Search Results (83)

Fermented Miang (Camellia sinensis var. assamica) serves as a valuable source of bioactive polyphenols and probiotic-associated components. This study characterized the catechin composition of fermented Miang extracts and evaluated their antioxidant capacity and suitability for cosmetic formulations. High-performance liquid chromatography (HPLC) analysis showed that epigallocatechin gallate (EGCG) was the predominant catechin (7.00 ± 0.93 mg/g dry weight), followed by catechin (C), epicatechin (EC), epicatechin gallate (ECG), and epigallocatechin (EGC). The extracts remained physically and chemically stable for at least three months under various storage conditions, with the dried extract form offering advantages for handling and formulation. Fermentation duration significantly influenced phenolic accumulation and antioxidant activity, with four-month fermentation showing the highest activity. Prototype cleansing formulations, including transparent/opaque soap bars, liquid soap, and shampoo containing fermented Miang extract, exhibited acceptable physicochemical characteristics and retained antioxidant function. These findings highlight fermented Miang as a promising natural ingredient for antioxidant and probiotic-inspired cosmetic applications. Full article

This study investigates how an internal PCM–gypsum plaster lining modifies orientation-dependent heat transfer through lightweight model house envelopes over a full spring season. Two identical container houses (reference and PCM plastered) were monitored for 105 days under free-floating conditions, and surface temperatures of all opaque elements were processed into characteristic temperature differences and corresponding heat flux densities at daily extrema. The analysis showed that wall and roof orientation strongly governed both the magnitude and variability of these characteristic heat fluxes. West-facing façades and the roof exhibited the highest values due to solar gains and radiative exchanges, while the floor and north wall remained comparatively stable. Under conditions of nearly constant mean wall temperature, the characteristic flux framework revealed that the PCM lining systematically reshaped the temporal distribution of heat transfer and reduced the effective net energy exchange between indoor space and outdoor environment, most notably on solar-exposed west and south walls and on the roof. These orientation-resolved heat flux indicators provided a physically transparent basis for deciding on which envelope surfaces PCM integration could be most advantageous and where its application could be omitted without significantly compromising thermal performance under similar climatic conditions. Full article

Convolutional Neural Networks have shown promising effectiveness in identifying different types of cancer from radiographs. However, the opaque nature of CNNs makes it difficult to fully understand the way they operate, limiting their assessment to empirical evaluation. Here we study the soundness of the standard practices by which CNNs are evaluated for the purpose of cancer pathology. Thirteen highly used cancer benchmark datasets were analyzed, using four common CNN architectures and different types of cancer, such as melanoma, carcinoma, colorectal cancer, and lung cancer. We compared the accuracy of each model with that of datasets made of cropped segments from the background of the original images that do not contain clinically relevant content. Because the rendered datasets contain no clinical information, the null hypothesis is that the CNNs should provide mere chance-based accuracy when classifying these datasets. The results show that the CNN models provided high accuracy when using the cropped segments, sometimes as high as 93%, even though they lacked biomedical information. These results show that some CNN architectures are more sensitive to bias than others. The analysis shows that the common practices of machine learning evaluation might lead to unreliable results when applied to cancer pathology. These biases are very difficult to identify, and might mislead researchers as they use available benchmark datasets to test the efficacy of CNN methods. Full article

Cyanate ester resins are widely recognized for their excellent thermal stability, low dielectric loss, and high glass transition temperature, making them attractive for advanced electronic and communication applications. However, their inherent brittleness and limited filler compatibility restricts broader use. In this study, cyanate ester composites were developed by incorporating transparent and opaque borosilicate glass powders modified with silane coupling agents—3-Triethoxysilylpropyl isocyanate (TESPI) and 3-Isocyana-topropyl trimethoxysilane (IPTMS)—to enhance interfacial adhesion and crosslink density. The transparent (CTF) and opaque (COF) composite systems were fabricated with varying filler contents (5–20 wt%), and their structural, mechanical, and dielectric performances were systematically characterized through X-ray Diffraction, Fourier Transform Infrared Spectroscopy, Scanning Electron Microscopy, Energy-Dispersive X-ray Spectroscopy (EDX) and dielectric performance analyses. The results revealed that both filler types enhanced the dielectric and mechanical stability of the cyanate ester matrix; however, the COF-15 composite, containing 15 wt% opaque glass, exhibited the highest tensile strength of approximately 125.70 ± 1.50 MPa, and the dielectric constant increased from 2.86 ± 0.1 (neat matrix) to about 5.0 ± 0.1 while maintaining a low loss tangent (0.007@1 MHz). These improvements were attributed to the zirconium-enriched opaque glass phase, which promoted strong interfacial bonding, compact microstructure, and effective polarization control. Full article

A novel bacterial strain, designated as 4-30^T, was isolated from a soil sample collected from the Kubuqi Desert in Inner Mongolia, northern China. The isolate was a Gram-stain-positive, aerobic, motile, and coccus-shaped bacterium, and its colonies were circular, opaque, convex, smooth, and orange-pigmented on Luria–Bertani agar. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain 4-30^T belonged to the genus Planococcus. Growth occurred at 4–38 °C (optimum, 25–28 °C), pH 6.0–11.0 (optimum, pH 9.0), and in 0–10% (w/v) NaCl (optimum, 1%). Strain 4-30^T contained iso-C_14:0, anteiso-C_15:0, C_16:1 ω7c alcohol, and iso-C_16:0 as major cellular fatty acids (>10%) and MK-7 and MK-8 as predominant menaquinones. Its polar lipid profile consisted of diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, and two unidentified polar lipids. The genomic DNA G+C content was 45.9%. The average nucleotide identity (ANI) values between strain 4-30^T and the closely related species were relatively low (ANIm < 85.6%, ANIb < 82.9% and OrthoANIu < 83.3%), and the digital DNA–DNA hybridization (dDDH) between strain 4-30^T and type strains of the genus Planococcus were 20.0–26.7%. Based on phylogenetic, genotypic, chemotaxonomic, and phenotypic analyses, strain 4-30^T is considered to represent a novel species of the genus Planococcus, for which the name Planococcus circulans sp. nov. is proposed. The type strain is 4-30^T (=CDMCC 1.2409^T = KCTC 43405^T). Full article

Maintaining color constancy in polymer extrusion processes is a key difficulty in manufacturing applications, as fluctuations in processing parameters greatly influence pigment dispersion and the quality of the finished product. Preliminary historical data mining analysis was conducted in 2009. This work concentrates on Opaque PC Grade 5, which constituted 2.43% of the pigment; it contained 10 PPH of resin2 with a Melt Flow Index (MFI) of 6.5 g/10 min and 90 PPH of resin1. It also employs a fixed resin composition with an MFI of 25 g/10 min. This research identified the significant processing parameters (PPs) contributing to the lowest color deviation. Interactions between processing parameters, for the same color formulation, were analyzed using statistical methods under various processing conditions. A principle-driven General Trends (GT) diagnostic procedure was applied, wherein each parameter was individually varied across five levels while holding others constant. Particle size distribution (PSD) and colorimetric data (CIE Lab*) were systematically measured and analyzed. To complete this, correlations for the impact of temperature (Temp) on viscosity, particle characteristics, and color quality were studied by characterizing viscosity, Digital Optical Microscopy (DOM), and particle size distribution at various speeds. The samples were characterized for viscosity at three temperatures (230, 255, 280 °C) and particle size distribution at three speeds: 700, 750, 800 rpm. This study investigates particle processing features, such as screw speed and pigment size distribution. The average pigment diameter and the fraction of small particles were influenced by the speed of 700–775 rpm. At 700 rpm, the mean particle size was 2.4 µm, with 61.3% constituting particle numbers. The mean particle size diminished to 2 µm at 775 rpm; however, the particle count proportion escalated to 66% at 800 rpm. This research ultimately quantifies the relative influence of particle size on the reaction, resulting in a color value of 1.36. The mean particle size and particle counts are positively correlated; thus, reduced pigment size at increased speed influences color response and quality. The weighted contributions of the particles, 51.4% at 700 rpm and 48.6% at 800 rpm, substantiate the hypothesis. Further studies will broaden the GT analysis to encompass multi-parameter interactions through design experiments and will test the diagnostic assessment procedure across various polymer grades and colorants to create robust models of prediction for industrial growth. The global quality of mixing polycarbonate compounding constituents ensured consistent and smooth pigment dispersion, minimizing color streaks and resulting in a significant improvement in color matching for opaque grades. Full article

Mycelium-based composites are self-grown biodegradable materials, made using agricultural residue fibers that are inoculated with fungi mycelium. The mycelium forms an interwoven three-dimensional filamentous network, binding every fiber particle together to create a rigid, lightweight composite material. Although having potential in packaging and in the construction industry, mycelium composites encounter molding limitations due to fiber size and oxygen access which hinder design capabilities and market engagement. To cope with these limitations, this study reports an alternative way to form mycelium composite using cut precultivated mycelium composite panels, laminated to biologically fuse into a unique assembly. By controlling the growth conditions of the mycelium network, it is possible to adjust physical properties such as flexural strength and strain energy density. These mycelium composite panels were fabricated from hemp fibers and Ganoderma lucidum mushroom. Seven different growth conditions were tested to increase layer adhesion and create the strongest assembly. Three-point flexural tests were conducted on ten samples extracted from each assembled panel triplicate set. The data collected in this study suggested that cultivating an opaque layer of mycelium on the surface of the panel before stacking can enhance total strain energy density by approximately 60%, compared to a single-layer mycelium composite of identical size. In addition, this eliminates abrupt material failure by dividing failure behavior into multiple distinct stages. Finally, by layering multiple thinner layers, the resulting mycelium composite could contain even higher mycelium proportions exhibiting augmented mechanical properties and higher design precisions opening market possibilities. Full article

Modern companies often rely on integrating an extensive network of suppliers to organize and produce industrial artifacts. Within this process, it is critical to maintain sustainability and flexibility by analyzing and managing information from the supply chain. In particular, there is a continuous demand to automatically analyze and infer information from extensive datasets structured in various forms, such as natural language and domain-specific models. The advancement of Large Language Models (LLM) presents a promising solution to address this challenge. By leveraging prompts that contain the necessary information provided by humans, LLM can generate insightful responses through analysis and reasoning over the provided content. However, the quality of these responses is still affected by the inherent opaqueness of LLM, stemming from their complex architectures, thus weakening their trustworthiness and limiting their applicability across different fields. To address this issue, this work presents a framework to leverage the graph-based LLM to support the analysis of supply chain information by combining the LLM and domain knowledge. Specifically, this work proposes an integration of LLM and domain knowledge to support an analysis of the supply chain as follows: (1) constructing a graph-based knowledge base to describe and model the domain knowledge; (2) creating prompts to support the retrieval of the graph-based models and guide the generation of LLM; (3) generating responses via LLM to support the analysis and reason about information across the supply chain. We demonstrate the proposed framework in the tasks of entity classification, link prediction, and reasoning across entities. Compared to the average performance of the best methods in the comparative studies, the proposed framework achieves a significant improvement of 59%, increasing the ROUGE-1 F1 score from 0.42 to 0.67. Full article

In the environment, plastic waste degrades into small particles known as microplastics and nanoplastics (MNPLs), depending on their size. Given the potential harmful effects associated with MNPL exposure, it is crucial to develop environmentally representative particles for hazard assessment. These so-called true-to-life MNPLs are generated through in-house degradation of real-world plastic products. In this study, we produced titanium-doped nanoplastics (NPLs) from opaque polyethylene terephthalate (PET) milk bottles, which contain titanium dioxide as a filler. The resulting PET(Ti)-NPLs were thoroughly characterized using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), mass spectrometry (MS), dynamic light scattering (DLS), ζ-potential measurements, transmission electron microscopy (TEM), and Fourier-transform infrared (FTIR) spectroscopy. Human-derived THP-1 monocytes were employed to investigate particle uptake kinetics, dosimetry, and genotoxicity. A combination of flow cytometry and inductively coupled plasma mass spectrometry (ICP-MS) enabled the quantification of internalized particles, while the comet assay assessed DNA damage. The results revealed dose- and time-dependent effects of PET(Ti)-NPLs on THP-1 cells, particularly in terms of internalization. Titanium doping facilitated detection and influenced genotoxic outcomes. This study demonstrates the relevance of using environmentally representative nanoplastic models for evaluating human health risks and underscores the importance of further mechanistic research. Full article

There are discriminatory, structured, opaque human rights violations that keep the socioeconomically vulnerable subservient, a social problem that goes against the core Christian principle: humans are created in the image of God and all share equal dignity. Studies show that sociocultural, political, and economic elements are available in society, which form into clusters, namely social representations, helping people to categorize others and interact with her/him. They carry with them the historical consciousness, providing the people with social-living tools such as social identity and the like. The qualitative empirical research conducted among the Catholic youth of Tamil Nadu, India, showed that the enslaving semantic elements contained in the social knowledge facilitate the youth to affiliate with a group and to disaffiliate from another. Caste-ridden endogamic semantic elements are part of this knowledge. This affects individual as well as social cognition. Therefore, besides conceptual understanding, epistemological approaches are necessary to eliminate the enslaving elements contained in social knowledge. This is possible through the Ego–Alter dialogue. Ego stands for an individual, group, institution, movement, or anything similar. Alter can stand for social knowledge, which is available in society. Full article

The disk of the Milky Way fills the interstellar medium in the form of discrete clouds, many (∼30) light-years across. The average density of this medium is 1 hydrogen atom per cm³ (Oort limit), in the clouds—several dozen atoms, and between the clouds about 0.01 atoms per cm³. It is well documented that physical properties of individual interstellar clouds are evidently different using high-resolution spectroscopic observations of slightly reddened stars. We prove here that the 5780/5797 strength ratio is nearly constant for all slightly reddened targets. The reason for this phenomenon remains unknown. All optically thin clouds are apparently of σ-type. The question of at which value of color excess one may expect a ζ-type cloud remains unanswered. For some (unknown) reason ζ-type clouds are always relatively opaque and contain a lot of molecular species. In all slightly reddened objects we always observe σ-type intervening clouds, almost free of simple molecules. Full article

Antifungal composite beads were prepared using a methylcellulose, alginate, and ethanol solution with the ionic gelation method and ethanol beads (E). A total of 1.0 mL of clove essential oil (CEO) and 1.0 g of vanillin were added to provide an antifungal effect against Aspergillus flavus and Rhizopus stolonifera. Four bead formulations were prepared: ethanol beads (E), ethanol beads containing CEO (EC), ethanol beads containing vanillin (EV), and ethanol beads containing vanillin and CEO (EVC). Ethanol beads were transparent and spherical, whereas those containing CEO or vanillin were spherical and opaque, with diameters ranging from 2.1 to 2.4 mm. The surface and pores in the polymer matrix were investigated in relation to the encapsulation and release of antifungal agents. The bursting release of ethanol and CEO occurred on the first day. Antifungal assays on potato dextrose agar against Aspergillus flavus and Rhizopus stolonifera showed that beads containing CEO (EC and EVC) provided superior inhibition, particularly at a dosage of 1.0 g. In butter cake preservation tests, packaging the butter cake with a sachet containing 1.0 g of EC or EVC beads can extend the shelf life by two days, delaying visible mold growth from day 5 to day 7 compared to the control. Full article

As the severe environmental impacts of plastic pollution demand determined action, the European Union (EU) has included recycling at the core of its policies. Consequently, evolving jurisdiction now aims to achieve a recycling rate of 65% for non-PET plastic bottles by 2040. However, the widespread use of post-consumer high-density polyethylene (rPE-HD) recyclates in household chemical containers is still limited by PP contamination, poor mechanical properties, and low environmental stress cracking resistance (ESCR). Although previous studies have explored the improvement of regranulate properties through additives, few have examined whether reducing the variety of extrusion blow-moulded PE-HD packaging could offer similar benefits. Therefore, two sorted fractions of rPE-HD hollow bodies were processed into regranulates under industrial conditions, including hot washing, extrusion, and deodorisation. Subsequently, both materials underwent comprehensive characterisation regarding their composition and performance. The opaque material, which was sourced from milk bottles in the UK, exhibited greater homogeneity with minor impurities, leading to improved ductility and melt strain hardening at moderate strain rates compared to the mixed material stream, which contained approximately 2.5% PP contamination. However, both rPE-HD recyclates exhibited similar short-term creep behaviour, relatively low strain hardening moduli, and were almost devoid of inorganic particles. Considering the sum of the investigated properties, melt blending with suitable virgin material is likely one of the most effective options to maximise regranulate utilisation in hollow bodies, followed by recycling-oriented packaging design (e.g., for efficient sorting), and the employment of advanced sorting technology. Full article

This contribution provides a petrographic and Raman investigation of fluid inclusions found in chromitites collected in the ophiolites of Santa Elena (Costa Rica), Bracco (Italy), Otrhys and Vourinos (Greece), and Troodos (Cyprus). Most of the analyzed chromites are classified as high-Cr, with the exception of those from Bracco and some of the Othrys complexes that are high-Al. Although the investigation of fluid inclusions in chromitites is very challenging due to the poor transparency of the host chromite, the studied samples contain numerous fluid inclusions. The fluid inclusions look to be more abundant in the high-Cr chromitites, related to a subduction zone environment, compared to the high-Al chromitites generated in a mid-ocean ridge. This is in agreement with the petrogenetic model for the formation of podiform chromitites that implies the presence of a metasomatic event caused by hydrous fluids that reacted pervasively with variable depleted mantle tectonites, especially in the subduction zone setting. The fluid inclusions, between 1 and 15 µm in size, show negative crystal or irregular angular shapes. They occur when enclosed in chromite crystals that have not been affected by low-temperature processes. The fluid inclusions consist of liquid (L), vapour(V~30–50 area%) and L + V (V~40–60 area% rarely 10–80 area%). The fluid inclusions may contain only vapour and a vapour and a solid phase, too. The Raman spectra reveal the presence of CH₄ in certain fluid inclusions. Considering the high number of fluid inclusions that potentially contain CH₄, we suggest that the fluid inclusions in the chromite crystals and their leaching can be a possible source in order to explain the high amount of CH₄ detected in some podiform chromitites, previously attributed to the Sabatier reaction. The mode of the occurrences of the studied CH₄ bearing fluid inclusions, i.e., entrapped in unaltered chromite crystals formed at a magmatic temperature, suggest their abiotic origin from mantle-derived fluids, rather than those related to the low-temperature serpentinization processes. The investigation of fluid inclusions, although it is difficult and challenging or even impossible when the chromite is too opaque, can be applicable to other chromitites worldwide to verify the presence of H₂O, CH₄ or other gases. This information will greatly improve our understanding of the nature of the fluid phases during the formation of podiform chromitites. Full article

Zirconia restorations are widely used in dentistry due to their high esthetic expectations and physical durability. However, zirconia’s opaque white color can compromise esthetics. Therefore, zirconia is often veneered with porcelain, but fractures may occur in the veneer layer. Monolithic zirconia restorations, which do not require porcelain veneering and offer higher translucency, have been developed to address this issue. Zirconia exists in three main crystal phases: monoclinic, tetragonal, and cubic. Metal oxides such as yttrium are added to stabilize the tetragonal phase at room temperature. 3Y-TZP contains 3 mol% yttrium and provides high mechanical strength but has poor optical properties. Recently, 4Y-PSZ and 5Y-PSZ ceramics, which offer better optical properties but lower mechanical strength, have been introduced. This review examines the factors affecting the color change in monolithic zirconia ceramics. These factors are categorized into six main groups: cement type and color, restoration thickness, substrate color, sintering, aging, and zirconia type. Cement type and color are crucial in determining the final shade, especially in thin restorations. Increased restoration thickness reduces the influence of the substrate color while the sintering temperature and process improve optical properties. These findings emphasize the importance of material selection and application processes in ensuring esthetic harmony in zirconia restorations. This review aims to bridge gaps in the literature by providing valuable insights that guide clinicians in selecting and applying zirconia materials to meet both esthetic and functional requirements in restorative dentistry. Full article