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24 pages, 4356 KB  
Article
Design of Recycled Aggregate Fiber-Reinforced Concrete for Road and Airfield Applications Using Polypropylene Fibers and Fly Ash
by Vitalii Kryzhanovskyi, Sergii Kroviakov, Pavlo Shymchenko and Inna Aksyonova
Constr. Mater. 2026, 6(1), 2; https://doi.org/10.3390/constrmater6010002 - 5 Jan 2026
Viewed by 162
Abstract
Driving the circular economy in road construction requires the effective use of secondary materials like recycled concrete aggregate (RCA) and fly ash (FA). A key obstacle is the performance trade-off in concretes incorporating both materials. This research investigates feasible mix designs for road [...] Read more.
Driving the circular economy in road construction requires the effective use of secondary materials like recycled concrete aggregate (RCA) and fly ash (FA). A key obstacle is the performance trade-off in concretes incorporating both materials. This research investigates feasible mix designs for road concrete, using RCA as a full gravel replacement and FA as a cement substitute. Polypropylene fiber (36 mm) and a superplasticizer were utilized to mitigate fresh and hardened state drawbacks. The experimental program included 15 modified mixtures with recycled aggregate and 3 control mixtures with natural aggregate. The workability of all concrete mixtures was kept constant at slump class S1. Road concretes with RCA, containing a 10–12% FA by cement replacement, at least 2 kg/m3 of polypropylene fiber (PF), and 4 kg/m3 of superplasticizer (SP), achieve compressive strength of at least 50 MPa and flexural strength of no less than 5 MPa at the design age. This performance is comparable to that of control mixtures. Furthermore, the abrasion resistance ranges between 0.48–0.50 g/cm2, and the brittleness index falls within 0.095–0.100, significantly enhancing the durability of concrete for rigid pavement applications. The conducted cradle-to-gate life-cycle assessment (stages A1–A3) of the constituent materials for 1 m3 of concrete indicates the following environmental impacts: Global Warming Potential (GWP) of 195 kg CO2 equation, Non-renewable Primary Energy Demand (PENRE) of 1140 MJ, Abiotic Depletion Potential for Fossil resources (ADPF) of 1120 MJ, Acidification Potential (AP) of 0.45 mol H+ equation, and Eutrophication Potential (EP) of 0.07 kg PO43− equation It is established that the modified compositions not only meet the required performance criteria but also contribute to the goals of resource conservation in road construction. Full article
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19 pages, 4383 KB  
Article
Integrating GAN-Generated SAR and Optical Imagery for Building Damage Mapping
by Chia Yee Ho, Bruno Adriano, Gerald Baier, Erick Mas, Sesa Wiguna, Magaly Koch and Shunichi Koshimura
Remote Sens. 2026, 18(1), 134; https://doi.org/10.3390/rs18010134 - 31 Dec 2025
Viewed by 452
Abstract
Reliable assessment of building damage is essential for effective disaster management. Synthetic Aperture Radar (SAR) has become a valuable tool for damage detection, as it operates independently of the daylight and weather conditions. However, the limited availability of high-resolution pre-disaster SAR data remains [...] Read more.
Reliable assessment of building damage is essential for effective disaster management. Synthetic Aperture Radar (SAR) has become a valuable tool for damage detection, as it operates independently of the daylight and weather conditions. However, the limited availability of high-resolution pre-disaster SAR data remains a major obstacle to accurate damage evaluation, constraining the applicability of traditional change-detection approaches. This study proposes a comprehensive framework that leverages generated SAR data alongside optical imagery for building damage detection and further examines the influence of elevation data quality on SAR synthesis and model performance. The method integrates SAR image synthesis from a Digital Surface Model (DSM) and land cover inputs with a multimodal deep learning architecture capable of jointly localizing buildings and classifying damage levels. Two data modality scenarios are evaluated: a change-detection setting using pre-disaster authentic SAR and another using GAN-generated SAR, both combined with post-disaster SAR imagery for building damage assessment. Experimental results demonstrate that GAN-generated SAR can effectively substitute for authentic SAR in multimodal damage mapping. Models using generated pre-disaster SAR achieved comparable or superior performance to those using authentic SAR, with F1 scores of 0.730, 0.442, and 0.790 for the survived, moderate, and destroyed classes, respectively. Ablation studies further reveal that the model relies more heavily on land cover segmentation than on fine elevation details, suggesting that coarse-resolution DSMs (30 m) are sufficient as auxiliary input. Incorporating additional training regions further improved generalization and inter-class balance, confirming that high-quality generated SAR can serve as a viable alternative especially in the absence of authentic SAR, for scalable, post-disaster building damage assessment. Full article
(This article belongs to the Collection Feature Papers for Section Environmental Remote Sensing)
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37 pages, 3612 KB  
Article
Digital Transformation in Design Education: Exploring the Challenges and Opportunities in Jordanian Higher Education
by Islam A. Alshafei, Samah Mohammed AlDweik, Mahmoud ali Hassouneh, Hanan AbuKarki, Abdellatif A. Jarrar and Qusai S. Mansour
Computers 2025, 14(12), 535; https://doi.org/10.3390/computers14120535 - 5 Dec 2025
Viewed by 883
Abstract
In recent years, design education has experienced major changes as the number of digital tools and technologies has rapidly developed. Many design programs encounter difficulties in integrating these innovations, despite their potential benefits. In this research, the adoption of digital tools in the [...] Read more.
In recent years, design education has experienced major changes as the number of digital tools and technologies has rapidly developed. Many design programs encounter difficulties in integrating these innovations, despite their potential benefits. In this research, the adoption of digital tools in the teaching of design in Jordanian universities is explored, focusing on the views of educators in relation to their use, the challenges associated with it, and the resultant effects on the pedagogical process. Faculty members working in various departments of design were surveyed gauging the frequency of usage of tools, their knowledge of new technologies, their perceptions of the potential results of an educational process, and the barriers that were met during the integration process. To guide the analysis, three theoretical frameworks were applied: the SAMR model of technology integration, Bloom’s Digital Taxonomy, and the Technology Acceptance Model (TAM). The findings reveal that while traditional tools like AutoCAD and Revit are predominantly used at the Substitution and Augmentation stages, emerging technologies such as VR/AR and AI show potential for higher-order integration. However, barriers related to ease of use and perceived usefulness limit their broader adoption. The study contributes to the understanding of digital transformation in design education and provides insights into the pedagogical implications for future curriculum development. The research highlights the need to invest more in the professional development of educators and to work more closely with the technological industry. The proposed implications of these insights concern the restructuring of design education to reflect the needs of the digital age and provide approaches to overcoming obstacles to the successful adoption of technology in teaching environments. Full article
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22 pages, 1230 KB  
Review
Extended Reality in Computer Science Education: A Narrative Review of Pedagogical Benefits, Challenges, and Future Directions
by Miguel A. Garcia-Ruiz, Elba A. Morales-Vanegas, Laura S. Gaytán-Lugo, Pablo A. Alcaraz-Valencia and Pedro C. Santana-Mancilla
Virtual Worlds 2025, 4(4), 56; https://doi.org/10.3390/virtualworlds4040056 - 3 Dec 2025
Viewed by 667
Abstract
Technologies such as XR (Extended Reality), in the form of VR (Virtual Reality), AR (Augmented Reality) and MR (Mixed-Reality), are being researched for their potential to support higher education. XR offers novel opportunities for improving understanding and engagement of computer science (CS) courses, [...] Read more.
Technologies such as XR (Extended Reality), in the form of VR (Virtual Reality), AR (Augmented Reality) and MR (Mixed-Reality), are being researched for their potential to support higher education. XR offers novel opportunities for improving understanding and engagement of computer science (CS) courses, abstract and algorithmic thinking and the application of knowledge to solve problems with computers. This narrative literature review aims to report the state of XR adoption in the university CS education context by studying pedagogical benefits, representative cases, challenges, and future research work. Recent case studies have demonstrated that VR innovations are supportive of algorithm and data structure visualization, AR in programming and circuit analysis contextualization, and MR in bridging the experimental practice on virtual with real hardware within computer labs. The potential of XR to enhance engagement, motivation, and complex content understanding has already been researched. However, ongoing obstacles remain such as the high cost of hardware, technical issues in practicing scalable content, restricted access for students with disabilities, and ethical considerations over privacy and data protection. This review also presents XR, not as a substitute for traditional pedagogy, but as an additive tool that, in alignment with well-defined curricular objectives, may enhance CS learning. If it overcomes these deficiencies and progresses appropriate inclusive evidence-based practices, XR has the potential to play a powerful role in the future of computer science education as part of the digital learning ecosystem. Full article
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30 pages, 9989 KB  
Article
Improved A* Algorithm-Based Optimal Path Planning of Rescue Robots Within Multi-Environment Maps
by Jingrui Zhang, Senpeng Wu, Houde Liu, Xiaojun Zhu and Bin Lan
Machines 2025, 13(12), 1099; https://doi.org/10.3390/machines13121099 - 27 Nov 2025
Viewed by 392
Abstract
The traditional A* algorithm performs well in single-map environments, but it is prone to path redundancy and obstacle handling delays in complex multi-map collaborative scenarios, making it unsuitable for the characteristics of multi-environment maps. To address these challenges of traditional A* algorithms, this [...] Read more.
The traditional A* algorithm performs well in single-map environments, but it is prone to path redundancy and obstacle handling delays in complex multi-map collaborative scenarios, making it unsuitable for the characteristics of multi-environment maps. To address these challenges of traditional A* algorithms, this paper proposes a multi-environment map rescue robot path planning method based on an improved A* algorithm. This method introduces an expected cost evaluation function to achieve weighted fusion of path costs and heuristic values from multiple maps, allowing the algorithm to integrate obstacle distributions and weight information across different environments. A random obstacle replacement mechanism is further designed to maintain path feasibility by locally substituting blocked nodes with adjacent accessible nodes, thereby ensuring continuity without global replanning. Through the combination of multi-map information fusion and local obstacle handling, the algorithm generates a globally optimized path that balances planning efficiency, robustness, and adaptability in uncertain rescue scenarios. Experiment results for a 50 × 50 map scenario show that the improved algorithm significantly outperforms single-map planning results in terms of path redundancy, total length, and turning characteristics. The expansion experiments demonstrate that the paths planned by the proposed algorithm are highly consistent with the optimal paths in terms of direction and local deviations, verifying its good feasibility and effectiveness. Full article
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20 pages, 575 KB  
Review
Possible Diagnostic and Therapeutic Applications of Bioprinting for Bone Regeneration in Maxillofacial Surgery
by Lorenzo Marini, Alessandro Tel, Marco Zeppieri, Luca Michelutti, Massimo Robiony, Caterina Gagliano, Fabiana D’Esposito, Matteo Capobianco, Tamara Ius and Marieme Khouyyi
Diagnostics 2025, 15(23), 2978; https://doi.org/10.3390/diagnostics15232978 - 24 Nov 2025
Viewed by 676
Abstract
Background: The integration of 3D bioprinting, biomaterials science, and cellular biology presents a viable strategy for maxillofacial bone regeneration, overcoming the constraints of traditional graft techniques. This review offers a thorough examination of the present condition, obstacles, uses, and future outlook of [...] Read more.
Background: The integration of 3D bioprinting, biomaterials science, and cellular biology presents a viable strategy for maxillofacial bone regeneration, overcoming the constraints of traditional graft techniques. This review offers a thorough examination of the present condition, obstacles, uses, and future outlook of 3D bioprinting technology in maxillofacial bone regeneration. An essential understanding has been attained by analyzing the technological constraints, specifically in vascularization and neuro-integration, and by delineating the vital translational pathway from benchtop models to clinical application. We have examined several bioprinting techniques—namely extrusion, inkjet, and laser-assisted methods—and the requisite bioinks, emphasizing their physicochemical and biological features vital for osteogenesis. Significant clinical applications, including the treatment of trauma-induced abnormalities and the reconstruction of oncology-related resections, have been emphasized. This review highlights the urgent necessity for established regulatory frameworks and refined printing settings to guarantee effective, functional, and durable bone substitutes, providing a distinct pathway for future research and clinical implementation in this specialized surgical domain. Aim: The purpose of this review was to present a general overview of the current clinical and diagnostic applications of bioprinting in bone tissue engineering for the reconstruction of bone defects. Methods: A search of major scientific databases, including PubMed, Science Direct, Embase, and Cochrane, was conducted. Articles published within the last 10 years that analyze the possible applications of bioprinting in bone tissue fabrication were included. Results: Several bioinks, based on hydrogels and stem cells, can enable the fabrication of such tissues using this technology. This review reports on the processes adopted for the bioprinting of bone tissue, the bioinks used, and cell cultivation methods. Conclusions: Bioprinting represents a promising solution for bone regeneration with potential applications that could revolutionize current surgical practices, despite the many challenges that future research will face. Full article
(This article belongs to the Section Clinical Diagnosis and Prognosis)
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22 pages, 5926 KB  
Article
Evaluation and Enhancement of Landscape Resilience in Mountain–Water Towns from the Perspective of Cultural and Tourism Integration: Case Study of Yinji Town, Wugang City
by Huaijing Wu, Shuo Liu, Hu Li, Wenqi Wang, Lijuan Niu and Hong Zhang
Sustainability 2025, 17(21), 9806; https://doi.org/10.3390/su17219806 - 3 Nov 2025
Cited by 1 | Viewed by 826
Abstract
Rural tourism in China is advancing rapidly, with cultural and tourism integration (CTI) becoming a vital pathway for sustainability. Mountain–water towns, given their special geographical conditions, face numerous challenges in CTI development, which need to enhance landscape resilience. This study proposes the theoretical [...] Read more.
Rural tourism in China is advancing rapidly, with cultural and tourism integration (CTI) becoming a vital pathway for sustainability. Mountain–water towns, given their special geographical conditions, face numerous challenges in CTI development, which need to enhance landscape resilience. This study proposes the theoretical framework of landscape resilience in mountain–water towns from the perspective of CTI. Taking Yinji Town of Wugang City as an example, it constructs a resilience evaluation system including three dimensions: cultural landscape, natural landscape, and social systems. The study uses the AHP–Entropy Weight combined method to determine indicator weights. Indicator scores are obtained through field research and GIS analysis, which are substituted into the preparedness–vulnerability resilience model to calculate resilience level, and the Jenks Natural Breaks method is used for level classification. Finally, the Obstacle Degree Model is applied to identify the primary obstacle factors affecting landscape resilience. The results indicate the following: (1) The average landscape resilience (RI) score of the 19 villages in Yinji Town is 0.84 (RI < 1), indicating a generally low level. Two villages are in the high-level range, while four villages are in the low-level range. (2) Cultural landscape resilience is the primary weakness, with the lowest average score (0.70), while natural landscape resilience is the highest (1.03). (3) Major obstacles include such as the number of cultural inheritors, the degree of susceptibility to natural disasters, and the distance to core mountain–water resources. The study contributes a CTI-based evaluation framework and methodology for assessing landscape resilience, offering enhancement strategies through increased preparedness and reduced vulnerability. Full article
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21 pages, 963 KB  
Article
Expert Perspectives on Enhancing Analytical Methods for Multi-Ingredient Dietary Supplements (MIDS): A Qualitative Study
by Ingyeong Ko, Hae Jin Park, Kwang Suk Ko, Hyunsoo Kim and Jieun Oh
Foods 2025, 14(21), 3598; https://doi.org/10.3390/foods14213598 - 22 Oct 2025
Viewed by 1006
Abstract
The increasing demand for multi-ingredient dietary supplements (MIDS), driven by diverse consumer health needs, has introduced analytical challenges in product testing and quality control. These challenges stem from complex ingredient interactions, formulation variability, and the diverse physicochemical properties of the individual components. To [...] Read more.
The increasing demand for multi-ingredient dietary supplements (MIDS), driven by diverse consumer health needs, has introduced analytical challenges in product testing and quality control. These challenges stem from complex ingredient interactions, formulation variability, and the diverse physicochemical properties of the individual components. To examine these issues and explore practical solutions, this study employed semi-structured focus group interviews with 33 industry professionals and 10 analytical experts from academic and industry. Professionals reported major obstacles including the degradation or loss of trace components, interferences among ingredients, analytical difficulties with specific dosage forms, and the lack of standardized testing protocols. To mitigate these challenges, professionals reported implementing various combination strategies including substituting problematic raw materials and modifying analytical instruments and pretreatment procedures, in order to improve test reproducibility. These measures were developed internally and varied significantly across companies, reflecting the absence of a unified analytical framework for MIDS testing. Building on these insights, the analytical experts proposed systematic improvements including developing matrix-specific pretreatment protocols and optimized extraction strategies as well as regulatory harmonization to enhance analytical reliability and reproducibility. These findings provide critical insights into current field practices and inform the development of standardized methodologies for the analysis and quality assurance of MIDS. Full article
(This article belongs to the Section Nutraceuticals, Functional Foods, and Novel Foods)
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24 pages, 2067 KB  
Review
Coconut Coir Fiber Composites for Sustainable Architecture: A Comprehensive Review of Properties, Processing, and Applications
by Mohammed Nissar, Chethan K. N., Yashaswini Anantsagar Birjerane, Shantharam Patil, Sawan Shetty and Animita Das
J. Compos. Sci. 2025, 9(10), 516; https://doi.org/10.3390/jcs9100516 - 26 Sep 2025
Cited by 3 | Viewed by 10038
Abstract
The growing need for sustainable materials in architecture has sparked significant interest in natural-fiber-based composites. Among these, coconut coir, a by-product of the coconut industry, has emerged as a promising raw material owing to its abundance, renewability, and excellent mechanical properties. The promise [...] Read more.
The growing need for sustainable materials in architecture has sparked significant interest in natural-fiber-based composites. Among these, coconut coir, a by-product of the coconut industry, has emerged as a promising raw material owing to its abundance, renewability, and excellent mechanical properties. The promise of coir-based composites in architecture is highlighted in this review, which also looks at their problems, advantages for the environment, manufacturing processes, and mechanical, thermal, and acoustic performances. The fibrous shape of the coir provides efficient thermal and acoustic insulation, while its high lignin concentration guarantees stiffness, biological resistance, and dimensional stability. Fiber-matrix adhesion and durability have improved owing to advancements in treatment and environmentally friendly binders, opening up the use of cement, polymers, and hybrid composites. In terms of the environment, coir composites promote a biophilic design, reduce embodied carbon, and decrease landfill waste. Moisture sensitivity, inconsistent fiber quality, and production scaling are obstacles; however, advancements in hybridization, grading, and nanotechnology hold promise. This review provides comprehensive, architecture-focused review that integrates material science, fabrication techniques, and real-world architectural applications of coir-based composites. Coir-based composites have the potential to be long-lasting, sustainable substitutes for conventional materials in climate-resilient architectural design if they are further investigated and included in green certification programs and the circular economy. Full article
(This article belongs to the Special Issue Composites: A Sustainable Material Solution, 2nd Edition)
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27 pages, 2622 KB  
Article
The Role and Potential of Timber in Construction for Achieving Climate Neutrality Objectives in Latvia
by Edgars Pudzis, Antra Kundziņa and Pēteris Druķis
Sustainability 2025, 17(18), 8247; https://doi.org/10.3390/su17188247 - 13 Sep 2025
Viewed by 1479
Abstract
Low-carbon development is closely linked to the concept of sustainability, which focuses on both economic growth and the targeted reduction of greenhouse gas (GHG) emissions, facilitating the transition to climate neutrality. This process involves the efficient use of resources and necessitates systemic transformations [...] Read more.
Low-carbon development is closely linked to the concept of sustainability, which focuses on both economic growth and the targeted reduction of greenhouse gas (GHG) emissions, facilitating the transition to climate neutrality. This process involves the efficient use of resources and necessitates systemic transformations across various sectors of the economy. For Latvia to achieve its climate neutrality objectives, it is essential to adhere to the principles of the bioeconomy, with a particular emphasis on the use of timber in construction. This approach combines opportunities for economic development with environmental protection, as timber is a renewable resource that contributes to carbon sequestration. The utilisation of timber in construction enables carbon storage within buildings and substitutes traditional materials such as concrete and steel, the production of which is highly energy-intensive and generates substantial CO2 emissions. Consequently, timber use also reduces indirect emissions associated with the construction sector. The objective of this study is to identify the main barriers hindering the broader application of timber construction materials in Latvia’s building sector and to propose solutions to overcome these obstacles. The research tasks include an analysis of climate neutrality and construction targets within the EU and Latvia; an examination of the current situation and influencing factors regarding Latvia’s forest resources, their harvesting, processing, use in construction, and trade balance; and the identification of critical problem areas and the delineation of possible solutions. For theoretical and situational analyses, the authors employ methods such as scientific literature review, policy content analysis, descriptive methodology, statistical data analysis, and interpretation of quantitative and qualitative data. The results are synthesised using PESTEL analysis, which serves as a continuation and elaboration of the initial SWOT analysis assessment and is visualised through graphical representation. The authors of this study participated in a national-level expert group whose members represented the Parliament of the Republic of Latvia, responsible ministries, forest managers, construction companies, wood product manufacturers, and representatives from higher education and research institutions. The following hypotheses are proposed and substantiated in this article: (1) Latvia possesses sufficient forest resources to increase the share of timber used in construction, (2) increasing the use of timber in construction would significantly contribute to both Latvia’s economic development and the achievement of climate neutrality targets, and (3) the expansion of timber use in the construction sector depends on a restructuring of national policy across multiple sectors. Suggested solutions include the improvement of regulatory frameworks for timber harvesting, processing, and utilisation in related sectors—agriculture and forestry, wood processing, and construction. The key challenges for policymakers include addressing the identified deficiencies in Latvia’s progress toward achieving its CO2 targets, introducing qualitative changes in timber harvesting conditions, and amending regulations governing the forest management cycle accordingly. For timber processing companies, it is crucial to ensure stable conditions for their commercial activity. Promoting the use of timber in construction requires a broad set of changes in safety and financial regulations and procurement requirements. Timber construction is relevant not only in the building sector but also in civil engineering, and modifications and additions to educational programmes are necessary. The promotion of timber use among the wider public is of great importance. At all stages of timber processing—from harvesting to integration in buildings—access to financial resources should be facilitated. As numerous sectors of the national economy (agriculture, forestry, wood processing, construction, logistics, etc.) are involved in timber processing, interdisciplinary research is required to address complex challenges that demand expertise from multiple fields. Full article
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18 pages, 330 KB  
Review
Current Processing Technologies and Challenges in Hybrid Meat Production
by Nikola Stanišić, Nikola Delić, Bogdan Cekić, Nenad Stojiljković, Marija Gogić, Ljiljana Samolovac and Slaviša Stajić
Processes 2025, 13(9), 2853; https://doi.org/10.3390/pr13092853 - 5 Sep 2025
Viewed by 1764
Abstract
Hybrid meat products, i.e., the combination of animal proteins with plant, microbial, algal or cultured ingredients, are becoming increasingly important as a pragmatic approach to reducing the environmental and health impact of conventional meat while retaining familiar sensory properties. This review highlights that [...] Read more.
Hybrid meat products, i.e., the combination of animal proteins with plant, microbial, algal or cultured ingredients, are becoming increasingly important as a pragmatic approach to reducing the environmental and health impact of conventional meat while retaining familiar sensory properties. This review highlights that moderate substitution rates (20–50%) can maintain or improve texture, juiciness and nutritional balance, whereas higher incorporation rates often lead to off-flavours, colour changes and texture issues. Advances in extrusion, co-processing and protein structuring have enabled increasingly sophisticated formulations. Studies show that the choice of ingredients has a strong influence on the sensory results. For example, faba beans, rice by-products or insect proteins are more acceptable at low to moderate levels, while excessive use of pulses or texturised proteins can produce beany or earthy notes. Nutritional improvements, such as more fibre and healthier fatty acid profiles, are possible but require careful optimisation. Consumer acceptance is increasing, particularly among flexitarians, but remains dependent on sensory performance, familiarity, and perceived health benefits. Ongoing obstacles include unclear regulatory requirements, high production costs and scalability issues. Future progress will require optimisation of ingredient blends, robust life cycle assessments to verify sustainability claims and transparent communication to increase consumer confidence. Full article
31 pages, 2695 KB  
Article
Multidimensional Risk Assessment in Sustainable Coal Supply Chains for China’s Low-Carbon Transition: An AHP-FCE Framework
by Yang Zhou, Ming Guo, Junfang Hao, Wanqiang Xu and Yuping Wu
Sustainability 2025, 17(13), 5689; https://doi.org/10.3390/su17135689 - 20 Jun 2025
Cited by 1 | Viewed by 1489
Abstract
Driven by the global energy transition and the pursuit of “dual carbon” goals, sustainability risks within the coal supply chain have emerged as a central obstacle impeding the low-carbon transformation of high-carbon industries. To address the critical gap in systematic and multidimensional risk [...] Read more.
Driven by the global energy transition and the pursuit of “dual carbon” goals, sustainability risks within the coal supply chain have emerged as a central obstacle impeding the low-carbon transformation of high-carbon industries. To address the critical gap in systematic and multidimensional risk assessments for coal supply chains, this study proposes a hybrid framework that integrates the analytic hierarchy process (AHP) with the fuzzy comprehensive evaluation (FCE) method. Utilizing the Delphi method and the coefficient of variation technique, this study develops a risk assessment system encompassing eight primary criteria and forty sub-criteria. These indicators cover economic, operational safety, ecological and environmental, management policy, demand, sustainable supply, information technology, and social risks. An empirical analysis is conducted, using a prominent Chinese coal enterprise as a case study. The findings demonstrate that the overall risk level of the enterprise is “moderate”, with demand risk, information technology risk, and social risk ranking as the top three concerns. This underscores the substantial impact of accelerated energy substitution, digital system vulnerabilities, and stakeholder conflicts on supply chain resilience. Further analysis elucidates the transmission mechanisms of critical risk nodes, including financing constraints, equipment modernization delays, and deficiencies in end-of-pipe governance. Targeted strategies are proposed, such as constructing a diversified financing matrix, developing a blockchain-based data-sharing platform, and establishing a community co-governance mechanism. These measures offer scientific decision-making support for the coal industry’s efforts to balance “ensuring supply” with “reducing carbon emissions”, and provide a replicable risk assessment paradigm for the sustainable transformation of global high-carbon supply chains. Full article
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24 pages, 2668 KB  
Review
Biosimilars Targeting Pathogens: A Comprehensive Review of Their Role in Bacterial, Fungal, Parasitic, and Viral Infections
by Mohamed Halawa, Ramez M. Rashad ElSayed, Tope Aderibigbe, Precious M. Newman, Briana E. Reid and Valerie J. Carabetta
Pharmaceutics 2025, 17(5), 581; https://doi.org/10.3390/pharmaceutics17050581 - 28 Apr 2025
Cited by 5 | Viewed by 1928
Abstract
Biosimilars represent medicinal products that exhibit a high degree of similarity to an already sanctioned reference biologic agent, with negligible clinically significant disparities concerning safety, purity, or potency. These therapeutic modalities are formulated as economically viable substitutes for established biologics, thereby facilitating increased [...] Read more.
Biosimilars represent medicinal products that exhibit a high degree of similarity to an already sanctioned reference biologic agent, with negligible clinically significant disparities concerning safety, purity, or potency. These therapeutic modalities are formulated as economically viable substitutes for established biologics, thereby facilitating increased accessibility to sophisticated treatments for a range of medical conditions, including infectious diseases caused by bacterial, fungal, and viral pathogens. The current landscape of biosimilars includes therapeutic proteins, such as monoclonal antibodies, antimicrobial peptides, antiviral peptides, and antifungal peptides. Here, we discuss the obstacles inherent in the development of biosimilars, including the rapid mutation rates of pathogens. Furthermore, we discuss innovative technologies within the domain, including antibody engineering, synthetic biology, and cell-free protein synthesis, which exhibit potential for improving the potency and production efficiency of biosimilars. We end with a prospective outlook to highlight the importance and capacity of biosimilars to tackle emerging infectious diseases, highlighting the imperative need for ongoing research and financial commitment. Full article
(This article belongs to the Special Issue State of the Art of Membrane Active Peptides, 2nd Edition)
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37 pages, 4763 KB  
Review
Bio-Based Stabilization of Natural Soil for Rammed Earth Construction: A Review on Mechanical and Water Durability Performance
by Taiwo Sesay, Yuekai Xie, Yue Chen and Jianfeng Xue
Polymers 2025, 17(9), 1170; https://doi.org/10.3390/polym17091170 - 25 Apr 2025
Cited by 5 | Viewed by 4424
Abstract
Rammed earth (RE), despite being an ancient method of construction, has smoothly integrated into contemporary civil engineering due to its compatibility with current sustainability requirements for housing structures. However, typical RE needs some improvements to fully realize its potential as both a structurally [...] Read more.
Rammed earth (RE), despite being an ancient method of construction, has smoothly integrated into contemporary civil engineering due to its compatibility with current sustainability requirements for housing structures. However, typical RE needs some improvements to fully realize its potential as both a structurally effective and environmentally friendly building technique. As a result, multiple bio-inspired enhancement methods have been suggested to substitute traditional cement or lime stabilizers. This review examines the various efforts made in the past decade to biologically stabilize natural soil for the construction of RE. It provides a brief overview of the different bio-based materials utilized in this area but primarily concentrates on their effects on the mechanical strength and water durability of RE structures. The review also addresses current obstacles that prevent the widespread industrial adoption of this valuable earth-building method and identifies potential directions for future research. Overall, the available literature on the mechanical performance and durability of bio-based rammed earth (BRE) shows encouraging outcomes. Nonetheless, various issues, such as the absence of thorough data on the discussed topics, issues related to the inherent properties of soil and biomaterials, and doubts regarding the reliability of durability evaluation methods, have been identified as factors that could lead to a lack of confidence among RE practitioners in adopting bio-based treatments. This study will provide a solid foundation for future researchers aiming to advance BRE technology, thus enhancing sustainability within the construction sector. Full article
(This article belongs to the Section Polymer Applications)
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25 pages, 2077 KB  
Review
Sustainable Transition of the Global Semiconductor Industry: Challenges, Strategies, and Future Directions
by Yilong Yin and Yi Yang
Sustainability 2025, 17(7), 3160; https://doi.org/10.3390/su17073160 - 2 Apr 2025
Cited by 18 | Viewed by 19261
Abstract
The semiconductor industry is essential to information technology and the ongoing artificial intelligence transformation but also poses significant environmental challenges, including greenhouse gas emissions, air pollution, solid waste, and high water and energy consumption. This review identifies key emission sources in semiconductor manufacturing, [...] Read more.
The semiconductor industry is essential to information technology and the ongoing artificial intelligence transformation but also poses significant environmental challenges, including greenhouse gas emissions, air pollution, solid waste, and high water and energy consumption. This review identifies key emission sources in semiconductor manufacturing, focusing on the release of fluorinated gases from chemical-intensive processes and the sector’s substantial energy demands. We evaluate the effectiveness and limitations of current mitigation strategies, such as process optimization, clean energy adoption, and material substitution. We also examine supply chain interventions, including green procurement, logistics optimization, and intelligent management systems. While technological innovation is crucial for the sustainable transition of the global semiconductor industry, the high cost of upgrading to greener production processes remains a major obstacle. Despite progress in clean energy integration and material alternatives, significant challenges persist in reducing emissions across the entire value chain. This review underscores an urgent need for collaborative, integrated approaches to drive the sustainable transition of the semiconductor sector and its upstream supply chain. Full article
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