Search Results (20,941)

Constipation is a prevalent gastrointestinal disorder that significantly impairs quality of life. While pharmacological agents such as loperamide are widely used to induce constipation in experimental models, there is increasing interest in natural alternatives for alleviating intestinal dysfunction. In this study, we investigated the laxative effects of soybean powder fermented by Bacillus subtilis DKU_09 in a loperamide-induced rat model of constipation. The probiotic strain was isolated from cheonggukjang, a traditional Korean fermented soybean paste, and its identity was confirmed through 16S rRNA sequencing. Fermented soybean powder was characterized morphologically via scanning electron microscopy and chemically via HPLC to assess its isoflavone content. Rats were administered loperamide (5 mg/kg) for four days to induce constipation and were then treated with fermented soybean powder at doses of 100, 200, or 300 mg/kg. No pharmacological laxatives (e.g., PEG) were used as a positive control; instead, values from the treatment groups were compared with those from the loperamide-only constipation group. Key outcomes of fecal output, water content, colonic fecal retention, and gastrointestinal transit ratio were measured. The fermented product significantly improved stool frequency and moisture content, reduced colonic fecal retention, and restored gastrointestinal transit in a dose-dependent manner. Notably, the 300 mg/kg group demonstrated nearly complete recovery of fecal parameters without affecting body weight. Statistical analysis was performed using one-way ANOVA followed by Tukey’s post hoc test. These findings suggest that Bacillus subtilis-fermented soybean powder exerts synergistic laxative effects through the combined action of probiotic viability and fermentation-enhanced bioactive compounds such as aglycone isoflavones. This study supports the potential use of fermented soybean-based nutraceuticals as a natural and safe intervention for constipation and gastrointestinal dysregulation. Full article

Bi₆Fe₂Ti₃O₁₈ (BFTO) ceramics were synthesized via a solid-state reaction route using stoichiometric amounts of Bi₂O₃, TiO₂, and Fe₂O₃ powders. A thermal analysis of the powder mixture was conducted to optimize the heat treatment parameters. Energy-dispersive X-ray spectroscopy (EDS) confirmed the conservation of the chemical composition following calcination. Final densification was achieved through hot pressing. The crystal structure of the sintered samples, examined via X-ray diffraction at room temperature, revealed a tetragonal symmetry for BFTO ceramics sintered at 850 °C. Electron backscatter diffraction (EBSD) provided detailed insight into the crystallographic orientation and microstructure. Broadband dielectric spectroscopy (BBDS) was employed to investigate the dielectric response of BFTO ceramics over a frequency range of 10 mHz to 10 MHz and a temperature range of −30 °C to +200 °C. The temperature dependence of the relative permittivity (ε_r) and dielectric loss tangent (tan δ) were measured within a frequency range of 100 kHz to 900 kHz and a temperature range of 25 °C to 570 °C. The impedance data obtained from the BBDS measurements were validated using the Kramers–Kronig test and modeled using the Kohlrausch–Williams–Watts (KWW) function. The stretching parameter (β) ranged from ~0.72 to 0.82 in the impedance formalism within the temperature range from 200 °C to 20 °C. Full article

The phase equilibria of the Si-C-Cu ternary system at 700 °C and 810 °C were experimentally investigated for the first time. Fifteen key alloys were prepared via powder metallurgy and analyzed using X-ray diffraction (XRD), scanning electron microscopy (SEM), and electron probe microanalysis (EPMA). Isothermal sections were constructed based on the identified equilibrium phases. At 700 °C, eight single-phase regions and six three-phase regions—(C)+(Cu)+hcp, (C)+hcp+γ-Cu₃₃Si₇, (C)+γ-Cu₃₃Si₇+SiC, γ-Cu₃₃Si₇+SiC+ε-Cu₁₅Si₄, SiC+ε-Cu₁₅Si₄+η-Cu₃Si(ht), and SiC+(Si)+η-Cu₃Si(ht)—were determined. At 810 °C, nine single-phase regions and seven three-phase regions were identified. The solubility of C and Si/Cu in the various phases was quantified and found to be significantly higher at 810 °C compared to 700 °C. Key differences include the presence of the bcc (β) and liquid phases at 810 °C. The results demonstrate that higher temperatures promote increased mutual solubility and reaction tendencies among Cu, C, and Si. Motivated by these findings, the influence of vacuum hot pressing parameters on SiC-fiber-reinforced Cu composites (SiC_f/Cu) was investigated. The optimal processing condition (1050 °C, 60 MPa, 90 min) yielded a high bending strength of 998.61 MPa, attributed to enhanced diffusion and interfacial bonding facilitated by the high-temperature phase equilibria. This work provides essential fundamental data for understanding interactions and guiding processing in SiC-reinforced Cu composites. Full article

Aiming at the lightweight design of a bridge-shed integration structure, this paper presents a three-layered absorbing system in which a part of the sand cushion is replaced by expanded polystyrene (EPS) geofoam and the reinforced concrete (RC) protective slab is arranged above the sand cushion to enhance the composite system’s safety. A three-dimensional Smoothed Particle Hydrodynamics–Finite Element Method (SPH-FEM) coupled numerical model is developed in LS-DYNA (Livermore Software Technology Corporation, Livermore, CA, USA, version R13.1.1), with its validity rigorously verified. The dynamic response of rockfall impacts on the shed slab with composite cushions of various thicknesses is analyzed by varying the thickness of sand and EPS materials. To optimize the cushion design, a specific energy dissipation ratio (SEDR), defined as the energy dissipation rate per unit mass (η/M), is introduced as a key performance metric. Furthermore, the complicated interactional mechanism between the rockfall and the optimum-thickness composite system is rationally interpreted, and the energy dissipation mechanism of the composite cushion is revealed. Using logistic regression, the ultimate stress state of the reactive powder concrete (RPC) slab is methodically analyzed, accounting for the speed and mass of the rockfall. The results are indicative of the fact that the composite cushion not only has less dead weight but also exhibits superior impact resistance compared to the 90 cm sand cushions; the impact resistance performance index SEDR of the three-layered absorbing system reaches 2.5, showing a remarkable 55% enhancement compared to the sand cushion (SEDR = 1.61). Additionally, both the sand cushion and the RC protective slab effectively dissipate most of the impact energy, while the EPS material experiences relatively little internal energy build-up in comparison. This feature overcomes the traditional vulnerability of EPS subjected to impact loads. One of the highlights of the present investigation is the development of an identification model specifically designed to accurately assess the stress state of RPC slabs under various rockfall impact conditions. Full article

This study aimed to evaluate the effects of three drying methods, namely sun drying, microwave–vacuum drying, and hot-air-oven drying, on the physical and nutritional properties of cricket powder for use in poultry feed. The results showed that the drying method significantly affected color parameters (L*, a*, and b*; p < 0.05), and particle size distribution at 850 µm and 250 µm (p = 0.04 and p = 0.02, respectively). Microwave–vacuum drying produced the lightest powder with a higher proportion of coarse particles, while sun drying resulted in a darker color and greater particle retention at 850 µm. Hot-air-oven drying yielded the lowest moisture content (1.99%) and the highest gross energy (6126.43 kcal/kg), with no significant differences observed in crude protein (p = 0.61), ether extract (p = 0.08), crude fiber (p = 0.14), ash (p = 0.22), or amino acid profiles (p > 0.05). These findings indicate that all drying methods preserved the nutritional value of cricket powder, and based on the overall results, hot-air-oven drying is the most suitable method for producing high-quality cricket meal with optimal physical properties and feed value, while also providing a practical balance between drying efficiency and cost. Full article

Astragalus sinicus, a key leguminous green manure widely cultivated in Southern China’s rice-based cropping systems, plays a pivotal role in sustainable agriculture by enhancing soil organic matter sequestration, improving rice yield, and elevating grain quality. The symbiotic nitrogen-fixing association between A. sinicus and its matching rhizobia is fundamental to its agronomic value; however, suboptimal inoculant efficiency and field application methodologies constrain its full potential. To address these limitations, we conducted a multi-phase study involving (1) rhizobial strain screening under controlled greenhouse conditions, (2) an optimized lyophilization protocol evaluating cryoprotectant (trehalose, skimmed milk powder and others), and (3) seed pelleting trails with rhizobial viability and nodulation assessments over different storage periods. Our results demonstrate that Mesorhizobium huakuii CCBAU 33470 exhibits a superior nitrogen-fixing efficacy, significantly enhancing key traits in A. sinicus, including leaf chlorophyll content, tiller number, and aboveground biomass. Lyophilized inoculants prepared with cryoprotectants (20% trehalose or 20% skimmed milk powder) maintained >90% bacterial viability for 60 days and markedly improved nodulation capacity relative to unprotected formulations. The optimized seed pellets sustained high rhizobial loads (5.5 × 10³ cells/seed) with an undiminished viability after 15 days of storage and nodulation ability after 40 days of storage. This integrated approach of rhizobial selection, inoculant formulation, and seed coating overcomes cultivation bottlenecks, boosting symbiotic nitrogen fixation for A. sinicus cultivation. Full article

The dairy industry generates significant amounts of wastewater, including microfiltration (MF) retentate, a byproduct thickened with organic and inorganic pollutants. This study focuses on the treatment of two times concentrated MF retentate using a hybrid system based on biological treatment in a sequential batch reactor (SBR) and adsorption on activated carbon. The first stage involved cross-flow microfiltration using a 0.2 µm PVDF membrane at 0.5 bar, resulting in reductions of 99% in turbidity and 79% in chemical oxygen demand (COD), as well as a partial reduction in conductivity. The second stage involved 24-h biological treatment in a sequential batch reactor (SBR) with activated sludge (activated sludge index: 80 cm³/g, MLSS 2500 mg/dm³), resulting in further reductions in COD (62%) and TOC (30%), as well as the removal of 46% of total phosphorus (TP) and 35% of total nitrogen (TN). In the third stage, the decantate underwent adsorption in a column containing powdered activated carbon (PAC; 1 g; S_(BET) = 969 m² g⁻¹), reducing the concentrations of key indicators to the following levels: COD 84%, TOC 70%, TN 77%, TP 87% and suspended solids 97%. Total pollutant retention ranged from 24.6% to 97.0%. These results confirm that the MF–SBR–PAC system is an effective, compact solution that significantly reduces the load of organic and biogenic pollutants in MF retentates, paving the way for their reuse or safe discharge into the environment. Full article

Directed Energy Deposition is an additive manufacturing subgroup that uses a laser beam to melt the wire or powder to create a melt pool. In the current study, a scientometric analysis has been carried out to analyze the contribution of countries, publication type analysis, distribution of publications over the years, keywords analysis, author analysis, cited journal, categories, institutes of publication, and report the practical implications. Firstly, the database was extracted from the Web of Science and then post-processed with CiteSpace 6.2.R4 and VOSviewer 1.6.20 software. Afterward, the associated results had been extracted and reported. It was found that China is the leader according to publication, followed by the USA and Germany, which mostly published their achievements in article and proceeding paper formats, which are increasing annually. According to the keywords, additive manufacturing, Laser Metal Deposition, and fabrication are the most commonly used. Based on the CiteSapce and VOSviewer results, Lin, Xin and Huang, Weidong are the authors with the highest publication rates. In addition, Additive Manufacturing, Materials & Design, and Materials Science and Engineering: A are the most cited journals, and regarding the categories, materials science, multidisciplinary, applied physics, and manufacturing engineering are the most commonly used DED processes. Northwestern Polytechnical University, Fraunhofer Gesellschaft, and the United States Department of Energy (DOE) have performed the most research in the field of DED. Full article

This study aimed to develop an innovative resin composite with anti-biofouling properties, tailored to prosthesis fabrication in dentistry using a digital light processing (DLP) 3D-printing technique. The resin composite was formulated using a blend of dental monomers, with the integration of 2-methacryloyloxylethyl phosphorylcholine (MPC) with anti-biofouling behavior and γ-MPS-treated silica-zirconia powder for simultaneous mechanical reinforcement. The overall characterization of the resin composite was carried out using various contents of MPC incorporated into the resin (0–7 wt%) for examining the rheological behavior, photopolymerization, flexural strength/modulus, microstructure and anti-biofouling efficiency. The resin composite demonstrated a significant reduction in bacterial adhesion (97.4% for E. coli and 86.5% for S. aureus) and protein adsorption (reduced OD value from 1.3 ± 0.4 to 0.8 ± 0.2) with 7 wt% of MPC incorporation, without interfering with photopolymerization to demonstrate potential suitability for 3D printing without issues (p < 0.01, and p < 0.05, respectively). The incorporation and optimization of γ-MPS-treated silica-zirconia powder (10–40 vol%) enhanced mechanical properties, leading to a reasonable flexural strength (103.4 ± 6.1 MPa) and a flexural modulus (4.3 ± 0.4 GPa) at 30 vol% (n = 6). However, a further increase to 40 vol% resulted in a reduction in flexural strength and modulus; nevertheless, the results were above ISO 10477 standards for dental materials. Full article

Rapid pavement repair demands materials that combine accelerated strength gains, dimensional stability, long-term durability, and sustainability. However, finding materials or formulations that offer these balances remains a critical challenge. This study systematically evaluates two polymer-modified belitic calcium sulfoaluminate (CSA) concretes—CSAP (powdered polymer) and CSA-LLP (liquid polymer admixture)—against a traditional Type III Portland cement (OPC) control under both laboratory and realistic outdoor conditions. Laboratory specimens were tested for fresh properties, early-age and later-age compressive, flexural, and splitting tensile strengths, as well as drying shrinkage according to ASTM standards. Outdoor 5 × 4 × 12-inch slabs mimicking typical jointed plain concrete panels (JPCPs), instrumented with vibrating wire strain gauges and thermocouples, recorded the strain and temperature at 5 min intervals over 16 weeks, with 24 h wet-burlap curing to replicate field practices. Laboratory findings show that CSA mixes exceeded 3200 psi of compressive strength at 4 h, but cold outdoor casting (~48 °F) delayed the early-age strength development. The CSA-LLP exhibited the lowest drying shrinkage (0.036% at 16 weeks), and outdoor CSA slabs captured the initial ettringite-driven expansion, resulting in a net expansion (+200 µε) rather than contraction. Approximately 80% of the total strain evolved within the first 48 h, driven by autogenous and plastic effects. CSA mixes generated lower peak internal temperatures and reduced thermal strain amplitudes compared to the OPC, improving dimensional stability and mitigating restraint-induced cracking. These results underscore the necessity of field validation for shrinkage compensation mechanisms and highlight the critical roles of the polymer type and curing protocol in optimizing CSA-based repairs for durable, low-carbon pavement rehabilitation. Full article

The construction industry plays a major role in the consumption of natural resources and the generation of waste. Construction and demolition waste (CDW) is produced in substantial volumes globally and is widely available. Its accumulation poses serious challenges related to storage and disposal, highlighting the need for effective strategies to mitigate the associated environmental impacts of the sector. This investigation intends to evaluate the influence of mixed CDW on the physical, mechanical, and durability properties of mortars with CDW partially replacing Portland cement, and allow performance comparisons with mortars produced with fly ash, a commonly used supplementary binder in cement-based materials. Thus, three mortar formulations were developed (reference mortar, mortar with 25% CDW, and mortars with 25% fly ash) and several characterization tests were carried out on the CDW powder and the developed mortars. The work’s principal findings revealed that through mechanical grinding processes, it was possible to obtain a CDW powder suitable for cement replacement and with good indicators of pozzolanic activity. The physical properties of the mortars revealed a decrease of about 10% in water absorption by immersion, which resulted in improved performance regarding durability, especially with regard to the lower carbonation depth (−1.1 mm), and a decrease of 51% in the chloride diffusion coefficient, even compared to mortars incorporating fly ash. However, the mechanical performance of the mortars incorporating CDW was reduced (25% in terms of flexural strength and 58% in terms of compressive strength), but their practical applicability was never compromised and their mechanical performance proved to be superior to that of mortars incorporating fly ash. Full article

Although cemented carbides have been manufactured by the powder metallurgy (P/M) technology for over a century now, systematic developmental efforts are still underway. In the present study, tool life improvements in metal grooving applications are the key objective. Four PVD-coated cemented carbides compositions, dedicated to groove steel, stainless steel, cast iron, and aluminium alloys, have been newly designed, along with their manufacturing conditions. Physical, mechanical and chemical characteristics—such as sintered density, modulus of elasticity, hardness, fracture toughness, WC grain size, and the chemical composition of the substrate material, as well as the chemical composition, microhardness, structure, and thickness of the coatings—have been studied. A series of grooving tests have also been conducted to assess whether modifications to the thus far marketed tool materials, tool geometries, and coatings can improve cutting performance. In order to compare the laboratory and application properties of the investigated materials with currently produced by reputable companies, commercial inserts have also been tested. The experimental results obtained indicate that the newly developed grooving inserts exhibit excellent microstructural characteristics, high hardness, fracture toughness, and wear resistance and that they show slightly longer tool life compared to the commercial ones. Full article

This study reports on the magnetic properties of commercial cornflakes, which are primarily influenced by the iron content. An initial analysis of X-ray fluorescence on a brand of cornflakes evidenced the presence of a high concentration of Cl and up to 10.9 mg/100 g of Fe. After the extraction of iron from the cornflakes of two different brands, as iron filings, X-ray diffraction measurements indicate the presence of crystals of elemental iron, and no traces of other crystals of iron-derived compounds were found. The Fourier Transform Infrared analysis on the iron filings does not show any binding between iron and oxygen, which further discards the presence of iron oxides. The magnetic hysteresis loops of whole powdered cornflakes exhibit weak Langevin-like magnetizations, which principally correspond to the iron used as a fortification element. The diamagnetic behavior of the higher organic material content significantly attenuates this magnetic response. The hysteresis loops of the iron filings reached magnetic saturations 1% and 5% lower than those of a pure iron sample. Additionally, the indirect measurement of magnetic susceptibility of the iron filings by magneto-thermograms revealed only one Curie transition very close to 771 °C, which corresponds to pure elemental iron. Full article

TiAl alloy offers advantages including low density, high specific strength and stiffness, and excellent high-temperature creep resistance. It is widely used in the aerospace, automotive, and chemical sectors, as well as in other fields. However, at temperatures of 800 °C and above, it forms a porous oxide film predominantly composed of TiO₂, which fails to provide adequate protection. Applying high-temperature protective coatings is therefore essential. Oxides demonstrating protective efficacy at elevated temperatures include Al₂O₃, Cr₂O₃, and SiO₂. The Pilling–Bedworth Ratio (PBR)—defined as the ratio of the volume of the oxide formed to the volume of the metal consumed—serves as a critical criterion for assessing oxide film integrity. A PBR value greater than 1 but less than 2 indicates superior film integrity and enhanced oxidation resistance. Among common oxides, Al₂O₃ exhibits a PBR value within this optimal range (1−2), rendering aluminum-based compound coatings the most extensively utilized. Aluminum coatings can be applied via methods such as pack cementation, thermal spraying, and hot-dip aluminizing. Pack cementation, being the simplest to operate, is widely employed. In this study, a powder mixture with the composition Al:Al₂O₃:NH₄Cl:CeO₂ = 30:66:3:1 was used to aluminize γ-TiAl intermetallic compound specimens via pack cementation at 600 °C for 5 h. Subsequent isothermal oxidation at 900 °C for 20 h yielded an oxidation kinetic curve adhering to the parabolic rate law. This treatment significantly enhanced the high-temperature oxidation resistance of the γ-TiAl intermetallic compound, thereby broadening its potential application scenarios. Full article

Agriculture is one of the most important sectors of the global economy, but it increasingly faces sustainability challenges in meeting rising food demands. The intensive use of mineral fertilizers not only improves yields, but also causes negative environmental impacts such as increasing greenhouse gas emissions, water eutrophication, and soil degradation. To develop more sustainable solutions, the focus is on organic fertilizers, which are produced using waste and biostimulants such as amino acids. The aim of this study was to develop and characterize liquid nitrogen–calcium–magnesium fertilizers produced by decomposing dolomite with nitric acid followed by further processing and to enrich them with a powdered amino acid concentrate Naturamin-WSP and liquid extracts from digestate, a by-product of biogas production. Nutrient-rich extracts were obtained using water and potassium hydroxide solutions, with the latter proving more effective by yielding a higher organic carbon content (4495 ± 0.52 mg/L) and humic substances, which can improve soil structure. The produced fertilizers demonstrated favourable physical properties, including appropriate viscosity and density, as well as low crystallization temperatures (eutectic points from –3 to –34 °C), which are essential for storage and application in cold climates. These properties were achieved by adjusting the content of nitrogenous compounds and bioactive extracts. The results of the study show that liquid fertilizers enriched with organic matter can be an effective and more environmentally friendly alternative to mineral fertilizers, contributing to the development of the circular economy and sustainable agriculture. Full article