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153 Results Found

  • Article
  • Open Access
31 Citations
9,227 Views
6 Pages

Surface Plasmon Resonance Studies on Molecular Imprinting

  • Ping Li,
  • Yan Huang,
  • Junze Hu,
  • Chunwei Yuan and
  • Baoping Lin

19 January 2002

The molecular imprinted polymer (MIP) members were fabricated with the print molecule L-phenylalanine ethyl ester. The elution and adsorption procedures were investigated by surface plasmon resonance in situ. The changes of refractive angle during el...

  • Feature Paper
  • Review
  • Open Access
110 Citations
21,096 Views
33 Pages

Surface Plasmon Resonance-Based Fiber Optic Sensors Utilizing Molecular Imprinting

  • Banshi D. Gupta,
  • Anand M. Shrivastav and
  • Sruthi P. Usha

29 August 2016

Molecular imprinting is earning worldwide attention from researchers in the field of sensing and diagnostic applications, due to its properties of inevitable specific affinity for the template molecule. The fabrication of complementary template impri...

  • Article
  • Open Access
19 Citations
5,606 Views
16 Pages

9 March 2018

Molecularly imprinted polymer (MIP) films prepared by bulk polymerization suffer from numerous deficiencies, including poor mass transfer ability and difficulty in controlling reaction rate and film thickness, which usually result in poor repeatabili...

  • Article
  • Open Access
21 Citations
6,999 Views
11 Pages

Combined Layer/Particle Approaches in Surface Molecular Imprinting of Proteins: Signal Enhancement and Competition

  • Nam Van Ho Phan,
  • Hermann F. Sussitz,
  • Eva Ladenhauf,
  • Dietmar Pum and
  • Peter A. Lieberzeit

10 January 2018

Herein we report novel approaches to the molecular imprinting of proteins utilizing templates sizing around 10 nm and some 100 nm. The first step comprised synthesizing nanoparticles of molecularly imprinted polymers (MIP) towards bovine serum albumi...

  • Review
  • Open Access
268 Citations
15,525 Views
17 Pages

4 February 2017

Molecular imprinting is the technology of creating artificial recognition sites in polymeric matrices which are complementary to the template in their size, shape and spatial arrangement of the functional groups. Molecularly imprinted polymers (MIPs)...

  • Article
  • Open Access
33 Citations
4,669 Views
14 Pages

15 January 2021

In this study, we designed a simple, rapid, sensitive and selective surface plasmon resonance (SPR) sensor for detection of L-phenylalaine by utilizing molecular imprinting technology. l-phenylalanine imprinted and non-imprinted poly(2-hydroxyethyl m...

  • Article
  • Open Access
19 Citations
4,902 Views
17 Pages

10 September 2018

A highly sensitive and selective Raman sensor has been developed by combining molecularly imprinted cavities, silver nanoparticles, and graphene oxide into a hybrid organic-inorganic film. The molecular imprinted nanocomposite material is an advanced...

  • Article
  • Open Access
16 Citations
6,819 Views
10 Pages

23 July 2015

Self-assembly and molecular imprinting technologies are very attractive technologies for the development of artificial recognition systems and provide chemical recognition based on need and not happenstance. In this paper, we employed a b-cyclodextr...

  • Article
  • Open Access
45 Citations
8,670 Views
15 Pages

A Facile Approach for Fabrication of Core-Shell Magnetic Molecularly Imprinted Nanospheres towards Hypericin

  • Wenxia Cheng,
  • Fengfeng Fan,
  • Ying Zhang,
  • Zhichao Pei,
  • Wenji Wang and
  • Yuxin Pei

7 April 2017

By taking advantage of the self-polymerization of dopamine on the surface of magnetic nanospheres in weak alkaline Tris-HCl buffer solution, a facile approach was established to fabricate core-shell magnetic molecularly imprinted nanospheres towards...

  • Article
  • Open Access
45 Citations
5,876 Views
16 Pages

11 May 2018

The influence of various silica gel supports with different shapes and sizes on the recognition properties of surface molecular imprinted polymers (MIPs) was investigated. MIPs for selective recognition and adsorption of gossypol were synthesized via...

  • Article
  • Open Access
46 Citations
8,442 Views
11 Pages

5 September 2011

The aim of the present work was to investigate the feasibility of applying the molecular imprinting polymer technique to the detection of the mycotoxin deoxynivalenol (DON) using a surface plasmon resonance (SPR) transducer. A molecularly imprinted p...

  • Article
  • Open Access
28 Citations
6,478 Views
18 Pages

COVID-19 caused by a SARS-CoV-2 infection was first reported from Wuhan, China, and later recognized as a pandemic on March 11, 2020, by the World Health Organization (WHO). Gold standard nucleic acid and molecular-based testing have largely satisfie...

  • Feature Paper
  • Article
  • Open Access
59 Citations
5,696 Views
13 Pages

9 September 2018

Hemoglobin is an iron carrying protein in erythrocytes and also an essential element to transfer oxygen from the lungs to the tissues. Abnormalities in hemoglobin concentration are closely correlated with health status and many diseases, including th...

  • Article
  • Open Access
5 Citations
2,579 Views
14 Pages

25 March 2023

In this study, Zn(NO3)2·6H2O was selected as the metal source, and ZIF-7-modified magnetic graphene-based matrix materials (MRGO@ZIF-7) were prepared by in situ growth. ZIF-7 modified magnetic graphene-based molecular imprinting complexes (MRG...

  • Article
  • Open Access
8 Citations
2,610 Views
16 Pages

Simple and Fast Pesticide Nanosensors: Example of Surface Plasmon Resonance Coumaphos Nanosensor

  • Beste Oymen,
  • Mitra Jalilzadeh,
  • Fatma Yılmaz,
  • Süleyman Aşır,
  • Deniz Türkmen and
  • Adil Denizli

23 March 2023

Here, a molecular imprinting technique was employed to create an SPR-based nanosensor for the selective and sensitive detection of organophosphate-based coumaphos, a toxic insecticide/veterinary drug often used. To achieve this, UV polymerization was...

  • Article
  • Open Access
193 Citations
17,563 Views
15 Pages

1 March 2011

We report on a new sensor strategy that integrates molecularly imprinted polymers (MIPs) with surface enhanced Raman scattering (SERS). The sensor was developed to detect the explosive, 2,4,6-trinitrotoluene (TNT). Micron thick films of sol gel-deriv...

  • Communication
  • Open Access
23 Citations
2,672 Views
12 Pages

Thiram Determination in Milk Samples by Surface Plasmon Resonance Based on Molecularly Imprinted Polymers and Sulphur-Doped Titanium Dioxide

  • Sezen Harmankaya,
  • Hacı Ahmet Deveci,
  • Ahmet Harmankaya,
  • Fatma Hazan Gül,
  • Necip Atar and
  • Mehmet Lütfi Yola

3 July 2024

In this work, a new surface plasmon resonance (SPR) sensor based on sulphur-doped titanium dioxide (S-TiO2) nanostructures and molecularly imprinted polymer (MIP) was presented for thiram (THI) determination in milk samples. Firstly, the S-TiO2 nanom...

  • Article
  • Open Access
1 Citations
1,797 Views
13 Pages

Molecularly Imprinted SERS Plasmonic Sensor for the Detection of Malachite Green

  • Hao Zhang,
  • Dani Sun,
  • Yuhao Wen,
  • Mengyuan Wang,
  • Jingying Huang,
  • Ziru Lian and
  • Jinhua Li

20 May 2025

Malachite green (MG) is a highly toxic dye commonly used in industries and aquaculture, leading to significant environmental contamination and health hazards. Therefore, sensitive and selective detection of MG in real samples is urgently needed. This...

  • Article
  • Open Access
3 Citations
1,147 Views
15 Pages

31 December 2024

Chrysoidin (CG) can be ingested into the human body through the skin and cause chronic toxicity, so the detection of CG levels in the environment is crucial. In this study, we synthesize F-Ag@ZIF-8/PVC molecular-imprinted membranes (FZAP-MIM) by an i...

  • Article
  • Open Access
1 Citations
1,541 Views
13 Pages

Biomimetic Prussian Blue Sensor for Ultrasensitive Direct Detection of Myoglobin

  • Jacinta Ricardo,
  • Abel Duarte,
  • Stefano Chiussi,
  • Gabriela V. Martins and
  • Felismina T. C. Moreira

26 February 2025

This research presents a novel, cost-effective, and scalable approach for the direct detection of myoglobin (Myo) in point-of-care (PoC) applications. In this strategy, redox-active Prussian Blue nanocubes (PBNCs) are applied to a disposable platinum...

  • Article
  • Open Access
19 Citations
5,162 Views
13 Pages

13 February 2019

The core-shell structure molecularly imprinted magnetic nanospheres towards hypericin (Fe3O4@MIPs) were prepared by mercapto-alkyne click polymerization. The shape and size of nanospheres were characterized by dynamic light scattering (DLS) and trans...

  • Article
  • Open Access
147 Views
12 Pages

Trace Detection of Ibuprofen in Solution Based on Surface Plasmon Resonance Technology

  • Sijia Han,
  • Zhitao Yang,
  • Songlin Jia,
  • Fenglei Zhao and
  • Zehong Xu

4 January 2026

A surface plasmon resonance (SPR) sensor utilizing a molecularly imprinted polymer (MIP) film as the recognition element was developed for the selective detection of the non-steroidal anti-inflammatory drug ibuprofen (IBU). The molecularly imprinted...

  • Article
  • Open Access
25 Citations
8,846 Views
13 Pages

Surface Molecularly Imprinted Polymer Film with Poly(p-aminothiophenol) Outer Layer Coated on Gold Nanoparticles Inner Layer for Highly Sensitive and Selective Sensing Paraoxon

  • Shanshan Li,
  • Qingying Luo,
  • Yaowen Liu,
  • Zhiqing Zhang,
  • Guanghui Shen,
  • Hejun Wu,
  • Anjun Chen,
  • Xingyan Liu and
  • Aidong Zhang

12 August 2017

This paper presents the fabrication of a molecularly imprinted, polymer-based disposable electrochemical sensor for paraoxon (PO) determination. The sensor was based on a screen-printed carbon electrode (SPCE) modified with a surface molecularly impr...

  • Article
  • Open Access
11 Citations
3,454 Views
15 Pages

29 August 2022

Combining molecular imprinted polymers and water-soluble manganese-doped zinc sulfide quantum dots (Mn2+: ZnS QDs), a new molecule imprinted polymers-based fluorescence sensor was designed. The molecule imprinted quantum dots (MIP@QDs) were construct...

  • Communication
  • Open Access
29 Citations
8,521 Views
11 Pages

26 September 2013

A fluorescent molecularly imprinted nanosensor was obtained by grafting imprinted polymer onto the surface of multi-wall carbon nanotubes and post-imprinting treatment with fluorescein isothiocyanate (FITC). The fluorescence of lysozyme-imprinted pol...

  • Feature Paper
  • Review
  • Open Access
266 Citations
23,217 Views
19 Pages

Molecularly Imprinted Polymer Based Sensors for Medical Applications

  • Yeşeren Saylan,
  • Semra Akgönüllü,
  • Handan Yavuz,
  • Serhat Ünal and
  • Adil Denizli

13 March 2019

Sensors have been extensively used owing to multiple advantages, including exceptional sensing performance, user-friendly operation, fast response, high sensitivity and specificity, portability, and real-time analysis. In recent years, efforts in sen...

  • Article
  • Open Access
19 Citations
7,029 Views
17 Pages

6 August 2017

Malachite green (MG) is currently posing a carcinogenic threat to the safety of human lives; therefore, it is highly desirable to develop an effective method for fast trace detection of MG. Herein, for the first time, this paper presents a systematic...

  • Article
  • Open Access
1,354 Views
13 Pages

27 September 2024

Development in hemoglobin-based oxygen carriers (HBOCs) that may be used as alternatives to donated blood requires an extensive supply of highly pure hemoglobin (Hb) preparations. Therefore, it is essential to fabricate inexpensive, stable and highly...

  • Article
  • Open Access
8 Citations
1,905 Views
13 Pages

14 March 2024

Molecular imprinting technology is widely used for the specific identification of compounds, but the selective recognition mechanisms of the same compounds still need to be further studied. Based on differences in hydrogen bond size and orientation,...

  • Article
  • Open Access
17 Citations
9,691 Views
12 Pages

Chemical Sensors – from Molecules, Complex Mixtures to Cells – Supramolecular Imprinting Strategies

  • Franz L. Dickert,
  • Peter A. Lieberzeit,
  • Oliver Hayden,
  • Sylvia Gazda-Miarecka,
  • Konstantin Halikias,
  • Karl Jürgen Mann and
  • Christian Palfinger

11 September 2003

Methods of modern chemistry are a powerful tool in generating functional materials suitable as chemically sensitive layers to be combined with a variety of transducer principles. Molecular pits in polymers are formed by molecular imprinting, by suita...

  • Article
  • Open Access
6 Citations
1,859 Views
13 Pages

Investigations of Micro-Deformation in Monocrystalline Copper at Low Temperatures via Indentation

  • Shunbo Wang,
  • Dan Zhao,
  • Yihan Niu,
  • Zhaoxin Wang,
  • Hongxiu Yang and
  • Hongwei Zhao

30 June 2022

Indentation experiments on differently oriented faces of monocrystalline copper were conducted to investigate the micro-deformation process at temperatures ranging from room temperature to 150 K. The morphologies and textures of the residual imprints...

  • Article
  • Open Access
4 Citations
2,157 Views
11 Pages

Selective Detection of Erythrocytes with QCMs—ABO Blood Group Typing

  • Usman Latif,
  • Alexandra Seifner and
  • Franz L. Dickert

30 August 2023

Blood transfusion, as well as organ transplantation, is only possible after prior blood group (BG) typing and crossmatching. The most important blood group system is that of Landsteiner’s ABO classification based on antigen presence on the eryt...

  • Article
  • Open Access
42 Citations
10,091 Views
13 Pages

Molecularly Imprinted Quartz Crystal Microbalance Sensor (QCM) for Bilirubin Detection

  • Çiğdem Çiçek,
  • Fatma Yılmaz,
  • Erdoğan Özgür,
  • Handan Yavuz and
  • Adil Denizli

This study aims the preparation of a QCM sensor for the detection of bilirubin in human plasma. Bilirubin-imprinted poly-(2-hydroxyethyl methacrylate-N-methacryloyl-l-tryptophan methyl ester) (PHEMATrp) nanofilm (MIP) on the gold surface of a QCM chi...

  • Article
  • Open Access
84 Citations
9,361 Views
12 Pages

5 February 2015

Response of highly sensitive SnO2 semiconductor carbon monoxide (CO) gas sensors based on target gas CO quasi-molecular-imprinting mechanism design is investigated with gas concentrations varied from 50 to 3000 ppm. SnO2 nanoparticles prepared via hy...

  • Review
  • Open Access
166 Citations
12,368 Views
23 Pages

16 September 2021

Molecular imprinting is a technique for creating artificial recognition sites on polymer matrices that complement the template in terms of size, shape, and spatial arrangement of functional groups. The main advantage of Molecularly Imprinted Polymers...

  • Article
  • Open Access
12 Citations
3,817 Views
9 Pages

15 February 2018

Molecularly imprinted thin layers were prepared in silica capillaries by using two different surface polymerization strategies, the first using 4,4′-azobis(4-cyanovaleric acid) as a surface-coupled radical initiator, and the second, S-carboxypropyl-...

  • Article
  • Open Access
8 Citations
2,191 Views
13 Pages

In this study, β-Bi2O3 nanosheets functionalized with bisphenol A (BPA) synthetic receptors were developed by a simple molecular imprinting technology and applied as the photoelectric active material for the construction of a BPA photoelectroche...

  • Review
  • Open Access
16 Citations
3,457 Views
35 Pages

Porogenic Solvents in Molecularly Imprinted Polymer Synthesis: A Comprehensive Review of Current Practices and Emerging Trends

  • Gil van Wissen,
  • Joseph W. Lowdon,
  • Thomas J. Cleij,
  • Kasper Eersels and
  • Bart van Grinsven

14 April 2025

The versatility of molecularly imprinted polymers (MIPs) has led to their integration into applications like biosensing, separation, environmental monitoring, and drug delivery technologies. This diversity of applications has resulted in a plethora o...

  • Article
  • Open Access
5 Citations
3,298 Views
15 Pages

Controllable Fabrication of Molecularly Imprinted Microspheres with Nanoporous and Multilayered Structure for Dialysate Regeneration

  • Hongchi Wu,
  • Shanguo Zhang,
  • Lu Liu,
  • Yukun Ren,
  • Chun Xue,
  • Wenlong Wu,
  • Xiaoming Chen and
  • Hongyuan Jiang

27 January 2022

Adsorption of urea from dialysate is essential for wearable artificial kidneys (WRK). Molecularly imprinted microspheres with nanoporous and multilayered structures are prepared based on liquid–liquid phase separation (LLPS), which can selectiv...

  • Article
  • Open Access
35 Citations
6,387 Views
14 Pages

Molecularly Imprinted Composite Membranes for Selective Detection of 2-Deoxyadenosine in Urine Samples

  • Sonia Scorrano,
  • Lucia Mergola,
  • Maria Pia Di Bello,
  • Maria Rosaria Lazzoi,
  • Giuseppe Vasapollo and
  • Roberta Del Sole

16 June 2015

An important challenge for scientific research is the production of artificial systems able to mimic the recognition mechanisms occurring at the molecular level in living systems. A valid contribution in this direction resulted from the development o...

  • Article
  • Open Access
9 Citations
3,506 Views
13 Pages

Towards Molecularly Imprinted Polypyrrole-Based Sensor for the Detection of Methylene Blue

  • Raimonda Boguzaite,
  • Greta Pilvenyte,
  • Vilma Ratautaite,
  • Ernestas Brazys,
  • Almira Ramanaviciene and
  • Arunas Ramanavicius

This study is dedicated to molecularly imprinted polymer-based sensor development for methylene blue detection. The sensor was designed by molecular imprinting of polypyrrole with phenothiazine derivative methylene blue (MB) as a template molecule. T...

  • Feature Paper
  • Article
  • Open Access
305 Views
17 Pages

Electrochemical Detection of Levofloxacin Using a Polydopamine-Based Molecular Imprinting Polymer

  • Alessandro Lo Presti,
  • Fabricio Nicolas Molinari,
  • Chiara Abate,
  • Enza Fazio,
  • Carmelo Corsaro,
  • Ottavia Giuffrè,
  • Anna Piperno,
  • Giulia Neri and
  • Claudia Foti

23 December 2025

The integration of molecular imprinting technology with electrochemical methods has become fundamental in the development of next-generation sensors. This study explores two different strategies for developing a dopamine-based molecularly imprinted p...

  • Review
  • Open Access
22 Citations
5,643 Views
24 Pages

19 February 2023

Molecularly imprinted polymer (MIP)-based luminescent chemosensors combine the advantages of the highly specific molecular recognition of the imprinting sites and the high sensitivity with the luminescence detection. These advantages have drawn great...

  • Review
  • Open Access
63 Citations
11,146 Views
23 Pages

Molecularly Imprinted Nanomaterials for Sensor Applications

  • Muhammad Irshad,
  • Naseer Iqbal,
  • Adnan Mujahid,
  • Adeel Afzal,
  • Tajamal Hussain,
  • Ahsan Sharif,
  • Ejaz Ahmad and
  • Muhammad Makshoof Athar

26 November 2013

Molecular imprinting is a well-established technology to mimic antibody-antigen interaction in a synthetic platform. Molecularly imprinted polymers and nanomaterials usually possess outstanding recognition capabilities. Imprinted nanostructured mater...

  • Article
  • Open Access
36 Citations
8,341 Views
20 Pages

5 December 2014

A universal label-free detection of bioanalytes can be performed with biomimetic quartz crystal microbalance (QCM) coatings prepared by imprinting strategies. Bulk imprinting was used to detect the endocrine disrupting chemicals (EDCs) known as estra...

  • Review
  • Open Access
25 Citations
7,910 Views
25 Pages

6 January 2023

Molecular imprinting technology is a well-known strategy to synthesize materials with a predetermined specificity. For fifty years, the “classical” approach assumed the creation of “memory sites” in the organic polymer matrix...

  • Article
  • Open Access
8 Citations
9,249 Views
21 Pages

15 June 2016

The creation of label-free biosensors capable of accurately detecting trace contaminants, particularly small organic molecules, is of significant interest for applications in environmental monitoring. This is achieved by pairing a high-sensitivity si...

  • Feature Paper
  • Article
  • Open Access
13 Citations
3,956 Views
14 Pages

Potentiometric Biosensor Based on Artificial Antibodies for an Alzheimer Biomarker Detection

  • Sónia Claúdia Ribeiro,
  • Rúben Fernandes,
  • Felismina T. C. Moreira and
  • Maria Goreti Ferreira Sales

2 April 2022

This paper presents a potentiometric biosensor for the detection of amyloid β-42 (Aβ-42) in point-of-care analysis. This approach is based on the molecular imprint polymer (MIP) technique, which uses covalently immobilised Aβ-42 to cre...

  • Article
  • Open Access
24 Citations
5,668 Views
14 Pages

Selective Adsorption of Quercetin by the Sol-Gel Surface Molecularly Imprinted Polymer

  • Keke Zhi,
  • Zhe Li,
  • Han Luo,
  • Yitong Ding,
  • Feiyan Chen,
  • Yongxiang Tan and
  • Hongrui Liu

11 February 2023

Quercetin, as one of the most biologically active natural flavonoids, is widely found in various vegetables, fruits and Chinese herbs. In this work, molecularly imprinted polymer (MIP) was synthesized through surface molecular imprinting technology w...

  • Article
  • Open Access
33 Citations
7,411 Views
16 Pages

Removal of Toxic Mercury from Petroleum Oil by Newly Synthesized Molecularly-Imprinted Polymer

  • Nor Ain Shahera Khairi,
  • Nor Azah Yusof,
  • Abdul Halim Abdullah and
  • Faruq Mohammad

8 May 2015

In recent years, molecularly-imprinted polymers (MIPs) have attracted the attention of several researchers due to their capability for molecular recognition, easiness of preparation, stability and cost-effective production. By taking advantage of the...

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