Piperidine and pyrrolidine derivatives are important nitrogen heterocyclic structures with a wide range of biological activities. However, reported methods for their construction often face problems of requiring the use of expensive metal catalysts,...
An efficient route to substituted 1-aryl-1H-indazoles has been developed and optimized. The method involved the preparation of arylhydrazones from acetophenone or benzaldehyde substituted by fluorine at C2 and nitro at C5, followed by deprotonation a...
Pure monoclinic vanadium dioxide nanoparticles (VO2 NPs) with a controlled uniform size are considered essential for the preparation of thermochromic smart window coatings on desired substrates. Herein, we report a facile one-step hydrothermal synthe...
Bimetallic copper-tin catalysts are considered cost-effective and suitable for large-scale electrochemical conversion of CO2 to valuable products. In this work, a class of tin (Sn) modified cuprous oxide (Cu2O) is simply synthesized through a one-pot...
A sandwich structured Bi2Te3-nanoplates/graphene-nanosheet (Bi2Te3/G) hybrid has been synthesized by a facile in situ solvothermal route and has been investigated as a potential anode material for Li-ion batteries. Bi2Te3 grows during the solvotherma...
In this study, novel photocatalyst monolith materials were successfully fabricated by a non-solvent induced phase separation (NIPS) technique. By adding a certain amount of ethyl acetate (as non-solvent) into a cellulose/LiCl/N,N-dimethylacetamide (D...
A series of 5%Ni-CexZr1−xO2 (x = 0.3, 0.5, 0.7) catalysts has been prepared via one-pot solvothermal continuous synthesis in supercritical isopropanol and incipient wetness impregnation of CexZr1−xO2 obtained by the same route. The textur...
The framework of 1,3,4-oxadiazine is crucial for numerous bioactive molecules, but only a limited number of synthetic methods have been reported for its production. In 2015, Wang’s group developed a 4-(dimethylamino)pyridine (DMAP)-catalyzed [2...
A copper(I)-mediated one-pot synthesis of 2,3-dihydro-1H-indazole heterocycles has been developed. This synthetic route provides the desired indazoles in moderate to good yields (55%–72%) which are substantially better than those achievable with an a...
In our studies on the catalytic activity of Group IVB transition metal Lewis acids, Hf(OTf)4 was identified as a highly potent catalyst for ”one-pot, three-component” Biginelli reaction. More importantly, it was found that solvent-free co...
The hydroxy-pyrazole and 3-hydroxy-oxindole motifs have been utilised in several pharma and agrochemical leads but are distinctly underrepresented in the scientific literature due to the limited routes of preparation. We have developed a one-pot proc...
This life cycle assessment (LCA) study focused on comparing the environmental performances of two types of synthesis strategies for polyethyleneimine (PEI) coated silica particles (organic/inorganic composites). The classic layer-by-layer and the new...
A one-pot electrochemical synthesis of two medically interesting compounds is presented. 2-Phenylimidazo[1,2-a]pyridine and 2-(4-fluorobenzylidene)malononitrile were prepared using previously used starting materials. The reaction consists of electroc...
Synthetic routes to 5'-azidoribonucleosides are reported for adenosine, cytidine, guanosine, and uridine, resulting in a widely applicable one-pot methodology for the synthesis of these and related compounds. The target compounds are appropriate as p...
The title compound has been synthetized using a one-pot cascade process of ethyl (E)-3-(2-aminophenyl) acrylate and 2-formylbenzonitrile in the presence of Cs2CO3 as the catalyst. The synthetic route has been rationalized as a base-catalyzed tandem a...
In the present paper, we report an expedient total synthesis of triciribine, a tricyclic 7-deazapurine nucleoside and protein kinase B (AKT ) inhibitor, in 35% overall yield. Our synthesis route features a highly regioselective substitution of 1-N-Bo...
Fc-glycosite-specific antibody–drug conjugation represents a promising direction for the preparation of site-specific antibody–drug conjugates (ADCs). In the present research, we conducted a systemic evaluation of two endoglycosidase-cata...
Single-nitrogen containing saturated cyclic amines are an important part of both natural and synthetic bioactive compounds. A number of methodologies have been developed for the synthesis of aziridines, azetidines, pyrrolidines, piperidines, azepanes...
A novel and efficient one-pot three-enzyme cascade method for the synthesis of β-alanine from maleic acid was developed. Two recombinant E. coli strains were constructed. The E. coli (MaiA-AspA) co-expressing maleic cis-trans isomerase (MaiA) an...
Efficient synthesis of phenanthridin-6(5H)-one derivatives 12a–n in a four-component reaction of aldehyde hydrazone, aromatic aldehydes and malononitrile in Q-Tubes is reported. The results showed that the methodology has the advantage of being a one...
Synthesis of janusene (5,5a,6,11,11a,12-hexahydro-5,12:6,11-di-o-benzenonaphthacene) requires several reaction steps, starting from anthracene. In this account, a one-pot, three-step synthesis of janusene N-methyl-5a,11a-dicarboximide employing 2,3-d...
A methodology is reported for the preparation of 2-aryl-benzimidazole-3-oxide derivatives. By means of a one-pot two-step protocol, a library of 42 new compounds has been prepared. Reactions were performed in a total time of 40 min using microwave he...
LaFe0.4Ni0.6O3/CeO2 (1:1) two-phase composite materials were prepared by mechanochemical (MC) and Pechini routes. The catalytic properties of the composites in methane and CO oxidation reactions strongly depend on their preparation conditions. In low...
To explore aggregate-induced emission (AIE) properties, this study adopts a one-pot hydrothermal route for synthesizing polyethylene glycol (PEG)-coated graphene quantum dot (GQD) clusters, enabling the emission of highly intense photoluminescence un...
A series of novel quinoxaline derivatives linked to a pyridine moiety through phenylamino or phenoxy residue was synthesized and evaluated as candidate anticonvulsants. The synthesis was achieved through reaction of 2,3-dichloroquinoxaline (1) with a...
Enzymes are nature’s catalyst of choice for the highly selective and efficient coupling of carbohydrates. Enzymatic sugar coupling is a competitive technology for industrial glycosylation reactions, since chemical synthetic routes require exten...
To improve the practical performance of Na-ion batteries, electrode structure engineering provides a new route to improve the electrochemical efficiency of the cathode active material. In this study, we suggest a new route of one-pot spray engineerin...
A transparent white crystalline product, K[(C2F5)3PF3] (KFAP), has been synthesized via a one-pot route. Difluorotris(pentafluoroethyl)phosphorane was reacted first with aqueous HF then with K2CO3 or KHCO3 in a solution. Isolation of the intermediate...
Sodium hydroxide-modified graphene oxide was used as manganese oxides support for the preparation of nanocomposites via a one-pot preparation route for the degradation of Reactive Black 5. The nanocomposites were characterized for their structure by...
Previously, we demonstrated the synthesis of a well-defined hydroxyalkyl-functionalized N-heterocyclic carbene (NHC)/Ru(II) complex through the transmetalation reaction between [RuCl2(p-cymene)]2 and the corresponding NHC/Ag(I) complex derived from a...
Herein, a one-pot strategy was used to prepare hydrophobic cellulose nanocrystals (CNCs) surface-modified with tannic acid and octadecylamine. By this strategy, CNCs derived from wood (W-CNC) and tunicates (T-CNC) were modified in situ and incorporat...
Chemoenzymatic processes have been gaining interest to implement sustainable reaction steps or even create new synthetic routes. In this study, we combined Grubbs’ second-generation catalyst with pig liver esterase and conducted a chemoenzymati...
Mesoporous carbons (MC) have attracted a tremendous amount of interest due to their efficient molecular transport properties. However, the limited number of active sites and low microporosity generally impede their use for practical applications. Her...
We here described a three-step multi-enzymatic reaction for the one-pot synthesis of vidarabine 5′-monophosphate (araA-MP), an antiviral drug, using arabinosyluracil (araU), adenine (Ade), and adenosine triphosphate (ATP) as precursors. To this...
Lithium-sulfur (Li-S) batteries are postulated as next-generation electrochemical energy storage devices due to their increased storage capabilities. However, challenges persist from the polysulfide-shuttle effect at the cathode. Soluble sulfur-based...
A new one-pot preparative route was developed to synthesize novel organophosphorus-sulfur heterocycles via the reaction of the four-membered ring thionation reagent [2,4-diferrocenyl-1,3,2,4-diathiadiphosphetane 2,4-disulfide (FcLR, a ferrocene analo...
The synthesis of glycosides and modified nucleosides represents a wide research field in organic chemistry. The classical methodology is based on coupling reactions between a glycosyl donor and an acceptor. An alternative strategy for new C-nucleosid...
“One-pot regeneration”, which is simple regneneration method of ammonia borane (AB) using hydrazine and liquid ammonia, enables conversion of AB from hexagonal boron nitride (h-BN) after milling hydrogenation. Solution 11B-NMR revealed th...
Indium tin oxide (ITO) aerogels offer a combination of high surface area, porosity and conductive properties and could therefore be a promising material for electrodes in the fields of batteries, solar cells and fuel cells, as well as for optoelectro...
In search of novel antidiabetic agents, we synthesized a new series of chalcones with benzimidazole scaffolds by an efficient ‘one-pot’ nitro reductive cyclization method and evaluated their α-glucosidase and α-amylase inhibit...
Herein, we present a one-step labeling procedure of N-succinimidyl-4-[18F]-fluorobenzoate ([18F]SFB) starting from spirocyclic iodonium ylide precursors. Precursor syntheses succeeded via a simple one-pot, two-step synthesis sequence, in yields of ap...
Graphene-wrapped ZnO nanocomposites were fabricated by a simple solvothermal technology with a one-pot route. The structure and morphology of these as-fabricated samples were systematically characterized. The adding of graphene enhanced the content o...
A series of novel methyl (R)-N-benzoyl/dichloroacetyl-thiazolidine-4-carboxylates were designed by active substructure combination. The title compounds were synthesized using a one-pot route from l-cysteine methyl ester hydrochloride, acyl chloride,...
A new synthetic pathway to various mono-alkyl-substituted phosphinoboranes HRP–BH2–NMe3 has been developed. The new synthetic route starting from alkyl halides and NaPH2 followed by metalation and salt metathesis is performed in a one-pot...
In this study we demonstrate the synthesis of quaternary semiconductor nanocrystals of stannite Cu2FeSnS4/rhodostannite Cu2FeSn3S8 (CFTS) via mechanochemical route using Cu, Fe, Sn and S elements as precursors in one-pot experiments. Methods of X-ray...
Herein, we present a short and highly modular synthetic route that involves 8-aminoquinoline directed C–H arylation and transamidation chemistry, and which enables access to a wide range of elaborate benzofuran-2-carboxamides. For the directed...
A one-pot route to 2-alkyl and 2-aryl-4H-benzo[d][1,3]oxazin-4-ones (also known as 4H-3,1-benzoxazin-4-ones) has been developed and studied. The method involves the reaction of aryl-substituted anthranilic acids with orthoesters in ethanol catalyzed...
Highly luminescent silicon quantum dots (SiQDs) were prepared via one-pot hydrothermal route. Furthermore, the optimal synthetic conditions, dependence of the emission spectrum on the excitation wavelength and fluorescent stability of SiQDs were inve...
A facile one-pot aqueous solution method has been developed for the fast and straightforward synthesis of SnTe nanoparticles in more than ten gram quantities per batch. The synthesis involves boiling an alkaline Na2SnO2 solution and a NaHTe solution...
Developing a high-activity, robust and economic electrocatalyst for large-scale green hydrogen production is still of great significance. Herein, a novel V6O13 nanosheets self-assembled micro-flower array self-supporting electrode is synthesized usin...
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