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4 Results Found

  • Review
  • Open Access
14 Citations
7,026 Views
28 Pages

α-lipoic acid is a naturally occurring compound with potent antioxidant properties that helps protect cells and tissues from oxidative stress. Its incorporation into nanoplatforms can affect factors like bioavailability, stability, reactivity,...

  • Article
  • Open Access
9 Citations
3,684 Views
15 Pages

5 August 2020

The amphiphilic copolymers of poly(ethylene glycol) methyl ether methacrylate (MPEGMA) and alkyne functionalized 2-hydroxyethyl methacrylate (AlHEMA) were synthesized by controlled atom transfer radical polymerization (ATRP). The reactions were carri...

  • Article
  • Open Access
558 Views
18 Pages

25 November 2025

Readily degradable low-dose hydrate inhibitors are of great significance for flow assurance in the petroleum industry. Recently, α-lipoic acid (LA) was shown to undergo ring-opening reaction via reversible addition–fragmentation chain-tra...

  • Article
  • Open Access
12 Citations
7,074 Views
15 Pages

Amelioration of Metal-Induced Cellular Stress by α-Lipoic Acid and Dihydrolipoic Acid through Antioxidative Effects in PC12 Cells and Caco-2 Cells

  • Kaniz Fatima Binte Hossain,
  • Mahmuda Akter,
  • Md. Mostafizur Rahman,
  • Md. Tajuddin Sikder,
  • Md. Shiblur Rahaman,
  • Shojiro Yamasaki,
  • Goh Kimura,
  • Tomomi Tomihara,
  • Masaaki Kurasaki and
  • Takeshi Saito

α-Lipoic acid (ALA) and its reduced form dihydrolipoic acid (DHLA) are endogenous dithiol compounds with significant antioxidant properties, both of which have the potential to detoxify cells. In this study, ALA (250 μM) and DHLA (50 μM) were applied...