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23 pages, 12985 KB  
Article
Seven Decades of Aridity Transitions in China: Spatiotemporal Patterns and Contemporary Hydrological Responses
by Jiasen He, Haishan Niu, Lei Feng, Runkui Li, Afera Halefom, Yan He, Xianfeng Song and Zheng Duan
Remote Sens. 2026, 18(5), 749; https://doi.org/10.3390/rs18050749 - 1 Mar 2026
Viewed by 373
Abstract
Global warming profoundly affects hydrological processes and regional aridity. However, the shifts in the arid–humid transition zone and its relationship to divergent surface and subsurface hydrological responses remain not fully understood. This study investigates the spatiotemporal aridity changes in China using hydroclimate datasets [...] Read more.
Global warming profoundly affects hydrological processes and regional aridity. However, the shifts in the arid–humid transition zone and its relationship to divergent surface and subsurface hydrological responses remain not fully understood. This study investigates the spatiotemporal aridity changes in China using hydroclimate datasets (1950–2022) and examines associated hydrological responses via remote sensing (RS) since the early 2000s. The results reveal that: (1) a pronounced ~32-year oscillatory pattern governs both the expansion and contraction of drylands and non-drylands, with China currently in a wetting phase; (2) a distinct climatic transitional zone is identified, and a distinct boundary emerges separating drylands and non-drylands, here referred to as China’s Arid–Humid Divide, reflecting the climatic equilibrium shaped by multiple monsoon systems and local topography; and (3) the nationwide expansion of surface water bodies, following the increase of groundwater storage in partial areas, was detected via recent RS data. These findings provide new insights into the mechanisms driving long-term aridity transitions and support climate adaptation and sustainable land management in China. Full article
(This article belongs to the Section Ecological Remote Sensing)
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17 pages, 1246 KB  
Article
A Floquet-Style Stability Analysis of the Disease-Free State in a Seasonal Hantavirus Model
by Asep K. Supriatna, Dwi Agustian, Maya Rayungsari, Hennie Husniah and Riana N. Pakpahan
Mathematics 2026, 14(4), 694; https://doi.org/10.3390/math14040694 - 16 Feb 2026
Viewed by 319
Abstract
In this study, we developed an SIR-like mathematical model of disease transmission dynamics. Hantavirus is a neglected tropical disease, and this paper presents a mathematical model of hantavirus transmission among rodents and its effect on the number of hantavirus-infected humans. We review an [...] Read more.
In this study, we developed an SIR-like mathematical model of disease transmission dynamics. Hantavirus is a neglected tropical disease, and this paper presents a mathematical model of hantavirus transmission among rodents and its effect on the number of hantavirus-infected humans. We review an existing SIR-SIR model of hantavirus transmission and analyze it in a standard mathematical epidemiology framework. The original SIR-SIR model is summarized, with emphasis on its structural assumptions, epidemiological interpretation, and analytical results, including the derivation of the basic reproduction number and the characterization of the stability of the disease-free and endemic equilibria. A critical evaluation of the original SIR-SIR model highlights several biological limitations of the baseline model, notably, the unrealistic assumption of homogeneous transmission and the absence of ecological seasonality. To address these gaps, an improved model incorporating periodic forcing in rodent recruitment and disease transmission is proposed. The use of sine and cosine functions introduces a biologically motivated phase shift between rodent recruitment and transmission, reflecting the fact that birth pulses and peak contact rates rarely occur simultaneously in natural rodent populations. The reproduction number for the extended system is constructed using a Floquet-style argument for DFE stability. A theorem connecting the stability of the DFE with the seasonal component is presented, resembling the well-known rule for non-seasonal hantavirus transmission but with more realistic assumptions. Numerical simulations demonstrate that seasonal variation can generate oscillatory outbreak patterns that more closely reflect empirical rodent population dynamics and human risk profiles. Overall, the results underscore the importance of ecological realism in zoonotic disease modeling and provide a foundation for more accurate prediction and control of the disease, especially in NTD elimination programs. Full article
(This article belongs to the Section E3: Mathematical Biology)
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22 pages, 8986 KB  
Article
Asymmetry- and Viscosity-Regulated Atomization of Laminar Impinging Microjets: Morphology Map, Modal Dynamics, and Droplet Statistics
by Xiaoyu Tan, Guohui Cai, Bo Wang and Xiaodong Chen
Micromachines 2026, 17(2), 221; https://doi.org/10.3390/mi17020221 - 7 Feb 2026
Viewed by 378
Abstract
Despite decades of studies on symmetric impinging-jet atomization, the combined role of controlled pre-impingement asymmetry and viscosity in setting the instability pathways and droplet statistics of laminar microjets remains insufficiently quantified. The effects of pre-impingement jet-length difference and liquid viscosity on the flow [...] Read more.
Despite decades of studies on symmetric impinging-jet atomization, the combined role of controlled pre-impingement asymmetry and viscosity in setting the instability pathways and droplet statistics of laminar microjets remains insufficiently quantified. The effects of pre-impingement jet-length difference and liquid viscosity on the flow morphologies, instability dynamics, and atomization behavior of laminar impinging microjets are investigated experimentally using high-speed imaging. By systematically varying the jet-length asymmetry and viscosity over a range of Weber numbers, the evolution of liquid-sheet motion and breakup is resolved from synchronized front- and side-view observations. Specifically, the scientific objective of this work is to elucidate how pre-impingement jet-length asymmetry and liquid viscosity jointly regulate the dynamical behavior of laminar impinging microjets, with particular emphasis on regime transitions of liquid-sheet morphologies, the coupling between upper-sheet oscillations and rim instabilities revealed by synchronized multi-view imaging and POD-based frequency analysis and the resulting droplet-size statistics. These aspects address physical questions that have not been systematically resolved in classical impinging-jet studies, which predominantly focus on symmetric configurations or performance-oriented atomization. With increasing Weber number, the flow undergoes a sequence of regime transitions, including merged-jet, liquid-chain, wavy-rim, fishbone, closed-rim, open-rim, and arc-shaped atomization states. The presence and extent of the closed-rim regime depend sensitively on both jet-length asymmetry and liquid viscosity. Increasing jet-length difference accelerates transitions between these regimes, whereas increasing liquid viscosity stabilizes the liquid sheet and shifts the onset of unsteady breakup to higher Weber numbers. Proper orthogonal decomposition is applied to time-resolved image sequences to extract dominant oscillatory modes and their characteristic frequencies. Within the fishbone regime, the oscillation frequency of rim deformation either coincides with that of the upper region of the liquid sheet or appears as its subharmonic, indicating period-doubling behavior under specific combinations of Weber number and jet-length asymmetry. These frequency characteristics govern the spatiotemporal organization of ligament formation and detachment along the sheet rim. In the arc-shaped atomization regime, droplet-size distributions follow a log-normal form, and at sufficiently high Weber numbers, the mean droplet diameter shows only a weak dependence on jet-length asymmetry. These findings provide microscale-regime guidance for tunable droplet formation in open microfluidic jetting and related small-scale multiphase flows. The innovation of this study lies in the systematic use of synchronized multi-view imaging combined with POD-based frequency analysis and droplet statistics to directly connect liquid-sheet oscillations, rim instability dynamics, and breakup organization under controlled geometric asymmetry and viscosity variations. This approach enables a unified physical interpretation of regime transitions and instability mechanisms that cannot be resolved from single-view observations or morphology-based classification alone. Full article
(This article belongs to the Topic Fluid Mechanics, 2nd Edition)
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20 pages, 5989 KB  
Article
UV and Visible Radiation Characteristics of Thermoacoustic Instabilities in an Ammonia–Methane Premixed Swirl-Stabilized Combustor
by Junhui Ma, Xianglan Fu, Dongqi Chen, Le Chang, Lingxue Wang, Yingchen Shi, Haocheng Wen and Bing Wang
Energies 2026, 19(3), 759; https://doi.org/10.3390/en19030759 - 31 Jan 2026
Viewed by 472
Abstract
Ammonia (NH3) is a promising carbon-free energy carrier for low-carbon power generation. However, in turbulent ammonia–methane (NH3-CH4) premixed swirling flames, operating at lean conditions to limit NOX, emissions can trigger strong thermoacoustic oscillations. This study [...] Read more.
Ammonia (NH3) is a promising carbon-free energy carrier for low-carbon power generation. However, in turbulent ammonia–methane (NH3-CH4) premixed swirling flames, operating at lean conditions to limit NOX, emissions can trigger strong thermoacoustic oscillations. This study investigates thermoacoustic oscillatory instability in an NH3-CH4 swirl-stabilized combustor using the chemiluminescence of CH*, OH*, and NH* over a wide range of ammonia fuel fraction (XNH3). Combined spectral measurements and 2D chemiluminescence imaging are employed to obtain the global emission characteristics and spatial distributions of OH* and NH* in the UV band and CH* in the visible band. A custom-designed intensified CMOS (ICMOS) camera based on a high-gain UV–visible image intensifier with direct coupling is developed to enable sensitive OH* and NH* imaging (gain > 104). Frequency analysis of continuous CH* imaging, together with morphology-based principal component analysis and k-means clustering of 46 image features, shows that oscillatory combustion occurs for XNH3 < 0.40, whereas XNH3 ≥ 0.40 leads to multimode, stable combustion. As XNH3 increases, OH* and NH* fields progressively decouple from CH*, becoming more elongated and shifting downstream. These results demonstrate that UV radical chemiluminescence provides indispensable information on NH3 reaction zones and should be combined with CH* diagnostics for reliable thermoacoustic analysis and control in practical NH3-fueled combustion systems. Full article
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17 pages, 7284 KB  
Article
Dynamics and Solution Behavior of the Variable-Order Fractional Newton–Leipnik System
by Rania Saadeh, Nidal E. Taha, Mohamed Hafez, Ghozail Sh. Al-Mutairi and Manahil A. M. Ashmaig
Mathematics 2026, 14(2), 312; https://doi.org/10.3390/math14020312 - 16 Jan 2026
Viewed by 463
Abstract
This paper considers the solution behavior and dynamical properties of the variable-order fractional Newton–Leipnik system defined via Liouville–Caputo derivatives of variable order. In contrast to integer-order models, the presence of variable-order fractional operators in the Newton–Leipnik structure enriches the model by providing memory-dependent [...] Read more.
This paper considers the solution behavior and dynamical properties of the variable-order fractional Newton–Leipnik system defined via Liouville–Caputo derivatives of variable order. In contrast to integer-order models, the presence of variable-order fractional operators in the Newton–Leipnik structure enriches the model by providing memory-dependent effects that vary with time; hence, it is capable of a broader and more flexible range of nonlinear responses. Numerical simulations have been conducted to study how different order functions influence the trajectory and qualitative dynamics: clear transitions in oscillatory patterns have been identified by phase portraits, time-series profiles, and three-dimensional state evolution. The work goes further by considering the development of bifurcations and chaotic regimes and stability shifts and confirms the occurrence of several phenomena unattainable in fixed-order and/or integer-order formulations. Analysis of Lyapunov exponents confirms strong sensitivity to the initial conditions and further details how the memory effects either reinforce or prevent chaotic oscillations according to the type of order function. The results, in fact, show that the variable-order fractional Newton–Leipnik framework allows for more expressive and realistic modeling of complex nonlinear phenomena and points out the crucial role played by evolving memory in controlling how the system moves between periodic, quasi-periodic, and chaotic states. Full article
(This article belongs to the Section C1: Difference and Differential Equations)
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20 pages, 4131 KB  
Article
Graph Analysis of Age-Related Changes in Resting-State Functional Connectivity Measured with fNIRS
by Víctor Sánchez, Sergio Novi, Alex C. Carvalho, Andres Quiroga, Rodrigo Menezes Forti, Fernando Cendes, Clarissa Lin Yasuda and Rickson C. Mesquita
J. Ageing Longev. 2026, 6(1), 11; https://doi.org/10.3390/jal6010011 - 15 Jan 2026
Viewed by 634
Abstract
Resting-state functional connectivity (rsFC) provides insight into the intrinsic organization of brain networks and is increasingly recognized as a sensitive marker of age-related neural changes. Functional near-infrared spectroscopy (fNIRS) offers a portable and cost-effective approach to measuring rsFC, including in naturalistic settings. However, [...] Read more.
Resting-state functional connectivity (rsFC) provides insight into the intrinsic organization of brain networks and is increasingly recognized as a sensitive marker of age-related neural changes. Functional near-infrared spectroscopy (fNIRS) offers a portable and cost-effective approach to measuring rsFC, including in naturalistic settings. However, its sensitivity to age-related alterations in network topology remains poorly characterized. Here, we applied graph-based analysis to resting-state fNIRS data from 57 healthy participants, including 26 young adults (YA, 18–30 years) and 31 older adults (OA, 50–77 years). We observed that older adults exhibited a marked attenuation of low-frequency oscillation (LFO) power across all hemoglobin contrasts, corresponding to a 5–6-fold reduction in spectral power. In addition, network analysis revealed altered topological organization under matched sparsity conditions, characterized by reduced degree heterogeneity and increased segregation in older adults, with the strongest differences observed in the default mode (DMN), auditory, and frontoparietal control (FPC) networks. Network visualizations further indicated a shift toward more right-lateralized and posterior hub organization in older adults. Together, the coexistence of reduced oscillatory power and increased connectivity suggests that fNIRS-derived rsFC reflects combined neural and non-neural hemodynamic influences, including increased coherence arising from age-related vascular and systemic physiological processes. Overall, our findings demonstrate that fNIRS is sensitive to age-related changes in large-scale hemodynamic network organization. At the same time, sensitivity to non-neural hemodynamics highlights the need for cautious interpretation, but it may provide complementary, clinically relevant signatures of aging-related changes. Full article
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32 pages, 10354 KB  
Article
Advanced Energy Management and Dynamic Stability Assessment of a Utility-Scale Grid-Connected Hybrid PV–PSH–BES System
by Sharaf K. Magableh, Mohammad Adnan Magableh, Oraib M. Dawaghreh and Caisheng Wang
Electronics 2026, 15(2), 384; https://doi.org/10.3390/electronics15020384 - 15 Jan 2026
Viewed by 463
Abstract
Despite the growing adoption of hybrid energy systems integrating solar photovoltaic (PV), pumped storage hydropower (PSH), and battery energy storage (BES), comprehensive studies on their dynamic stability and interaction mechanisms remain limited, particularly under weak grid conditions. Due to the high impedance of [...] Read more.
Despite the growing adoption of hybrid energy systems integrating solar photovoltaic (PV), pumped storage hydropower (PSH), and battery energy storage (BES), comprehensive studies on their dynamic stability and interaction mechanisms remain limited, particularly under weak grid conditions. Due to the high impedance of weak grids, ensuring stability across varied operating scenarios is crucial for advancing grid resilience and energy reliability. This paper addresses these research gaps by examining the interaction dynamics between PV, PSH, and BES on the DC side and the utility grid on the AC side. The study identifies operating-region-dependent instability mechanisms arising from negative incremental resistance behavior and weak grid interactions and proposes a virtual-impedance-based active damping control strategy to suppress poorly damped oscillatory modes. The proposed controller effectively reshapes the converter output impedance, shifts unstable eigenmodes into the left-half plane, and improves phase margins without requiring additional hardware components or introducing steady-state power losses. System stability is analytically assessed using root-locus, Bode, and Nyquist criteria within a developed small-signal state-space model, and further validated through large-signal real-time simulations on an OPAL-RT platform. The main contributions of this study are threefold: (i) a comprehensive stability analysis of a utility-scale grid-connected hybrid PV–PSH–BES system under weak grid conditions, (ii) identification of operating-region-dependent instability mechanisms associated with DC–link interactions, and (iii) development and real-time validation of a practical virtual-impedance-based active damping strategy for enhancing system stability and grid integration reliability. Full article
(This article belongs to the Special Issue Advances in Power Electronics Converters for Modern Power Systems)
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28 pages, 16312 KB  
Article
PS-InSAR Monitoring Integrated with a Bayesian-Optimized CNN–LSTM for Predicting Surface Subsidence in Complex Mining Goafs Under a Symmetry Perspective
by Tianlong Su, Linxin Zhang, Xuzhao Yuan, Xiaoquan Li, Xuefeng Li, Xuxing Huang, Zheng Huang and Danhua Zhu
Symmetry 2025, 17(12), 2152; https://doi.org/10.3390/sym17122152 - 14 Dec 2025
Viewed by 732
Abstract
Mine-induced surface subsidence threatens infrastructure and can trigger cascading geohazards, so accurate and computationally efficient monitoring and forecasting are essential for early warning. We integrate Persistent Scatterer InSAR (PS-InSAR) time series with a Bayesian-optimized CNN–LSTM designed for spatiotemporal prediction. The CNN extracts spatial [...] Read more.
Mine-induced surface subsidence threatens infrastructure and can trigger cascading geohazards, so accurate and computationally efficient monitoring and forecasting are essential for early warning. We integrate Persistent Scatterer InSAR (PS-InSAR) time series with a Bayesian-optimized CNN–LSTM designed for spatiotemporal prediction. The CNN extracts spatial deformation patterns, the LSTM models temporal dependence, and Bayesian optimization selects the architecture, training hyperparameters, and the most informative exogenous drivers. Groundwater level and backfilling intensity are encoded as multichannel inputs. Endpoint anchoring with affine calibration aligns the historical series and the forward projections. PS-InSAR indicates a maximum subsidence rate of 85.6 mm yr−1, and the estimates are corroborated against nearby leveling benchmarks and FLAC3D simulations. Cross-site comparisons show acceleration followed by deceleration after backfilling and groundwater recovery, which is consistent with geological engineering conditions. A symmetry-aware preprocessing step exploits axial regularities of the deformation field through mirroring augmentation and documents symmetry-breaking hotspots linked to geological heterogeneity. These choices improve generalization to shifted and oscillatory patterns in both the spatial CNN and the temporal LSTM branches. Short-term forecasts from the BO–CNN–LSTM indicate subsequent stabilization with localized rebound, highlighting its practical value for operational planning and risk mitigation. The framework combines automated hyperparameter search with physically consistent objectives, reduces manual tuning, enhances reproducibility and generalizability, and provides a transferable quantitative workflow for forecasting mine-induced deformation in complex goaf systems. Full article
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11 pages, 1697 KB  
Article
The Effect of Additive and Multiplicative Cyclic Perturbations on Noise-Induced Tipping Dynamics
by Igor A. Khovanov and Natasha A. Khovanova
Entropy 2025, 27(12), 1255; https://doi.org/10.3390/e27121255 - 13 Dec 2025
Viewed by 542
Abstract
The dynamics of systems near tipping points attract considerable attention in the context of climate change, ecological regime shifts, disease spreading, and other complex systems undergoing transitions. In particular, the duration and cause of transitions between states remain subjects of ongoing debate. We [...] Read more.
The dynamics of systems near tipping points attract considerable attention in the context of climate change, ecological regime shifts, disease spreading, and other complex systems undergoing transitions. In particular, the duration and cause of transitions between states remain subjects of ongoing debate. We address these questions by applying the large-fluctuation framework to analyse noise-induced transitions in a widely studied tipping model describing dynamics near a fold bifurcation. As complex systems are typically not in equilibrium, we include cyclic perturbations representing, for example, diurnal variations, seasonal cycles, solar activity oscillations, and Milankovitch cycles in the climate system. We investigate how the frequency and type of cyclic perturbation influence noise-induced transitions between states by examining the fluctuational force. Two types of periodic perturbations, additive and multiplicative, representing B- and R-tipping, are considered. We show, first, that depending on the type of cyclic perturbation, the fluctuations need to be synchronised with different perturbation phases to induce the transition. Secondly, we demonstrate that the transition duration depends on the perturbation frequency: when the periodic perturbation is slower than the system’s relaxation rate, the transition occurs within a single oscillatory cycle, whereas high-frequency perturbations can significantly prolong the transition time. Full article
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26 pages, 6335 KB  
Article
Integration of Nonlinear Rheology and CFD Simulation to Elucidate the Influence of Saturated Oil on Soy Protein Concentrate Behavior During High-Moisture Extrusion
by Timilehin Martins Oyinloye, Chae-Jin Lee and Won Byong Yoon
Gels 2025, 11(12), 1003; https://doi.org/10.3390/gels11121003 - 12 Dec 2025
Cited by 1 | Viewed by 630
Abstract
This study investigated the influence of coconut oil concentration (0–2%) on the nonlinear rheological and thermal behavior of soy protein concentrate (SPC) mixtures and integrated these data into computational fluid dynamics (CFD) models to predict flow behavior during high-moisture extrusion. Temperature sweep tests [...] Read more.
This study investigated the influence of coconut oil concentration (0–2%) on the nonlinear rheological and thermal behavior of soy protein concentrate (SPC) mixtures and integrated these data into computational fluid dynamics (CFD) models to predict flow behavior during high-moisture extrusion. Temperature sweep tests revealed that increasing oil content elevated the onset and peak gelation temperatures from 64.13 to 70.21 °C and 70.29 to 76.08 °C, respectively, while decreasing gelation enthalpy from 4.05 J/g to 2.81 J/g. Large-amplitude oscillatory shear (LAOS) analysis showed a shift from strain-stiffening (e3/e1 > 0.15) behavior to strain-thinning (e3/e1 < 0.05) behavior with increasing oil, accompanied by enhanced shear-thinning behavior (v3/v1 < 0). Integrating these nonlinear parameters into the CFD simulations enhanced model accuracy relative to the SAOS-based approach, resulting in lower RMSE values (≤4.41 kPa for pressure and ≤0.11 mm/s for velocity) and enabling more realistic prediction of deformation and flow under extrusion-relevant conditions, a capability that conventional SAOS-based models could not achieve. Predicted outlet melt temperatures averaged 70.27 ± 1.55 °C, consistent with experimental results. The findings demonstrate that oil addition modulates protein network formation and flow resistance, and that nonlinear rheology-coupled CFD models enable reliable prediction of extrusion behavior. Overall, this study provides a novel rheology-driven modeling strategy for enhancing the design and optimization of oil-enriched plant-protein extrusion processes. Full article
(This article belongs to the Special Issue Recent Developments in Food Gels (3rd Edition))
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41 pages, 26216 KB  
Article
Spatiotemporal Heterogeneity and Multi-Scale Determinants of Human Mobility Pulses: The Case of Harbin City
by Xinyue Xu, Ming Sun and Qimeng Ren
Sustainability 2025, 17(23), 10514; https://doi.org/10.3390/su172310514 - 24 Nov 2025
Viewed by 541
Abstract
To enhance winter tourism competitiveness and address seasonal tourist flow pressures, this study adopts Harbin as a case study and introduces a metamodernist theoretical framework. This framework redefines the “population pulse” phenomenon as a structural oscillation involving periodic switching between the two poles [...] Read more.
To enhance winter tourism competitiveness and address seasonal tourist flow pressures, this study adopts Harbin as a case study and introduces a metamodernist theoretical framework. This framework redefines the “population pulse” phenomenon as a structural oscillation involving periodic switching between the two poles of global tourist consumption and local resident daily needs. By integrating multi-source spatiotemporal data, the study employs X-means clustering to identify population aggregation–dispersion patterns and combines the Geographical Detector and GWR model to construct a complete technical pathway ranging from global factor detection to local heterogeneity analysis. The findings reveal that (1) population activity in Harbin exhibits a “monocentric polarization” pattern during the peak season, which shifts to a “polycentric weak agglomeration” mode in the off-season, reflecting the seasonal oscillation of the city’s functional roles; (2) X-means clustering identifies three types of functional zones: transit-oriented areas on the urban periphery, commercial supporting service zones, and core commercial districts; (3) the Geographical Detector quantifies the independent explanatory power and interactive effects of various influencing factors, identifying the interaction between POI density and road network accessibility as having the strongest explanatory power regarding population aggregation; (4) GWR analysis reveals significant spatiotemporal heterogeneity in the effects of various built environment and socioeconomic driving factors. This study provides specific evidence and technical support for urban planning practices in Harbin and other similar cities, deepens the theoretical understanding of the “constitutive conditions” of urban vitality, and explores a post-paradigmatic research path in geographical methodology that can embrace complexity and analyze oscillatory behavior. Full article
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23 pages, 5447 KB  
Article
3D-Printed Alginate–Chitosan Hydrogel Loaded with Cannabidiol as a Platform for Drug Delivery: Design and Mechanistic Characterization
by Hernan Santiago Garzon, Camilo Alfonso-Rodríguez, João G. S. Souza, Lina J. Suárez and Daniel R. Suárez
J. Funct. Biomater. 2025, 16(11), 422; https://doi.org/10.3390/jfb16110422 - 12 Nov 2025
Cited by 1 | Viewed by 1656
Abstract
Alginate and chitosan (Ag/Cs) combined form an effective platform to develop biocompatible hydrogels with customizable properties for controlled drug release. Cannabidiol (CBD), a hydrophobic compound with anti-inflammatory and antibacterial effects, represents a powerful strategy to enhance their therapeutic performance. A/Cs hydrogels were produced [...] Read more.
Alginate and chitosan (Ag/Cs) combined form an effective platform to develop biocompatible hydrogels with customizable properties for controlled drug release. Cannabidiol (CBD), a hydrophobic compound with anti-inflammatory and antibacterial effects, represents a powerful strategy to enhance their therapeutic performance. A/Cs hydrogels were produced using the CELLINK® printer with 12 and 24 mg/mL of CBD. SEM and FTIR were assessed. Viscoelasticity was assessed using oscillatory rheology. Structural strength was evaluated via uniaxial compression. Swelling and absorption were measured gravimetrically under physiological conditions. CBD was successfully incorporated into the 3D-printed A/Cs hydrogel. Increasing the CBD concentration led to mechanical changes such as a dose-dependent decrease in G′ and a slight reduction in the linearity threshold (typically 10–30% from medium loads), while still maintaining G′ > G″. FTIR showed shifts in O–H/N–H and C=O, indicating hydrogen bonding without new reactive bands. Microscopic images revealed moderate pore compaction and increased tortuosity with dose. At higher CBD concentrations, the hydrogel resisted compression but could deform further before failure. Equilibrium swelling and absorption kinetics decreased with increasing dose, resulting in a reduced initial burst and lower water uptake capacity. The CBD-loaded hydrogel provides a mechanically suitable and molecularly stable platform for local drug release in the oral cavity. Full article
(This article belongs to the Special Issue Biomaterials and Bioengineering in Dentistry (2nd Edition))
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18 pages, 716 KB  
Article
Metacognitive Modulation of Cognitive-Emotional Dynamics Under Social-Evaluative Stress: An Integrated Behavioural–EEG Study
by Katia Rovelli, Angelica Daffinà and Michela Balconi
Appl. Sci. 2025, 15(19), 10678; https://doi.org/10.3390/app151910678 - 2 Oct 2025
Viewed by 1368
Abstract
Background/Objectives: Decision-making under socially evaluative stress engages a dynamic interplay between cognitive control, emotional appraisal, and motivational systems. Contemporary models of multi-level co-regulation posit that these systems operate in reciprocal modulation, redistributing processing resources to prioritise either rapid socio-emotional alignment or deliberate evaluation [...] Read more.
Background/Objectives: Decision-making under socially evaluative stress engages a dynamic interplay between cognitive control, emotional appraisal, and motivational systems. Contemporary models of multi-level co-regulation posit that these systems operate in reciprocal modulation, redistributing processing resources to prioritise either rapid socio-emotional alignment or deliberate evaluation depending on situational demands. Methods: Adopting a neurofunctional approach, a novel dual-task protocol combining the MetaCognition–Stress Convergence Paradigm (MSCP) and the Social Stress Test Neuro-Evaluation (SST-NeuroEval), a simulated social–evaluative speech task calibrated across progressive emotional intensities, was implemented. Twenty professionals from an HR consultancy firm participated in the study, with concurrent recording of frontal-temporoparietal electroencephalography (EEG) and bespoke psychometric indices: the MetaStress-Insight Index and the TimeSense Scale. Results: Findings revealed that decision contexts with higher socio-emotional salience elicited faster, emotionally guided choices (mean RT difference emotional vs. cognitive: −220 ms, p = 0.026), accompanied by oscillatory signatures (frontal delta: F(1,19) = 13.30, p = 0.002; gamma: F(3,57) = 14.93, p ≤ 0.001) consistent with intensified socio-emotional integration and contextual reconstruction. Under evaluative stress, oscillatory activity shifted across phases, reflecting the transition from anticipatory regulation to reactive engagement, in line with models of phase-dependent stress adaptation. Across paradigms, convergences emerged between decision orientation, subjective stress, and oscillatory patterns, supporting the view that cognitive–emotional regulation operates as a coordinated, multi-level system. Conclusions: These results underscore the importance of integrating behavioural, experiential, and neural indices to characterise how individuals adaptively regulate decision-making under socially evaluative stress and highlight the potential of dual-paradigm designs for advancing theory and application in cognitive–affective neuroscience. Full article
(This article belongs to the Special Issue Brain Functional Connectivity: Prediction, Dynamics, and Modeling)
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37 pages, 5162 KB  
Article
Fourier–Gegenbauer Integral Galerkin Method for Solving the Advection–Diffusion Equation with Periodic Boundary Conditions
by Kareem T. Elgindy
Computation 2025, 13(9), 219; https://doi.org/10.3390/computation13090219 - 9 Sep 2025
Viewed by 1225
Abstract
This study presents the Fourier–Gegenbauer integral Galerkin (FGIG) method, a new numerical framework that uniquely integrates Fourier series and Gegenbauer polynomials to solve the one-dimensional advection–diffusion (AD) equation with spatially symmetric periodic boundary conditions, achieving exponential convergence and reduced computational cost compared to [...] Read more.
This study presents the Fourier–Gegenbauer integral Galerkin (FGIG) method, a new numerical framework that uniquely integrates Fourier series and Gegenbauer polynomials to solve the one-dimensional advection–diffusion (AD) equation with spatially symmetric periodic boundary conditions, achieving exponential convergence and reduced computational cost compared to traditional methods. The FGIG method uniquely combines Fourier series for spatial periodicity and Gegenbauer polynomials for temporal integration within a Galerkin framework, resulting in highly accurate numerical and semi-analytical solutions. Unlike traditional approaches, this method eliminates the need for time-stepping procedures by reformulating the problem as a system of integral equations, reducing error accumulation over long-time simulations and improving computational efficiency. Key contributions include exponential convergence rates for smooth solutions, robustness under oscillatory conditions, and an inherently parallelizable structure, enabling scalable computation for large-scale problems. Additionally, the method introduces a barycentric formulation of the shifted Gegenbauer–Gauss (SGG) quadrature to ensure high accuracy and stability for relatively low Péclet numbers. This approach simplifies calculations of integrals, making the method faster and more reliable for diverse problems. Numerical experiments presented validate the method’s superior performance over traditional techniques, such as finite difference, finite element, and spline-based methods, achieving near-machine precision with significantly fewer mesh points. These results demonstrate its potential for extending to higher-dimensional problems and diverse applications in computational mathematics and engineering. The method’s fusion of spectral precision and integral reformulation marks a significant advancement in numerical PDE solvers, offering a scalable, high-fidelity alternative to conventional time-stepping techniques. Full article
(This article belongs to the Special Issue Advances in Computational Methods for Fluid Flow)
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38 pages, 6285 KB  
Article
Synergy Effect of Synthetic Wax and Tall Oil Amidopolyamines for Slowing Down the Aging Process of Bitumen
by Mateusz M. Iwański, Szymon Malinowski, Krzysztof Maciejewski and Grzegorz Mazurek
Materials 2025, 18(17), 4135; https://doi.org/10.3390/ma18174135 - 3 Sep 2025
Viewed by 1229
Abstract
Bitumen ages during production and in asphalt pavements, leading to structural issues and reduced durability of asphalt pavements. The alteration of bitumen’s viscoelastic properties, predominantly attributable to oxidation phenomena, is a hallmark of these processes. This study analyzed the use of a new [...] Read more.
Bitumen ages during production and in asphalt pavements, leading to structural issues and reduced durability of asphalt pavements. The alteration of bitumen’s viscoelastic properties, predominantly attributable to oxidation phenomena, is a hallmark of these processes. This study analyzed the use of a new generation of synthetic wax (SWLC), which was selected for its low carbon footprint, ability to reduce binder viscosity, and ability to enable the production of WMA. Tall oil amidopolyamines (TOAs), a renewable raw material-based adhesive and aging inhibitor, was also used in this study. It compensates for the unfavorable effect of stiffening the binder with synthetic wax. SWLC at concentrations of 1.0%, 1.5%, 2.0%, and 2.5% by mass in bitumen, in conjunction with TOAs at concentrations of 0.0%, 0.2%, 0.4%, and 0.6% by bitumen weight were tested at various concentrations. Short-term and long-term aging effects on penetration, softening point, and viscosity multiple creep and stress recovery tests (MSCR), oscillatory tests for the combined complex modulus |G*| and phase shift angle sin(δ) (DSR), and low-temperature characteristics Sm and mvalue (BBR) were analyzed. The chemical composition of the binders was then subjected to Fourier Infrared Spectroscopy (FTIR) analysis, which enabled the determination of carbonyl, sulfoxide, and aromaticity indexes. These results indicated that the additives used inhibit the oxidation and aromatization reactions of the bitumen components. The optimal SWLC and TOA content determined was 1.5% and 0.4% w/w, respectively. These additives reduce aging and positively affect rheological parameters. Full article
(This article belongs to the Special Issue Advances in Asphalt Materials (3rd Edition))
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