the Course of Resection of Foramen Magnum Pathology: A Case Report with an Intriguing Therapeutic Solution and Systematic Review

Rafal Rajski,
Waldemar Kolodziej,
Tomasz Sobolewski,
Krzysztof Kandziora,
Tomasz Klepinowski,
Anna Latka,
Beata Labuz-Roszak,
Dariusz Latka and
Kajetan Latka

Brain Sci.2026, 16(1), 14;https://doi.org/10.3390/brainsci16010014

22 December 2025

Introduction: Syringomyelia is a rare disease of the spinal cord, and postoperative syringomyelia is an extremely rare complication. There are very few scientific reports on this subject in the literature, which is why we decided to review them and r...

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