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25 pages, 701 KB  
Article
Digital Technology for Cultural Experience: A Psychological Ownership Perspective on the Three-Path Model
by Yifei Gao, Shaowen Zhan and Dan Yuan
Sustainability 2026, 18(2), 962; https://doi.org/10.3390/su18020962 (registering DOI) - 17 Jan 2026
Abstract
Digital technology is profoundly transforming the experiential landscape of tourism. However, its application does not necessarily produce cultural experiences, creating a critical bottleneck that constrains the sustainable development of the cultural tourism industry and broader societal culture. To address this gap, this study [...] Read more.
Digital technology is profoundly transforming the experiential landscape of tourism. However, its application does not necessarily produce cultural experiences, creating a critical bottleneck that constrains the sustainable development of the cultural tourism industry and broader societal culture. To address this gap, this study introduces psychological ownership theory as an overarching explanatory framework. It constructs and validates an integrated model that examines how digital technology characteristics (interactivity and innovativeness) influence cultural experience through three parallel mediating pathways: cognitive evaluation (perceived usefulness and ease of use), scenario construction, and flow experience. Based on 540 visitor questionnaires, structural equation modeling validated the theoretical model. Findings reveal that the interactivity and innovation of digital technology jointly stimulate visitors’ psychological ownership through three parallel pathways. Specifically, technological innovativeness exhibited the strongest effect on perceived ease of use (β = 0.387, p < 0.001), while the indirect effect via the flow experience path was also significant (effect size = 0.036). This process stimulates visitors’ psychological ownership, ultimately leading to cultural experiences. The study systematically reveals the pathways through which digital technology empowers cultural experiences across three dimensions: as a rational tool, an emotional narrative medium, and an intrinsic psychological catalyst. It highlights that strategically allocating technological resources to cultivate visitors’ psychological ownership is crucial for driving high-quality industrial development. Furthermore, the research offers significant implications for cultural sustainability, suggesting that such internally motivated identification provides a more effective foundation for the living transmission of culture and socio-cultural sustainability than external regulations or imposed norms. Full article
34 pages, 3909 KB  
Article
Technology Empowers Emotions: How AR Technology Triggers Consumers’ Purchase and Spread Behavior Towards Intangible Cultural Heritage Brands
by Yi Sheng, Jiajia Zhao and Euitay Jung
Behav. Sci. 2026, 16(1), 134; https://doi.org/10.3390/bs16010134 (registering DOI) - 17 Jan 2026
Abstract
In recent years, the application of augmented reality digital technology in brands has transformed the way consumers interact with brands. This study focuses on the impact of augmented reality (AR) technology on consumption behavior and brand communication related to intangible cultural heritage products, [...] Read more.
In recent years, the application of augmented reality digital technology in brands has transformed the way consumers interact with brands. This study focuses on the impact of augmented reality (AR) technology on consumption behavior and brand communication related to intangible cultural heritage products, integrating the TAM and UTAUT2 theories to construct a research model. This study employed a time–location sampling method, utilizing SPSS and AMOS software for data analysis based on valid questionnaires completed by 305 AR-experiencing consumers in Changsha City, Hunan Province. Results indicate that the presence and novelty of AR technology significantly and positively influence consumers’ attitudes toward using AR technology, which in turn affects their purchase intent, social media sharing behavior, and brand attitudes. The study confirms that emotional factors and consumer perceptions play a guiding and decisive role in the new consumption reality enabled by AR technology. These research findings have practical significance and value for ICH brand building and AR marketing, demonstrating that AR is an effective means to enhance the visibility and influence of the ICH brand. They inject new vitality into promoting more sustainable ICH protection and popularization, as well as the development of the digital creative industry. Full article
15 pages, 1053 KB  
Article
Training and Competency Gaps for Shipping Decarbonization in the Era of Disruptive Technology: The Case of Panama
by Javier Eloy Diaz Jimenez, Eddie Blanco-Davis, Rosa Mary de la Campa Portela, Sean Loughney, Jin Wang and Ervin Vargas Wilson
Sustainability 2026, 18(2), 958; https://doi.org/10.3390/su18020958 (registering DOI) - 17 Jan 2026
Abstract
The maritime sector is undergoing a profound transformation driven by disruptive technologies and global decarbonization objectives, placing new demands on Maritime Education and Training (MET) systems. Equipping maritime professionals with competencies for low-carbon shipping is now as critical as technological advancement itself. This [...] Read more.
The maritime sector is undergoing a profound transformation driven by disruptive technologies and global decarbonization objectives, placing new demands on Maritime Education and Training (MET) systems. Equipping maritime professionals with competencies for low-carbon shipping is now as critical as technological advancement itself. This study examines how disruptive technologies can be effectively integrated into MET frameworks to support environmental sustainability, using Panama as a representative case study of a major flag and maritime service state. A mixed-methods approach was adopted, combining a structured literature review, expert surveys, and a multi-criteria decision-making analysis based on the Analytic Hierarchy Process (AHP). The findings reveal a significant misalignment between existing MET curricula and the competencies required for decarbonized maritime operations. Key gaps include limited training in alternative fuels, emissions measurement and reporting, energy-efficient technologies, digital analytics, and regulatory compliance. Stakeholders also reported fragmented training provision, uneven access to emerging technologies, and weak coordination between academia, industry, and regulators, particularly in developing contexts. The results highlight the urgent need for curriculum reform and stronger cross-sector collaboration to align MET with evolving technological and regulatory demands. The study provides an applied, evidence-based framework for MET reform, with insights transferable to other systems facing similar decarbonization challenges. Full article
(This article belongs to the Special Issue Sustainable Energy Systems and Renewable Generation—Second Edition)
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25 pages, 2212 KB  
Article
Will AI Replace Us? Changing the University Teacher Role
by Walery Okulicz-Kozaryn, Artem Artyukhov and Nadiia Artyukhova
Societies 2026, 16(1), 32; https://doi.org/10.3390/soc16010032 (registering DOI) - 16 Jan 2026
Abstract
This study examines how Artificial Intelligence (AI) is reshaping the role of university teachers and transforming the foundations of academic work in the digital age. Building on the Dynamic Capabilities Theory (sensing–seizing–transforming), the article proposes a theoretical reframing of university teachers’ perceptions of [...] Read more.
This study examines how Artificial Intelligence (AI) is reshaping the role of university teachers and transforming the foundations of academic work in the digital age. Building on the Dynamic Capabilities Theory (sensing–seizing–transforming), the article proposes a theoretical reframing of university teachers’ perceptions of AI. This approach allows us to bridge micro-level emotions with meso-level HR policies and macro-level sustainability goals (SDGs 4, 8, and 9). The empirical foundation includes a survey of 453 Ukrainian university teachers (2023–2025) and statistics, supplemented by a bibliometric analysis of 26,425 Scopus-indexed documents. The results indicate that teachers do not anticipate a large-scale replacement by AI within the next five years. However, their fear of losing control over AI technologies is stronger than the fear of job displacement. This divergence, interpreted through the lens of dynamic capabilities, reveals weak sensing signals regarding professional replacement but stronger signals requiring managerial seizing and institutional transformation. The bibliometric analysis further demonstrates a theoretical evolution of the university teacher’s role: from a technological adopter (2021–2022) to a mediator of ethics and integrity (2023–2024), and, finally, to a designer and architect of AI-enhanced learning environments (2025). The study contributes to theory by extending the application of Dynamic Capabilities Theory to higher education governance and by demonstrating that teachers’ perceptions of AI serve as indicators of institutional resilience. Based on Dynamic Capabilities Theory, the managerial recommendations are divided into three levels: government, institutional, and scientific-didactic (academic). Full article
(This article belongs to the Special Issue Technology and Social Change in the Digital Age)
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23 pages, 3578 KB  
Article
Integrating Heritage, Mobility, and Sustainability: A TOD-Based Framework for Msheireb Downtown Doha
by Sarah Al-Thani, Jasim Azhar, Raffaello Furlan, Abdulla AlNuaimi, Hameda Janahi and Reem Awwaad
Heritage 2026, 9(1), 34; https://doi.org/10.3390/heritage9010034 (registering DOI) - 16 Jan 2026
Abstract
Transit-Oriented Development (TOD), formalized by Calthorpe and Poticha in 1993, emerged to counter urban sprawl, reduce car dependency, and revitalize historical community centers. Rooted in “new urbanism”, TOD emphasizes integrated regional land-use planning and high-capacity public transportation. In the Middle East, TOD implementation [...] Read more.
Transit-Oriented Development (TOD), formalized by Calthorpe and Poticha in 1993, emerged to counter urban sprawl, reduce car dependency, and revitalize historical community centers. Rooted in “new urbanism”, TOD emphasizes integrated regional land-use planning and high-capacity public transportation. In the Middle East, TOD implementation remains understudied, particularly regarding heritage integration and social equity in arid climates. Doha’s rapid social and economic transformation presents both opportunities and risks: growth offers urban revitalization yet threatens to displace communities and dilute cultural identity. Shifts in urban planning have aimed to address sustainability, connectivity, and heritage preservation. This study examines Msheireb Downtown Doha (MDD) to assess how TOD can restore historic districts while managing gentrification, enhancing accessibility and promoting inclusiveness. A mixed-methods approach was applied, including 12 semi-structured interviews with stakeholders (Qatar Rail, Msheireb Properties, Ministry of Municipality and Environment), purposive surveys of 80 urban users, site observations, and spatial mapping. Using the Node-Place-People (NPP) model, the study evaluates TOD effectiveness across transportation connectivity (node), built environment quality (place), and equity metrics (people). The findings show that MDD successfully implements fundamental TOD principles through its design, which enhances connectivity, walkability, social inclusiveness, and heritage preservation. However, multiple obstacles remain: the “peripheral island effect” limits benefits to the core, pedestrian–vehicular balance is unresolved, and commercial gentrification is on the rise. This research provides evidence-based knowledge for GCC cities pursuing sustainable urban regeneration by demonstrating both the advantages of TOD and the necessity for critical, context-sensitive implementation that focuses on social equity together with physical transformation. Full article
25 pages, 2024 KB  
Article
Nitrogen Dynamics and Environmental Sustainability in Rice–Crab Co-Culture System: Optimal Fertilization for Sustainable Productivity
by Hao Li, Shuxia Wu, Yang Xu, Weijing Li, Xiushuang Zhang, Siqi Ma, Wentao Sun, Bo Li, Bingqian Fan, Qiuliang Lei and Hongbin Liu
AgriEngineering 2026, 8(1), 34; https://doi.org/10.3390/agriengineering8010034 (registering DOI) - 16 Jan 2026
Abstract
Rice–crab co-culture systems (RC) represent promising sustainable intensification approaches, yet their nitrogen (N) cycling and optimal fertilization strategies remain poorly characterized. In this study, we compared RC with rice monoculture system (RM) across four N gradients (0, 150, 210, and 270 kg N·hm [...] Read more.
Rice–crab co-culture systems (RC) represent promising sustainable intensification approaches, yet their nitrogen (N) cycling and optimal fertilization strategies remain poorly characterized. In this study, we compared RC with rice monoculture system (RM) across four N gradients (0, 150, 210, and 270 kg N·hm−2), assessing N dynamics in field water and N distribution in soil. The results showed that field water ammonium nitrogen (NH4+-N) concentrations increased nonlinearly, showing sharp increases beyond 210 kg N·hm−2. Notably, crab activity in the RC altered the N transformation and transport processes, leading to a prolonged presence of nitrate nitrogen (NO3-N) in field water for two additional days after tillering fertilization compared to RM. This indicates a critical window for potential nitrogen loss risk, rather than enhanced retention, 15 days after basal fertilizer application. Compared to RM, RC exhibited enhanced nitrogen retention capacity, with NO3-N concentrations remaining elevated for an additional two days following tillering fertilization, suggesting a potential critical period for nitrogen loss risk. Post-harvest soil analysis revealed contrasting nitrogen distribution patterns: RC showed enhanced NH4+-N accumulation in surface layers (0–2 cm) with minimal vertical NO3-N redistribution, while RM exhibited progressive NO3-N increases in subsurface layers (2–10 cm) with increasing fertilizer rates. The 210 kg N·hm−2 rate proved optimal for the RC, producing a rice yield 12.08% higher than that of RM and sustaining high crab yields, while avoiding the excessive aqueous N levels seen at higher rates. It is important to note that these findings are based on a single-site, single-growing season field experiment conducted in Panjin, Liaoning Province, and thus the general applicability of the optimal nitrogen rate may require further validation across diverse environments. We conclude that a fertilization rate of 210 kg N·hm−2 is the optimal strategy for RC, effectively balancing productivity and environmental sustainability. This finding provides a clear, quantitative guideline for precise N management in integrated aquaculture systems. Full article
(This article belongs to the Section Sustainable Bioresource and Bioprocess Engineering)
27 pages, 804 KB  
Article
Sustainable Development Agenda: Historical Evolution, Goal Progression, and Future Prospects
by Chaofeng Shao, Sihan Chen and Xuesong Zhan
Sustainability 2026, 18(2), 948; https://doi.org/10.3390/su18020948 (registering DOI) - 16 Jan 2026
Abstract
The concept of sustainable development has emerged as a global consensus, forged in response to environmental constraints and critical reflection on conventional growth-oriented paradigms. It now serves as the overarching framework for addressing climate, ecological, and socio-economic crises. In the period after the [...] Read more.
The concept of sustainable development has emerged as a global consensus, forged in response to environmental constraints and critical reflection on conventional growth-oriented paradigms. It now serves as the overarching framework for addressing climate, ecological, and socio-economic crises. In the period after the adoption of the Sustainable Development Goals (SDGs) in 2016, there was an observable trend of increased integration of these objectives into the strategic frameworks of national and subnational entities. However, global assessments have indicated a divergence between the progress achieved and the trajectory delineated by the SDGs. The Earth system is demonstrating signs of decreased resilience, with widening inequalities and the emergence of multiple crises, thereby hindering the implementation of the 2030 Agenda for Sustainable Development. As the 2030 deadline approaches, a fundamental question arises for global development governance: what should be the future of the SDGs beyond 2030? While insufficient progress has prompted debates over the adequacy of the SDG framework, fundamentally revising or replacing the SDGs would risk undermining a hard-won international consensus forged through decades of negotiation and institutional investment. Based on a comprehensive review of the historical evolution of the sustainable development concept, this study argues that the SDGs represent a rare and fragile achievement in global governance. While insufficient progress has sparked debates about their effectiveness, fundamentally revising or replacing the SDGs would jeopardize the hard-won international consensus forged through decades of negotiations and institutional investments. This study further analyzes the latest progress on the SDGs and identifies emerging risks, aiming to explore how to accelerate and optimize sustainable development pathways within the existing SDG framework rather than propose a new global goal system. Based on both global experience and practice in China, four interconnected strategic priorities—namely, economic reform, social equity, environmental justice, and technology sharing—are proposed as a comprehensive framework to accelerate SDG implementation and guide the transformation of development pathways towards a more just, low-carbon, and resilient future. Full article
21 pages, 705 KB  
Article
Rethinking Career Sustainability Through the Lens of AI Affordance: The Exploratory Role of Knowledge Sharing
by Muhammad Waleed Ayub Ghouri, Tachia Chin and Muhammad Ali Hussain
Sustainability 2026, 18(2), 941; https://doi.org/10.3390/su18020941 - 16 Jan 2026
Abstract
Artificial intelligence (AI), a transformative force, has revolutionised various aspects of human life and business operations. This has led to a drastic mutation of the career landscape, embedded with vast opportunities as well as challenges, particularly concerning career sustainability (CS). Despite myriad studies [...] Read more.
Artificial intelligence (AI), a transformative force, has revolutionised various aspects of human life and business operations. This has led to a drastic mutation of the career landscape, embedded with vast opportunities as well as challenges, particularly concerning career sustainability (CS). Despite myriad studies on CS, the paradoxical interplay of AI and CS remains underexplored, particularly for expatriates (expats). To address the aforementioned gap, our study incorporates an affordance perspective (AFP), positioning AI as an object and CS as a user context. Specifically, this study investigates whether AI facilitates the orchestration of an enhanced sustainable career within the boundary conditions of knowledge sharing (KS), encompassing both tacit and explicit knowledge pertinent to AI, cultivated through managerial initiatives and employee-driven activities. The study conducted a quantitative survey among 490 expats working in AI-integrated environments in China. The results reveal a curvilinear (U-shaped) relationship between AI and CS, where AI affordance at a moderate level enhances career adaptability and skill development. However, digital affordances become complex beyond a certain threshold, creating several career concerns, such as job insecurity and role ambiguity. Furthermore, the moderating effect of tacit and explicit KS mitigates numerous career disruptions while fostering long-term career growth. The study framed AI as both a tool and a collaborator that illuminates the importance of AI–human intelligence (AI–HI) synergy and knowledge augmentation in navigating digital transitions. Moreover, implications for international career development and human-oriented digital transformation are also discussed. Full article
20 pages, 1359 KB  
Article
Optimization of the Extraction Process for Anthocyanins from Tannat Grape Skins and Pomace and Research on Their Antioxidant and Anti-Aging Effects
by Bing Wang, Yang Yu and Honglei Wang
Agriculture 2026, 16(2), 236; https://doi.org/10.3390/agriculture16020236 - 16 Jan 2026
Abstract
Grape pomace is a major byproduct of winemaking and a rich source of bioactive anthocyanins with potential functional value. This study aimed to optimize anthocyanin extraction from Tannat grape pomace and evaluate its antioxidant and anti-aging activities. Ultrasonic-assisted extraction combined with a Box–Behnken [...] Read more.
Grape pomace is a major byproduct of winemaking and a rich source of bioactive anthocyanins with potential functional value. This study aimed to optimize anthocyanin extraction from Tannat grape pomace and evaluate its antioxidant and anti-aging activities. Ultrasonic-assisted extraction combined with a Box–Behnken design identified optimal conditions of 51.27 °C, 53.46% ethanol, 20.10 min ultrasonication, and a 1:24.05 solid-to-liquid ratio, yielding 186.21 ± 1.03 mg/100 g (R2 = 0.9798, p < 0.0001). Tannat Grape Pomace Anthocyanins showed strong antioxidant capacity, with 2,2-Diphenyl-1-picrylhydrazyl scavenging of 89.44% ± 0.87% at 0.2 mg/mL (IC50 = 0.09 mg/mL) and 2,2′-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) scavenging of 95.83% ± 0.54% at 0.75 mg/mL (IC50 = 0.26 mg/mL). In Caenorhabditis elegans, TGPA extended lifespan, improved motility, and increased heat and oxidative stress resistance without reducing reproductive capacity. Lifespan is a key indicator of aging. This study holds significant implications for advancing our understanding of the mechanisms underlying lifespan regulation, the connection between aging and disease, as well as the development of anti-aging therapies for humans. In conclusion, these findings indicate that Tannat Grape Pomace Anthocyanins possess promising antioxidant and anti-aging potential and support the sustainable, high-value utilization of grape pomace. This approach directly aligns with the core principles of sustainable agriculture by transforming an agricultural byproduct into a valuable resource. Full article
(This article belongs to the Section Agricultural Technology)
28 pages, 11292 KB  
Article
Between Nature and City: Translating Nature’s Inspiration into Ecosystem Services Solutions for Hot Climate Resilience
by Ruaa M. Ismail, Merhan M. Shahda, Sara Eltarabily and Naglaa A. Megahed
Sustainability 2026, 18(2), 935; https://doi.org/10.3390/su18020935 - 16 Jan 2026
Abstract
The increasing challenges of urbanization and environmental degradation have led to a greater need for built environments that minimize ecological consequences while actively contributing to ecosystem services (ES). Bio-Inspired Design (BID) is a promising approach that translates natural-system ideas into architectural and urban [...] Read more.
The increasing challenges of urbanization and environmental degradation have led to a greater need for built environments that minimize ecological consequences while actively contributing to ecosystem services (ES). Bio-Inspired Design (BID) is a promising approach that translates natural-system ideas into architectural and urban solutions. This study investigates how BID can be used to deliver and improve ecosystem services, like climate regulation, air purification, and energy, in the built environment, focusing on applications in hot climates and at the meso scale. The study conducts a qualitative and integrative analysis of bio-inspired concepts derived from existing research and innovative practices. It examines specific ecosystem services—selected based on previous studies—and illustrates how these strategies can improve environmental performance in urban contexts. A conceptual framework for linking biological analogies to urban functions is proposed. The framework emphasizes the interdisciplinary relationships between architecture, urban design, material science, and environmental engineering. This provides a helpful guide for researchers and practitioners on how to use BID to enhance sustainability results. The study suggests that incorporating BID principles into urban design procedures can potentially transform built environments into active contributors to ecosystem functioning, enabling them to provide ES rather than merely consuming resources. While this conclusion is conceptual, the framework highlights pathways for more resilient and sustainable urban futures. Full article
(This article belongs to the Section Green Building)
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22 pages, 5927 KB  
Article
Research on a Temperature and Humidity Prediction Model for Greenhouse Tomato Based on iT-LSTM-CA
by Yanan Gao, Pingzeng Liu, Yuxuan Zhang, Fengyu Li, Ke Zhu, Yan Zhang and Shiwei Xu
Sustainability 2026, 18(2), 930; https://doi.org/10.3390/su18020930 - 16 Jan 2026
Abstract
Constructing a temperature and humidity prediction model for greenhouse-grown tomatoes is of great significance for achieving resource-efficient and sustainable greenhouse environmental control and promoting healthy tomato growth. However, traditional models often struggle to simultaneously capture long-term temporal trends, short-term local dynamic variations, and [...] Read more.
Constructing a temperature and humidity prediction model for greenhouse-grown tomatoes is of great significance for achieving resource-efficient and sustainable greenhouse environmental control and promoting healthy tomato growth. However, traditional models often struggle to simultaneously capture long-term temporal trends, short-term local dynamic variations, and the coupling relationships among multiple variables. To address these issues, this study develops an iT-LSTM-CA multi-step prediction model, in which the inverted Transformer (iTransformer, iT) is employed to capture global dependencies across variables and long temporal scales, the Long Short-Term Memory (LSTM) network is utilized to extract short-term local variation patterns, and a cross-attention (CA) mechanism is introduced to dynamically fuse the two types of features. Experimental results show that, compared with models such as Gated Recurrent Unit (GRU), Temporal Convolutional Network (TCN), Recurrent Neural Network (RNN), LSTM, and Bidirectional Long Short-Term Memory (Bi-LSTM), the iT-LSTM-CA achieves the best performance in multi-step forecasting tasks at 3 h, 6 h, 12 h, and 24 h horizons. For temperature prediction, the R2 ranges from 0.96 to 0.98, with MAE between 0.42 °C and 0.79 °C and RMSE between 0.58 °C and 1.06 °C; for humidity prediction, the R2 ranges from 0.95 to 0.97, with MAE between 1.21% and 2.49% and RMSE between 1.78% and 3.42%. These results indicate that the iT-LSTM-CA model can effectively capture greenhouse environmental variations and provide a scientific basis for environmental control and management in tomato greenhouses. Full article
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42 pages, 907 KB  
Article
Digital Transformation and Sustainable Customer Value in Healthcare: Evidence from an AI-Based Diabetes Prognostic Service
by Oh Suk Yang and Seong Hun Kim
Sustainability 2026, 18(2), 928; https://doi.org/10.3390/su18020928 - 16 Jan 2026
Abstract
This study investigates how digital transformation in healthcare shapes sustainable customer value by analyzing the role of digital quality and its influence on satisfaction and loyalty within an AI-based diabetes prognostic service. Drawing on system, information, and service quality as core dimensions of [...] Read more.
This study investigates how digital transformation in healthcare shapes sustainable customer value by analyzing the role of digital quality and its influence on satisfaction and loyalty within an AI-based diabetes prognostic service. Drawing on system, information, and service quality as core dimensions of digital quality, the study examines their direct effects on satisfaction and their contribution to loyalty formation relative to traditional service factors. Using survey data collected from over 1000 users of a digital healthcare platform equipped with an AI-driven diabetes prognostic algorithm, 800 valid responses were analyzed through PLS-SEM in SmartPLS 4.0. The results show that both traditional service attributes and digital quality significantly enhance customer satisfaction, which in turn promotes loyalty. However, digital quality does not strengthen the satisfaction–loyalty linkage, indicating that its value lies in establishing baseline trust and usability rather than amplifying loyalty outcomes. Environmental uncertainty—captured as technological and market uncertainty—also positively affects loyalty. This study contributes to digital healthcare research by providing empirical evidence from an AI-based long-term prognostic service and clarifying that digital quality operates as a foundational hygiene factor essential for sustainable customer value, rather than as a competitive differentiator. Full article
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33 pages, 4974 KB  
Article
AI-Enabled Sustainable Landscape Design: A Decision-Support Framework Based on “Generative-Critical” Multi-Agent
by Li Li, Xuesong Yang, Sijia Liu and Feiyang Deng
Urban Sci. 2026, 10(1), 56; https://doi.org/10.3390/urbansci10010056 - 16 Jan 2026
Abstract
Under the dual pressures of global climate change and accelerating urbanization, landscape design has been tasked with the critical mission of enhancing urban environmental resilience and ecological livability. However, conventional design practices often struggle to efficiently integrate complex sustainability norms with aesthetic creativity, [...] Read more.
Under the dual pressures of global climate change and accelerating urbanization, landscape design has been tasked with the critical mission of enhancing urban environmental resilience and ecological livability. However, conventional design practices often struggle to efficiently integrate complex sustainability norms with aesthetic creativity, leading to a disconnect between form and function. To address this issue, this study proposes and validates an AI-enabled sustainability decision-support framework. The framework is based on a “Generative-Critical” multi-agent workflow that enables “Self-Correcting” iterative optimization of design schemes through a built-in expert knowledge base and a quantitative scorecard. The framework’s effectiveness was validated through a cultural park case study and a blind evaluation by 10 experts. It guided a design from an initial concept with only aesthetic forms and lacking effective stormwater management, to an ecologically integrated scheme that strategically incorporated bioretention ponds at key nodes and converted hard plazas into permeable pavements. This transformation significantly elevated the scheme’s sustainability score from 59.3 to 88.0 (p < 0.001), while the framework itself achieved a high system usability scale (SUS) score of 85.5. These results confirm that the proposed “Generative-Critical” mechanism can effectively guide AIGC to adhere to ecological-technical norms and constraints while pursuing aesthetic innovation, thereby achieving a scientific integration of aesthetic form and ecological function at the early conceptual design stage. This study offers a scalable methodology for AI-assisted sustainable design and provides a novel intelligent tool for creating resilient urban landscapes that possess both environmental performance and aesthetic value. Full article
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32 pages, 3412 KB  
Review
Engineering Immunity: Current Progress and Future Directions of CAR-T Cell Therapy
by Mouldy Sioud and Nicholas Paul Casey
Int. J. Mol. Sci. 2026, 27(2), 909; https://doi.org/10.3390/ijms27020909 - 16 Jan 2026
Abstract
Chimeric antigen receptor (CAR)-T cell therapy has emerged as a transformative form of immunotherapy, enabling the precise engineering of T cells to recognize and eliminate pathogenic cells. In hematologic malignancies, CAR-T cells targeting CD19 or B cell maturation antigens have achieved remarkable remission [...] Read more.
Chimeric antigen receptor (CAR)-T cell therapy has emerged as a transformative form of immunotherapy, enabling the precise engineering of T cells to recognize and eliminate pathogenic cells. In hematologic malignancies, CAR-T cells targeting CD19 or B cell maturation antigens have achieved remarkable remission rates and durable responses in patients with otherwise refractory disease. Despite these successes, extending CAR-T cell therapy to solid tumors remains challenging due to antigen heterogeneity, poor T cell infiltration, and the immunosuppressive tumor microenvironment (TME). Beyond oncology, CAR-T cell therapy has also shown promise in autoimmune diseases, where early clinical studies suggest that B cell-directed CAR-T cells can induce sustained remission in conditions such as systemic lupus erythematosus. This review highlights advances in CAR-T cell engineering, including DNA- and mRNA-based platforms for ex vivo and in vivo programming, and discusses emerging strategies to enhance CAR-T cell trafficking, persistence, and resistance to TME. Full article
(This article belongs to the Special Issue Molecular Mechanisms of Immunotherapy in Cancer)
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31 pages, 9338 KB  
Review
Biotechnological Strategies to Enhance Maize Resilience Under Climate Change
by Kyung-Hee Kim, Donghwa Park and Byung-Moo Lee
Biology 2026, 15(2), 161; https://doi.org/10.3390/biology15020161 - 16 Jan 2026
Abstract
Maize (Zea mays L.), a vital crop for global food and economic security, faces intensifying biotic and abiotic stresses driven by climate change, including drought, heat, and erratic rainfall. This review synthesizes emerging biotechnology-driven strategies designed to enhance maize resilience under these [...] Read more.
Maize (Zea mays L.), a vital crop for global food and economic security, faces intensifying biotic and abiotic stresses driven by climate change, including drought, heat, and erratic rainfall. This review synthesizes emerging biotechnology-driven strategies designed to enhance maize resilience under these shifting environmental conditions. We present an integrated framework that encompasses CRISPR/Cas9 and next-generation genome editing, Genomic Selection (GS), Environmental Genomic Selection (EGS), and multi-omics platforms—spanning transcriptomics, proteomics, metabolomics, and epigenomics. These approaches have significantly deepened our understanding of complex stress-adaptive traits and genotype-by-environment interactions, revealing precise targets for breeding climate-resilient cultivars. Furthermore, we highlight enabling technologies such as high-throughput phenotyping, artificial intelligence (AI), and nanoparticle-based gene delivery—including novel in planta and transformation-free protocols—that are accelerating translational breeding. Despite these technical breakthroughs, barriers such as genotype-dependent transformation efficiency, regulatory landscapes, and implementation costs in resource-limited settings remain. Bridging the gap between laboratory innovation and field deployment will require coordinated policy support and global collaboration. By integrating molecular breakthroughs with practical deployment strategies, this review offers a comprehensive roadmap for developing sustainable, climate-resilient maize varieties to meet future agricultural demands. Full article
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