Search Results (2,825)

Home has been recognized as a health infrastructure through hospital-at-home, home care, and direct-to-consumer wellness and fitness products. However, the patient home environment has been largely overlooked by healthcare as a means to improve therapy outcomes for difficult-to-treat chronic conditions, such as migraine; high-impact pain; and treatment-resistant depression, anxiety, or insomnia. Growing research evidence enables the formulation of a therapeutic home environment standard consisting of three pillars: biophilic design, indoor environmental quality, and intentional self-care spaces that serve as habit cues and foster sleep hygiene, stress management, relaxation, physical activity, and social interactions. Together, these environmental and behavioral interventions can transform real-world inputs into clinical benefits through autonomic, circadian, and emotional regulation. We also highlight the converging roles of self-management, self-efficacy, self-regulation, and self-compassion in sustaining patient engagement and healing at home. The applicability of the therapeutic home environment as an adjunct is illustrated in the case of chronic migraine, a debilitating neurological condition commonly associated with comorbidities. Current challenges in achieving migraine freedom with FDA-approved pharmacotherapies, neuromodulation devices, and digital health technologies are underscored by the high prevalence of refractory, chronic, episodic, and pediatric migraine. Perspectives on developing a personalized, multimodal cure for migraine are illustrated through a hypothetical drug + digital combination therapy comprising anti-CGRP drugs and an AI-powered digital health platform that promotes daily self-care practices within the therapeutic home environments. In conclusion, achieving sustained freedom from high-morbidity conditions requires end-to-end care ecosystems that integrate pharmacological, cognitive, behavioral, and environmental interventions into real-world settings. Full article

Soil electrical resistivity (SER) is widely used as an indirect indicator of soil physical, chemical, and hydrological properties and plays an important role in applications such as grounding system design, geotechnical site characterization, agricultural soil monitoring, and environmental contamination assessment. However, SER is strongly influenced by environmental variables including soil moisture content, temperature, salinity, and soil texture, which makes accurate prediction challenging under heterogeneous field conditions. A systematic review was conducted following the PRISMA 2020 protocol using the Scopus database to identify peer-reviewed studies published between 2018 and 2026 related to predictive models of soil electrical resistivity based on environmental parameters. After applying defined inclusion and exclusion criteria, a set of relevant studies was selected for qualitative and comparative analysis. The reviewed studies consistently identify soil moisture content as the most frequently reported influential factor affecting SER, followed by temperature, salinity, and soil texture. This observation reflects the predominant focus of the analyzed literature within the selected time frame rather than a definitive representation of all controlling physical processes. Similarly, the reviewed literature suggests that empirical and statistical models remain valuable due to their simplicity and interpretability, whereas machine learning approaches such as artificial neural networks, support vector regression, and ensemble methods are often reported to achieve higher predictive accuracy in complex soil environments. The predictive SER modeling represents a rapidly evolving research field, and future work should focus on hybrid physics-informed machine learning models, the development of standardized datasets, and the integration of predictive algorithms with emerging sensing technologies and IoT-based monitoring systems. Full article

Global decarbonization and the rapid growth of distributed energy resources increase the need for information-centric mechanisms that can support secure, scalable, cross-border coordination under heterogeneous technical and regulatory conditions. This paper proposes a Global Virtual Prosumer (GVP) framework that integrates IoT sensing, multi-agent coordination, and permissioned blockchain smart contracts to operationalize cross-border energy services as auditable service commitments rather than physical power exchange. Building on prior work that validated MAS-based power management and blockchain-secured operation within individual Virtual Prosumers, the present contribution lies in the cross-border coordination layer and its associated contractual and evaluation mechanisms, not in the constituent technologies themselves. A layered IoT–AI–blockchain architecture is introduced, where off-chain optimization produces allocations and admissibility indicators and on-chain contracts enforce identity, feasibility guards, delegation and partner-assignment rules, oracle verification, and settlement time compliance outcomes. The contractual lifecycle is formalized through four smart-contract algorithms covering trade registration, conditional delegation, cooperative fulfillment, and cross-border settlement with explicit failure semantics and event-based audit trails. The framework is evaluated on a global case study with seven Virtual Prosumers and quantified using contract-centric KPIs that capture registration time rejections, settlement success versus non-compliance, oracle-driven failure attribution, and full lifecycle traceability. The results demonstrate internal consistency of the proposed lifecycle and the practical value of KPI-driven accountability for cross-border energy service coordination. At the same time, the evaluation is based on synthetic parameterization and an emulated contract environment; realistic deployment constraints—including consensus latency, cross-region communication reliability, and regulatory overlap—are discussed as explicit limitations and directions for future empirical validation. Full article

The global energy transition and the implementation of carbon capture, utilization, and storage (CCUS) strategies require energy-efficient and scalable CO₂ separation technologies. Mixed-matrix membranes (MMMs), combining polymer matrices with functional inorganic or hybrid nanofillers, have emerged as advanced separation platforms capable of surpassing the conventional permeability–selectivity trade-off observed in neat polymer membranes. This review critically evaluates recent developments in modern hybrid membranes for CO₂ separation from synthetic and industrial gas mixtures, including CO₂/N₂ (flue gas), CO₂/CH₄ (natural gas and biogas upgrading), and syngas systems. Particular emphasis is placed on MMMs incorporating covalent organic frameworks (COFs), metal–organic frameworks (MOFs), graphene oxide (GO), MXenes, transition metal dichalcogenides (TMDs), carbon nanotubes (CNTs), g-C₃N₄, layered double hydroxides (LDH), zeolites, metal oxides, and magnetic nanoparticles. Reported performance ranges include CO₂ permeability (P_CO2) typically between 100 and 800 Barrer, CO₂/N₂ selectivity up to 319, and CO₂/CH₄ selectivity up to 249, depending on filler chemistry, loading, and interfacial compatibility. The mechanisms governing gas transport—molecular sieving, selective adsorption, facilitated transport, and diffusion-pathway engineering—are systematically discussed. Key challenges addressed include filler dispersion, polymer–filler interfacial defects, physical aging, moisture sensitivity, oxidation (particularly in MXenes), and scalability toward industrial membrane modules. Future perspectives focus on sub-nanometer pore engineering, surface functionalization to enhance CO₂ affinity, controlled alignment of 2D nanosheets to promote directional transport, multifunctional core–shell and hollow structures, and the integration of computational modeling and machine learning for accelerated material design. Modern hybrid MMMs are identified as strategically important materials enabling high-efficiency CO₂ separation processes aligned with decarbonization and energy transition objectives. Full article

Flexible electrolyte-gated synaptic field-effect transistors (EGFETs) have emerged as a promising platform for neuromorphic visual systems, owing to their low-voltage operation, diverse synaptic plasticity, and exceptional mechanical flexibility. In particular, gel-based electrolytes, including hydrogels and ion gels, play a pivotal role as functional gate dielectrics, enabling efficient ion transport and strong ion–electron coupling through electric double-layer (EDL) formation. By leveraging these unique properties at the semiconductor/gel interface, EGFETs can effectively emulate essential biological synaptic behaviors, including short-term and long-term plasticity under optical stimulation. The inherent compatibility of EGFETs with a broad range of semiconductor channels, gel electrolytes, and flexible substrates enables the development of wearable and conformable neuromorphic platforms that seamlessly integrate sensing, memory, and signal processing within a single device architecture. Recent advances in gel material engineering, such as polymer network design, ionic modulation, and nanofiller incorporation, have significantly improved ion transport dynamics, interfacial stability, and device performance. Despite remaining challenges related to ion migration stability, multi-physical field coupling, and large-area device uniformity, these developments have substantially advanced the practical potential of gel-based systems. This review provides a comprehensive overview of the operating mechanisms, gel-based material systems, synaptic functionalities, mechanical reliability, and future prospects of flexible electrolyte-gated visual synapses, highlighting their considerable potential for next-generation intelligent perception and artificial vision technologies. Full article

The rapid inspection of urban road hazards, such as subsurface voids and pipeline damage, demands high efficiency and precision in detection technology. Conventional Ground Penetrating Radar (GPR) systems often face limitations in urban environments, including slow survey speeds, poor channel scalability, and the trade-off between shallow resolution and deep penetration. The proposed system integrates a dual-band antenna array (200 MHz and 400 MHz) to resolve the classical resolution–penetration trade-off, simultaneously capturing high-resolution shallow data and achieving deep subsurface penetration in a single pass. To overcome the sampling rate bottleneck inherent in low-cost microcontrollers, a custom Time-Division Step Multiplexing (TDSM) protocol extends the equivalent sampling period to 0.38 µs across 24 parallel channels while maintaining a 200 kHz pulse repetition rate—enabling real-time data streaming at vehicle speeds up to 70 km/h with 5 cm trace spacing. This capability directly addresses the critical challenge of traffic disruption on urban arterials caused by conventional slow-speed GPR surveys. Complementing this, a master-slave FPGA-MCU hierarchical architecture provides seamless channel scalability from 24 to 36 channels, adapting to diverse swath width requirements without hardware redesign. Laboratory physics model experiments demonstrate a penetration depth exceeding 3 m after convolutional sparse fusion of the dual-band data, covering the typical burial depth of urban utilities. This study provides a deployable high-resolution underground detection solution for rapid urban infrastructure surveys and emergency disease detection by breaking the traditional constraints of channel number, sampling rate, and detection speed, significantly reducing interference with urban main traffic. Full article

Three-dimensional integrated circuit (3D IC) packaging and heterogeneous integration have emerged as central pillars of contemporary semiconductor scaling. Yet, the multi-physics coupling inherent to stacked architectures manifesting as thermal hot spots, warpage-induced stresses, and interconnect aging demands monitoring and control capabilities that surpass traditional offline metrology. Although Digital Twin (DT) technology provides a principled route to real-time reliability management, the existing literature remains fragmented and frequently blurs the distinction between static multi-physics simulation workflows and truly dynamic, closed-loop twins. This critical review addresses these deficiencies through three main contributions. First, we clarify the Digital Twin hierarchy to resolve terminological ambiguity between digital models, shadows, and twins. Second, we synthesize three foundational enabling technologies. We examine physics-based modeling, emphasizing the shift from finite-element analysis (FEA) to real-time surrogates. We analyze data-driven paradigms, highlighting virtual metrology (VM) for inferring latent metrics. Finally, we explore in situ sensing, which serves as the “nervous system” coupling the physical stack to its virtual counterpart. Third, beyond a descriptive survey, we outline a possible hybrid DT architecture that leverages physics-informed machine learning (e.g., PINNs) to help reconcile data scarcity with latency constraints. Finally, we outline a standards-aligned roadmap incorporating IEEE 1451 and UCIe protocols to support the transition from passive digital shadows toward more adaptive and fully coupled Digital Twin frameworks for 3D IC manufacturing and field operation. Full article

Decarbonising greenhouse food production requires improvements in thermal management, energy efficiency, and system integration. Greenhouse energy demand is shaped by coupled heat and mass transfer processes, particularly envelope performance, ventilation, and latent heat associated with humidity control. This article synthesises recent advances in greenhouse microclimate control with emphasis on heat transfer, low-carbon heating and cooling, thermal storage, renewable and waste heat integration, and advanced modelling and control approaches. The review shows that humidity control and latent load management are primary drivers of winter energy use, as moisture removal through ventilation and dehumidification directly increases the sensible heating required to maintain indoor temperature setpoints. When assessed using realistic psychrometric relationships, ventilation and dehumidification can dominate peak heating demand and seasonal consumption. The performance of heat pumps, storage systems, semi-closed greenhouse concepts, and renewable heat pathways depends on how thermal loads are defined, how system boundaries are set, and how technologies are integrated in operation. Digital twins, predictive control, and hybrid physics-data models are increasingly used to manage variability in weather, energy prices, and infrastructure constraints. Greenhouse decarbonisation cannot be treated as a simple substitution of energy sources. System performance depends on coordinated design and operation, including heat recovery, moisture removal, and integration of supply technologies. Semi-closed and heat recovery-based configurations can reduce the ventilation–heating penalty and lower primary energy demand compared with vent-to-dry approaches. Long-term market projections suggest that the commercial greenhouse sector could expand substantially by 2050 under plausible growth scenarios, reflecting increased capital investment rather than a proportional rise in global food output. Net-zero greenhouse production is achievable through combined improvements in thermal management, electrification, and renewable energy integration. However, large-scale deployment depends on consistent modelling assumptions, credible economic assessment, and alignment with heat and CO₂ supply infrastructure. The transition is therefore shaped by system integration and planning as much as by individual technologies. Full article

With the deployment and application of the Fifth-Generation (5G) mobile communication technologies and the ongoing research and development of the Sixth-Generation (6G) mobile communication technologies, the space–air–ground–sea integrated network has become the core development vision for future communications. As aerial nodes, Unmanned Aerial Vehicles (UAVs) can be applied in a wide range of scenarios, including emergency rescue, surveying and mapping, environmental monitoring, and communication coverage enhancement. In terms of communication coverage enhancement, the space–air–ground integrated network, with UAVs as a key component, can provide seamless communication coverage for the full-domain three-dimensional space such as remote areas, deserts, and oceans. Benefiting from advantages such as low cost and high flexibility, UAVs have become a critical research focus, and the one-hop Base Station (BS)–relay UAV–slave UAV architecture for communication coverage enhancement has emerged as an important development direction. However, the high mobility and wide coverage characteristics of UAVs also pose significant synchronization challenges. Aiming at the uplink synchronization problem on the sidelink between slave UAVs and the relay UAV, a two-step random-access scheme based on Asynchronous Non-Orthogonal Multiple Access (A-NOMA) is designed to mitigate the Doppler Frequency Offset (DFO), improve access efficiency, reduce resource consumption, and accommodate the asynchrony among different users. This scheme leverages the existing preamble sequences of the Physical Random Access Channel (PRACH) and realizes DFO estimation in combination with the pairing index. On this basis, a Successive Interference Cancellation (SIC) algorithm based on DFO and phase compensation is designed to complete the demodulation of user data. For the downlink synchronization problem on the sidelink between slave UAVs and the relay UAV, the frequency offset estimation performance is improved by redesigning the resource allocation scheme of the Sidelink Synchronization Signal Block (S-SSB). Meanwhile, considering the energy constraint of UAVs, a downsampling-based detection scheme is designed to reduce UAV power consumption, and a full-link algorithm is developed to support the practical implementation of the proposed scheme. Full article

Background/Objectives: Magnetic nanoparticles have emerged as powerful tools for biomedical imaging, targeted drug delivery, and hyperthermia therapy. Magnetic particle imaging (MPI) is among the most promising technologies built around its properties: a radiation-free, quantitative tomographic modality that detects superparamagnetic iron oxide nanoparticles (SPIONs) directly against a biologically silent background. This review synthesizes MPI’s physical principles, nanoparticle design strategies, and preclinical applications within the broader landscape of magnetic material engineering for biomedical use. Methods: A systematic review was conducted covering MPI signal generation and image reconstruction, nanoparticle core synthesis and surface coating approaches, and preclinical applications, spanning cell tracking, oncological imaging, vascular perfusion, neuroimaging, and MPI-guided theranostics. Studies were selected to provide quantitative benchmarks and direct comparisons with competing modalities where available. Results: MPI delivers signal-to-background ratios above 1000:1, iron-mass linearity at R² ≥ 0.99, regardless of tissue depth, and acquisition rates up to 46 volumes per second. Tracer architecture—encompassing single-core particles, multicore nanoflowers, and stimuli-responsive cluster designs—is the primary determinant of sensitivity, environmental robustness, and theranostic capability. Preclinical results include detection of cell populations in the low thousands, earlier ischaemia identification than diffusion-weighted MRI, real-time drug release quantification, and spatially confined tumour hyperthermia. Three translational bottlenecks are identified: the absence of a clinically approved tracer with optimal relaxation dynamics, hardware performance losses when scaling to human-bore systems, and overestimation of passive tumour accumulation in murine models. Conclusions: MPI illustrates how progress in magnetic material design directly expands clinical imaging and theranostic possibilities. Successful translation will require indication-driven, interdisciplinary development that integrates materials science, scanner engineering, and regulatory strategy in parallel. Full article

Fine particulate matter PM_2.5 continues to pose a critical public health risk in Northern Thailand, particularly in Chiang Mai, where traditional filtration methods often face limitations in cost and efficiency for large-scale applications. This study introduces a novel “Evaporator Condensation Growth Particle Scrubber (ECGP)” designed to enhance the collection efficiency of sub-micron particles by enlarging their physical size through a pressure-driven growth mechanism. The ECGP system utilizes synergistic effects between solid nuclei, high relative humidity, and mechanical pressure modulation. The ECGP system integrates solid nuclei, ~95% relative humidity and mechanical pressure modulation within a single chamber. Using incense smoke as a PM surrogate, the process utilizes controlled adiabatic cycles to induce stable heterogeneous condensation. The results indicate that the integrated process effectively shifts particle size distribution, reducing the PM_2.5/PM₁₀ mass ratio from 1.00 to 0.83. This indicates that approximately 17.5% (with a standard deviation < 1% across 10 trials, p < 0.05) of the fine mass successfully transitioned into the larger, more filterable PM₁₀ fraction and exhibited high physical stability and resistance to re-evaporation, effectively overcoming the low-efficiency threshold (typically <10%) of standard mechanical scrubbers and cyclones for sub-micron dust. This study concludes that ECGP technology offers a promising, cost-effective alternative for improving indoor air quality in large public infrastructures by leveraging particle inertia for enhanced removal, providing a scalable solution to the persistent smog crisis. Full article

Surface Acoustic Wave (SAW) technology, long central to analog signal processing and RF filtering, is undergoing a major renewal. Driven by advances that decouple SAWs from traditional piezoelectric materials and fixed-function devices, the field is gaining unprecedented control over acoustic, optical, and electronic interactions at the micro and nanoscale. This review synthesizes these developments across four fronts: new physical mechanisms for SAW manipulation, emerging material platforms, ranging from thin films to 2D systems, along with reconfigurable device architectures and circuits, and the expanding landscape of applications they enable. Optical methods are reshaping how SAWs are generated and controlled, bypassing the limits of conventional electromechanical coupling. Coherent optical excitation of high-Q SAW cavities via Brillouin-like optomechanical interactions now grants access to modes in non-piezoelectric substrates such as diamond and silicon, while on-chip SAW excitation in photonic waveguides through backward stimulated Brillouin scattering opens new integrated sensing routes. In parallel, magneto-acoustic experiments have revealed nonreciprocal SAW diffraction from resonant scattering in magnetoelastic gratings. On the device side, ZnO thin-film transistors integrated on LiNbO₃ exploit acoustoelectric coupling to realize voltage-tunable phase shifters; UHF Z-shaped delay lines achieve high sensitivity in a compact footprint; and parametric synthesis of wideband, multi-stage lattice filters targets 5G-class performance. Atomistic simulations show that SAW propagation in 2D MXene films can be engineered via surface terminations, while aerosol jet printing and SAW-assisted particle patterning provide agile, cleanroom-light fabrication of microfluidic and magnetic components. These advances enable applications ranging from hybrid quantum systems and quantum links to lab-on-a-chip particle control, SBS-based and UHF sensing, reconfigurable RF front-ends, and soft robotic actuators based on patterned magnetic composites. At the same time, optical techniques offer non-contact probes of dissipation, and MXenes and other emerging materials open new regimes of acoustic control. Conclusively, they are transforming SAW technology into a versatile, programmable platform for mediating complex interactions in next-generation electronic, photonic, and quantum systems. Full article

In the era of highly integrated circuits, continuous miniaturization has significantly increased routing complexity, thereby directly impacting circuit performance. As process scaling advances and the number of on-chip metal layers increases, conventional standard cell libraries face limitations that cause severe routing bottlenecks. To overcome these limitations, this paper proposes a dual-component approach. First, we introduce a novel standard cell structure that improves routing flexibility by expanding the degrees of freedom for pin access, particularly in highly congested regions. Second, we present a physical design methodology specifically designed to ensure seamless integration with existing electronic design automation (EDA) tools, allowing new cells to be effectively placed and routed without major modifications to current flows. The proposed approach was validated using the open-source ASAP7 process design kit (PDK). Experimental results confirm significant reductions in via count and total wirelength, leading to improved routability, reduced power consumption, and enhanced performance. These findings demonstrate that combining the new cell architecture with a tailored design methodology provides a practical alternative to conventional solutions, enabling more efficient and scalable circuit designs for future technology nodes. Full article

With the rapid advancement in Generative Artificial Intelligence (GenAI), AI-generated content (AIGC) lacking human cognitive oversight is increasingly permeating open web environments and academic communication systems. This study integrates longitudinal retraction data (Retraction Watch Database, 1990–2026), web-scale analyses of AI-content penetration (Common Crawl, 2013–2026), and bibliometric mapping of governance scholarship (Web of Science Core Collection, Scopus, Google Scholar, 2020–2026) to diagnose the cross-level misalignment between synthetic-content diffusion, AI-related misconduct pressure, and governance attention. On this basis, it proposes a Normalized Coverage Index (NCI) to measure the relative relationship between scholarly attention to AI-related academic misconduct governance and the level of misconduct pressure observed through retraction data across disciplines. The results reveal pronounced asymmetries at the disciplinary level. Fields such as chemistry (0.04), physics, mathematics & statistics (0.11), and life sciences & biology (0.34) exhibit clear governance gaps, whereas Education shows a comparatively excessive level of attention (NCI = 29.26). Since 2022, AIGC has expanded rapidly across open web corpora, accompanied by a sharp rise in AI-related retractions, which also exhibit a longer detection lag than traditional forms of misconduct (2.77 years vs. 1.91 years). Although the volume of academic governance-related research has grown rapidly, its proportion within the broader body of AI-related research has declined, suggesting that scholarly attention to governance has not kept pace with technological diffusion. Consequently, a structural misalignment in governance—closely tied to the allocation of attention—has emerged within the academic system in the era of GenAI. This misalignment may pose potential risks to the robustness of the knowledge production system. Addressing it requires rebuilding epistemic infrastructure through provenance transparency, auditable workflows, and governance-aware seed corpora aligned with empirically concentrated risks. Full article

The evolution toward sixth-generation (6G) networks envisions humans as active nodes within a fully interconnected digital ecosystem, supported by data collected from in-body and on-body sensors. Since many of these devices are not equipped to connect directly to 6G networks, Wireless Body Area Networks (WBANs) serve as an essential intermediate layer. However, conventional radio-frequency technologies face limitations in terms of energy efficiency, security, and data integrity, motivating the adoption of lightweight security mechanisms. Physical Layer Security (PLS), and in particular Physical Key Extraction (PKE), offers a promising solution by enabling legitimate devices to derive shared cryptographic keys from the reciprocal properties of the communication channel. Galvanic coupling (GC) communication has recently emerged as an on-body transmission technology alternative to radio-frequency (RF), which exploits low-power electrical signals propagating through biological tissue. Building on prior feasibility studies, this work proposes a PKE framework tailored to GC channels, integrating a lightweight key reconciliation method, based on Hamming (7,4) error-correction codes, and evaluating system performance through dedicated reliability and security Key Performance Indicators (KPIs). Results reveal a trade-off shaped by electrode placement and channel quantization parameters. Among the ones tested, the optimal configuration is achieved with a 3 cm transverse inter-electrode spacing at both transmitter and receiver, and a 3 cm longitudinal separation between transmitter and receiver, by quantizing the channel impulse response with two quantization bits. While this work focuses on validating the method in controlled conditions in order to establish a reliable study framework, future developments will focus on enhanced reconciliation, privacy amplification, and analysis of the GC channel considering physiological and environmental variations. Full article