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Review

2 Citations

2,941 Views

44 Pages

Oncoviruses in the Oral Cavity: Recent Advances in Understanding Viral Infections and Tumorigenesis

Letícia Bomfim Campos,
Ana Carolina Silva Guimarães,
Jéssica Gonçalves Pereira,
Carla Sousa da Silva,
Nathália Alves Araújo de Almeida,
Pedro do Nascimento Marinho,
Rafaela Moraes Pereira de Sousa,
Irena Duś-Ilnicka and
Vanessa Salete de Paula

Int. J. Mol. Sci.2025, 26(14), 6721;https://doi.org/10.3390/ijms26146721

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13 July 2025

Oncoviruses, such as Epstein–Barr virus (EBV), human papillomavirus (HPV), and Kaposi sarcoma-associated herpesvirus (KSHV), have been widely discussed for their oncogenic risk. Initially, the oral cavity was disregarded. In recent years, orien...

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Article

1 Citations

1,425 Views

18 Pages

Applications for Circulating Cell-Free DNA in Oral Squamous Cell Carcinoma: A Non-Invasive Approach for Detecting Structural Variants, Fusions, and Oncoviruses

Mahua Bhattacharya,
Dan Yaniv,
Dylan P. D’Souza,
Eyal Yosefof,
Sharon Tzelnick,
Rajesh Detroja,
Tal Wax,
Adva Levy-Barda,
Gideon Baum and
Milana Frenkel Morgenstern
+ 2 authors

Cancers2025, 17(12), 1901;https://doi.org/10.3390/cancers17121901

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6 June 2025

Background: Circulating cell-free DNA (cfDNA) has been widely used as a prognostic marker for different cancers. Objective: In this study, we used 30 cfDNA samples from oral squamous cell carcinoma (OSCC), 199 public OSCC samples, and 192 normal samp...

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Article

9 Citations

2,584 Views

12 Pages

Epstein-Barr Virus Infection Alone or Jointly with Human Papillomavirus Associates with Down-Regulation of miR-145 in Oral Squamous-Cell Carcinoma

Chukkris Heawchaiyaphum,
Tipaya Ekalaksananan,
Natcha Patarapadungkit,
Suchin Worawichawong and
Chamsai Pientong

Microorganisms2021, 9(12), 2496;https://doi.org/10.3390/microorganisms9122496

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2 December 2021

Down-regulation of tumor-suppressive miR-145 has been reported in various malignancies, including oral squamous-cell carcinoma (OSCC) that is influenced by several factors, including Epstein-Barr virus (EBV) and human papillomavirus (HPV). Oncoviruse...

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