Search Results (29)

The imbalance of phosphodiesterase 5 (PDE5) enzyme in the male body, or excessive PDE5 enzyme levels, can occur due to factors such as aging, diseases (e.g., cardiovascular disease, diabetes, depressive disorder), and physical behaviors (e.g., alcoholism, smoking, stress). PDE5 is directly associated with erectile dysfunction disease. Currently, many studies aim to find natural PDE5 inhibitors as an alternative to commercial drugs. This study is the first to demonstrate that the ethanolic leaf extract of D. cochinchinensis exhibits potent PDE5-inhibitory activity. The PDE5-inhibitory activity of five plant parts was evaluated: leaf (IC₅₀ = 1.53 ± 0.12 µg/mL), twig (3.37 ± 0.54), fruit (14.92 ± 2.85), heartwood (19.05 ± 5.60), and bark (16.03 ± 2.92). However, there is still uncertainty about which compounds in leaf extract are responsible for the PDE5 inhibition. Therefore, the purpose of this study is to identify the chemical constituents in the leaf of D. cochinchinensis, including determining which of these compounds may act as PDE5 inhibitors. This study was achieved using at-line LC-QTOF-MS². Full article

This study investigates the vibrational and acoustic properties of Sitka spruce (Picea sitchensis (Bong.) Carr.) and Indian rosewood (Dalbergia latifolia Roxb.), two common musical instrument woods, at moisture contents of 2%, 7%, and 12%. The specimens with dimensions of 400mm (longitudinal) × 25 mm (radial) × 10 mm (tangential) were tested under cantilever beam conditions using non-contact magnetic field excitation to generate sinusoidal and pulse signals. Vibration data were collected via acceleration sensors and FFT analyzers. The test method was based on ASTM D6874-12 standard. Results indicate that increasing moisture content reduces acoustic vibration characteristics, with hardwoods exhibiting higher declines than softwoods. From 2% to 12% moisture content, the first-order sound radiation quality factor of Sitka spruce and Indian rosewood decreased by 15.41% and 15.57%, respectively, while the sound conversion rate declined by 41.91% and 43.21%. Increased moisture content lowers first-order and second-order resonance frequencies, amplitude ratios, dynamic elastic modulus, vibration propagation velocity, acoustic radiation quality factor, and acoustic conversion efficiency, while increasing acoustic impedance and the loss factor. With excitation frequency increases from 100 Hz to 1500 Hz, vibration propagation velocity rises slightly, while the loss factor declines. Full article

Siamese rosewood (Dalbergia cochinchinensis Pierre) is a highly valuable economic tree species in Thailand. This study investigated genetic diversity across 72 tree samples from 17 Thai locations using two genetic markers: the chloroplast maturase K (matK) gene and the nuclear internal transcribed spacer (ITS) region. Analysis of 48 matK and 65 ITS sequences revealed 34 (DcM1–DcM34) and 31 (DcI1–DcI31) haplotypes, respectively. The Saraburi province haplotype DcM10 exhibited the highest genetic divergence, differing by 25 mutational steps from other haplotypes. Phylogenetic analysis incorporating GenBank sequences from other Dalbergia species showed that matK sequences separated D. cochinchinensis into two distinct clades: Clade A, comprising most Thai samples, and Clade B, containing Saraburi samples grouped with sequences from Laos and Cambodia. In contrast, ITS analysis revealed a single monophyletic group. These findings have important applications for conservation strategies, particularly in prioritizing the genetically distinct Saraburi population for protection, and can inform breeding programs to maintain genetic diversity. Additionally, the identified genetic markers could be developed into tools for timber authentication to combat illegal logging, while the revealed population structure can guide reforestation efforts and international conservation collaboration with Laos and Cambodia. Full article

During the manufacturing of wooden musical instruments, offcut wood pieces are inevitably generated. This study explores the potential of utilizing three types of these small offcut wood pieces, mahogany, maple, and rosewood, by converting them into polyurea through liquefied wood technology by proposing a novel approach to synthesizing bio-based polyurea. This polyurea is a durable polymer, offering long-term carbon fixation and thereby contributing to environmental sustainability. In this study, various liquefaction conditions as parameters, including the temperature, sulfuric acid content, mix solvent ratio, and liquefaction time, were investigated in relation to polyurea film properties. The relationship between the mechanical and thermal properties of the resulting films and the characteristics of the liquefied product was investigated. Notably, when the hydroxyl value of the liquefied product exceeded 300, the resulting polyurea derived from the liquefied product exhibited a high tensile strength of 25 MPa. In contrast, when the hydroxyl value was below 300, the polyurea derived from the liquefied product displayed a strain value of up to 150%, alongside an increased thermal decomposition temperature. These findings suggest that the properties of polyurea can be effectively tuned by manipulating the characteristics of the liquefied product, offering a promising approach to enhancing the value of offcut wood in instrument manufacturing. Full article

Dalbergia nigra is a long-living tree endemic to the Atlantic Rain Forest. Due to its high commercial value, this species has been widely exploited for timber production and is now endangered. It is widely known that understanding patterns of genetic structure is paramount for conserving threatened species. We analyzed the genetic diversity of 140 individuals from four different forest fragments in the southern region of Bahia, Brazil, to verify the possible effects of fragmentation on these populations and provide information for conservation initiatives. High polymorphism levels were detected from the genotyping of nine microsatellite loci (mean H_E = 0.733). All populations showed high genetic diversity; however, a reduction of genetic diversity was detected in each population (H_O < H_E). The average fixation index was high and significant (f = 0.167), which could be due to the occurrence of inbreeding, the Wahlund effect, reproductive system, or from null alleles. Genetic differentiation among populations was high (mean θ_P = 0.118), suggesting strong isolation, a pattern consistent with historically low gene flow. The Bayesian analysis revealed five different genetic groups, among which three groups correspond to three different forest fragments, and two groups showed the genetic subdivision of individuals from the other forest fragment. Based on our results, the suggested conservation strategy for D. nigra populations in the southern region of Bahia, Brazil, involves high environmental investments to protect all sampled forest fragments and individuals. Another strategy would be to collect seeds from all individuals from the sampled fragments and start a new population with human interference in its evolutive history inside a protection unit. Full article

The underlying genetic susceptibility for Alzheimer’s disease (AD) is not yet fully understood. The heterogeneous nature of the disease challenges genetic association studies. Endophenotype approaches can help to address this challenge by more direct interrogation of biological traits related to the disease. AD endophenotypes based on amyloid-β, tau, and neurodegeneration (A/T/N) biomarkers and cognitive performance were selected from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) cohort (N = 1565). A genome-wide association study (GWAS) of quantitative phenotypes was performed using an SNP main effect and an SNP by Diagnosis interaction (SNP × DX) model to identify disease stage-specific genetic effects. Nine loci were identified as study-wide significant with one or more A/T/N endophenotypes in the main effect model, as well as additional findings significantly associated with cognitive measures. These nine loci include SNPs in or near the genes APOE, SRSF10, HLA-DQB1, XKR3, and KIAA1671. The SNP × DX model identified three study-wide significant genetic loci (BACH2, EP300, and PACRG-AS1) with a neuroprotective effect in later AD stage endophenotypes. An endophenotype approach identified novel genetic associations and provided insight into the molecular mechanisms underlying the genetic associations that may otherwise be missed using conventional case-control study designs. Full article

While numerous studies have examined microbial attacks on waterlogged archaeological wood, limited information is available regarding microbial attacks in waterlogged tropical hardwoods submerged in marine environments. In this context, we explored microbial attacks in waterlogged archaeological rosewood (Dalbergia species), a tropical hardwood species that was submerged in the Yellow Sea for approximately 700 years, using various microscopic techniques and next-generation sequencing (NGS) methods. Based on morphological features, Type-I soft rot decay was identified as the main decay type. Most fibers in waterlogged archaeological rosewood studied were gelatinous (G) fibers of tension wood and the mode of soft rot decay differed from fibers without the G-layer. Differences in decay resistance between vessel/axial parenchyma cells and fibers were not obvious. Vestured- and simple pit membranes showed higher decay resistance than vessel and axial parenchyma cell walls, respectively. Microbial community analysis by NGS revealed the dominance of Ascomycota and Basidiomycota in the fungal community. Various bacterial communities were also identified, although no prominent signs of bacterial decay were noted. The identified bacterial communities markedly differed from those reported previously in terms of their composition and abundance. Together, our results offer detailed insights into the microbial types and communities responsible for degrading waterlogged archaeological rosewood, contributing to a better understanding of microbial attacks in tropical hardwoods exposed to marine environments. Full article

As influenced by agricultural practices, soil organic matter (SOM) stability is imperative in maintaining soil fertility and crop production. Integrated soil management practices have been recommended for soil fertility improvement by enhancing soil organic matter. We examined the SOM stability under integrated soil management practices for six consecutive cropping seasons in the high agricultural potential area of the Central Highlands of Kenya. The experimental design was a complete randomized block design with fourteen treatments replicated four times. The treatments were minimum (Mt) and conventional tillage (Ct) combined with sole mineral fertilizer (Mf), crop residue combined with mineral fertilizer (RMf), crop residue combined with mineral fertilizer and animal manure (RMfM), crop residue combined with animal manure and Dolichos Lablab L. intercrop (RML), crop residue combined with Tithonia diversifolia and animal manure (RTiM), and crop residue combined with Tithonia diversifolia and phosphate rock (Minjingu) (RTiP), as well as a control (no inputs). SOC was higher in treatments with organic inputs and a combination of organic and inorganic inputs. Treatments with sole mineral fertilizer and no input recorded lower SOC amounts. The C functional groups followed the sequence: alkyl C (53%) > O-alkyl C (17%) > aromatic C (9%) > carboxyl C (8%) > methoxyl C (7%) > phenolic C (6%). The alkyl C proportion was higher in organic inputs treatments, while O-alkyl C was higher in organic and inorganic fertilizer treatment combinations. Methoxyl C, aromatic C, and phenolic C proportion of SOC was greater in crop residue and mineral fertilizer combination, while carboxylic C was lower than the control in most treatments. In addition, the organic inputs treatments had a higher alkyl C/O-alkyl C ratio, increased aliphaticity, and higher hydrophobicity. Applying organic fertilizers individually or in combination with inorganic fertilizers could potentially increase C storage in the soil, thereby enhancing SOC stocks. Full article

To enhance the stability of wood and decrease restrictions on its use in the furniture industry, hydrophobic modification can be employed to confer waterproof, anti-fouling, and self-cleaning properties. The present study outlines the preparation of silica sol using the sol–gel method, followed by impregnation and chemical vapor deposition methods to modify the sol. After grafting 1H,1H,2H,2H-perfluoro-decyl trichlorosilane (FDTS), hydrophobic and superhydrophobic properties were imparted to the wood substrate. To explore the correlation between the surface properties of the wood substrate and superhydrophobic coatings, the densities, porosities, and surface roughness of various tree species were compared. The results showed that the sol–gel method successfully constructed hydrophobic coatings on different wood substrates, with six samples (poplar, elm, toon wood, paulownia, ashtree, and black walnut) achieving superhydrophobic surfaces, with densities ranging from 0.386 to 0.794 g/cm³, porosity ranging from 13.66 to 42.36%, roughness ranging from 4.660 to 11.244 um, and maximum water contact angle of 165.2°. Whereas beech and rosewood only reach the hydrophobic surface. Although the coatings demonstrated good resistance to water, pollutants, self-cleaning, and chemical agents, further improvements are necessary to enhance mechanical wear resistance. Full article

Dalbergia odorifera (D. odorifera), commonly named the fragrant rosewood, is one of the second-level protected wild plants in China, and one of 34 species of rosewood in five genera and eight categories in the National Standard of China. As a kind of traditional Chinese medicine (TCM), it plays an important role in the pharmaceutical industry, including the treatment of cardiovascular diseases, rheumatic pain, etc. With the continuous expansion of the planting area of D. odorifera, the diseases and pests of D. odorifera become more and more serious, among which leaf-eating pests are the most serious. In this study, ultraviolet rays and microwaves were used to mutagenize Beauveria bassiana (B. bassiana) strain HNCMBJ-P-01, and excellent mutant strains with high spore yield and high virulence were screened out, and then they were prepared into a wettable powder for forest control experiments to study their biocontrol effects. The virulence screening test showed that the virulence of strain HBWB-44 was the strongest, and the 10 day corrected mortality rate was 80.00%, and the lethal time was 5.622 days. The results of biological control test showed that the control effect of B. bassiana wettable powder 100 times solution reached 60.89%, second only to the botanical fungicide matrine. Generically, The B. bassiana that we screened and mutated showed a good killing effect on Plecoptera bilinealis (P. bilinealis), and the wettable powder produced by it showed a good control effect on the leaf-eating pests of D. odorifera. The application of fungal insecticides in plantations has a good prospect for controlling the occurrence of leaf-eating pests of D. odorifera. Full article

Soil health and fertility are indexed by soil organic carbon (SOC) content. Soil management through good agricultural practices that enhance and sustain SOC is vital for soil fertility. We examined the influence of soil fertility management strategies on SOC concentrations in different particle size fractions under a maize cropping system. We laid the experiment in a randomized complete block design, with 14 treatments replicated 4 times, and used the following inputs: inorganic fertilizer (Mf), maize residue +inorganic fertilizer (RMf), maize residue + inorganic fertilizer, and goat manure (RMfM), maize residue + goat manure + Dolichos Lablab L intercrop (RML), maize residue + Tithonia diversifolia + goat manure (RTiM) and maize residue + Tithonia diversifolia + phosphate rock (Minjingu) (RTiP) and a Control (no inputs) under reduced tillage (Mt) or conventional tillage (Ct). Soil samples were collected from two depths, 0–5 cm, and 5–15 cm. We determined the content of organic carbon in three physical fractionation: coarse fractions (1.7 mm, 500 µm sieve), medium fractions (250 µm and 90 µm), and a fine fraction (75 µm). Results showed that treatment with maize residues, goat manure, and legume intercrop (MtRML and CtRML) resulted in higher SOC in most fractions, irrespective of the soil depth. The SOC concentration significantly (p < 0.0001) differed across treatments and depth. It was followed by maize residue, goat manure, and inorganic fertilizer treatments, and the least was inorganic fertilizer treatment. This underpins the importance of manure application and crop residue retention in increasing SOC amounts. Reduced tillage did not influence the SOC amounts during the sampling period in the experimentation site. This study highlights the possibility of improving agricultural productivity by improving soil fertility through a combination of different agricultural soil fertility amendments in Sub-Saharan Africa. Full article

Dalbergia tonkinensis is being promoted in Vietnam for the future supply of prized wood for furniture and chemical extraction. Expansion of the plantation area requires a reliable source of quality seed. This study evaluates the field performance of progeny from mature mother trees in natural forests and urban environments. Trials were established in Tan Son and Doan Hung districts of Phu Tho province and assessed 3 years later. There were significant differences in growth and survival between provenances. The best families reached heights of >3.5 m and came from mother trees in a natural forest. The number of leaflets per leaf on mother trees was positively correlated with height (Ht) and diameter at breast height (Dbh) of the trial trees. The individual heritabilities (ĥ²) for Ht and Dbh were 0.39 and 0.49 for Tan Son, and 0.33 and 0.48 for Doan Hung, respectively. The coefficient of additive variation (CV_A) of Ht and Dbh were 36% and 58% for Tan Son, and 23% and 30% for Doan Hung, respectively. Interactions between the growth traits in the two trials were strongly correlated (R² = 0.88 for Ht, 0.90 for Dbh). These results identify D. tonkinensis gene sources with advantages for early growth performance in plantations. These superior genetics can be used for seed orchards, clonal propagation and for implementing a breeding program. Full article

The genus Dalbergia contains more than 200 species, several of which are trees that produce traditional medicines and extremely high-value timber commonly referred to as rosewood. Due to the rarity of these species in the wild, the high value of the timber, and a growing international illicit trade, CITES (Convention on International Trade in Endangered Species of Wild Fauna and Flora) has listed the entire genus in appendix II and the species Dalbergia nigra in appendix I because species in this genus are considered at risk of extinction. Given this, and the fact that species or even genus level determination is nearly impossible from cut timber morphology, alternative molecular methods are needed to identify and track intercepted rosewood. To better identify rosewood using molecular methods, we sequenced and assembled eight chloroplast genomes including D. nigra as well as conducted comparative analyses with all other available chloroplast genomes in Dalbergia and closely related lineages. From these analyses, numerous repeats including simple sequence repeats (SSR) and conserved nucleotide polymorphisms unique to subclades within the genus were detected. From phylogenetic analysis based on the CDS from 77 chloroplast genes, the groups Siam rosewood and scented rosewood resolved as monophyletic, supporting the morphological traits used to delimit these species. In addition, several instances of paraphyly and polyphyly resulting from mismatches between taxonomic determinations and phylogenetic tree topology were identified. Ultimately, the highly variable regions in the chloroplast genomes will provide useful plastid markers for further studies regarding the identification, phylogeny, and population genetics of Dalbergia species, including those frequently intercepted in illegal trade. Full article

The study aimed to use a statistical method of mixture design to optimize the antimicrobial activity of Tea Tree (Melaleuca alternifolia), Rosewood (Aniba rosaeodora), and Lavender (Lavandula hybrida) essential oils against Escherichia coli PCM 2057, Listeria monocytogenes PCM 2191, and Rhodotorula mucilaginosa EPSC001. The antimicrobial activity of used essential oils and their mixtures were evaluated by the disc diffusion method. Moreover, the antioxidant activity of tested essential oils was determined by the DPPH• and CUPRAC methods, and total phenolic content was measured using the Folin–Ciocalteu method. Tea tree essential oil was characterized by the highest total phenolic content (0.59 ± 0.05 mg GAE/g) followed by lavender oil (0.27 ± 0.05 mg GAE/g), and rosewood oil (0.11 ± 0.02 mg GAE/g). The first two oils also had similar antioxidant activity. Furthermore, essential oil from the tea tree exhibited the highest antimicrobial activity against tested microorganisms, and based on the mixture design approach, the aforementioned volatile oil participated in optimized mixtures in the greatest amount. Full article

The current scientific literature lacks an adequate description of hardware used to machine timber. Traditional woodworking and metals fabrication consists of tungsten carbide (TC) inserts. In this work, the authors investigate the influence of cutting tool geometry on the resulting surface roughness of timber samples. A variety of wood types were used in these studies to provide broad information on the correlation between the cutting tools used and resulting surface morphology. The cutting tools were prepared on a computer numerical control (CNC) lathe and roughness average (R_a) and average maximum peak to valley height of the profile (R_z) parameters were measured by contact stylus. The tip radius of the TC inserts used was determined to be the most significant factor that impacted R_a and R_z. In summary, we found that the tip radius of the TC insert was inversely proportional to the roughness level, indicating that a flatter TC insert cutting end results in a smoother wood surface. Full article