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Article

5 Citations

2,272 Views

16 Pages

Surrogate Virus Neutralisation Test Based on Nanoluciferase-Tagged Antigens to Quantify Inhibitory Antibodies against SARS-CoV-2 and Characterise Omicron-Specific Reactivity in a Vaccination Cohort

Michael Schoefbaenker,
Rieke Neddermeyer,
Theresa Guenther,
Marlin M. Mueller,
Marie-Luise Romberg,
Nica Classen,
Marc T. Hennies,
Eike R. Hrincius,
Stephan Ludwig and
Eva U. Lorentzen
+ 1 author

Vaccines2023, 11(12), 1832;https://doi.org/10.3390/vaccines11121832

8 December 2023

Virus-specific antibodies are crucial for protective immunity against SARS-CoV-2. Assessing functional antibodies through conventional or pseudotyped virus neutralisation tests (pVNT) requires high biosafety levels. Alternatively, the virus-free surr...

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Article

6 Citations

4,160 Views

11 Pages

Evaluation of a Pseudotyped Virus Neutralisation Test for the Measurement of Equine Influenza Virus-Neutralising Antibody Responses Induced by Vaccination and Infection

Rebecca Kinsley,
Stéphane Pronost,
Manuelle De Bock,
Nigel Temperton,
Janet M. Daly,
Romain Paillot and
Simon Scott

Vaccines2020, 8(3), 466;https://doi.org/10.3390/vaccines8030466

21 August 2020

Equine influenza is a major respiratory disease of horses that is largely controlled by vaccination in some equine populations. Virus-neutralising antibodies, the mainstay of the protective immune response, are problematic in assaying for equine infl...

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Article

3 Citations

2,445 Views

11 Pages

SARS-CoV-2 Surveillance between 2020 and 2021 of All Mammalian Species in Two Flemish Zoos (Antwerp Zoo and Planckendael Zoo)

Léa Joffrin,
Tine Cooreman,
Erik Verheyen,
Francis Vercammen,
Joachim Mariën,
Herwig Leirs and
Sophie Gryseels

Vet. Sci.2023, 10(6), 382;https://doi.org/10.3390/vetsci10060382

31 May 2023

The COVID-19 pandemic has led to millions of human infections and deaths worldwide. Several other mammal species are also susceptible to SARS-CoV-2, and multiple instances of transmission from humans to pets, farmed mink, wildlife and zoo animals hav...

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Communication

12 Citations

2,975 Views

9 Pages

Dynamics of Neutralizing Antibody Responses Following Natural SARS-CoV-2 Infection and Correlation with Commercial Serologic Tests. A Reappraisal and Indirect Comparison with Vaccinated Subjects

Constant Gillot,
Julien Favresse,
Vincent Maloteau,
Jean-Michel Dogné and
Jonathan Douxfils

Viruses2021, 13(11), 2329;https://doi.org/10.3390/v13112329

22 November 2021

Neutralising antibodies (NAbs) represent the real source of protection against SARS-CoV-2 infections by preventing the virus from entering target cells. The gold standard in the detection of these antibodies is the plaque reduction neutralization tes...

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